Personally I'd never run tne that often. It aromatizes like a mother fucker. When I first started using it I ran it 4-5 times a week but not on a schedule. Some times the days were back to back and some times it was eod. I used it for a pre w/o. I had issues keeping control of my e2. I got bloods done at one point with .25mg adex eod and my e2 was pretty fucking high. I didn't have any noticeable sides but bloods showed I was having issues. I tried playing with the dose of adex, .5mg eod, .25mg ed .5mg ed but I was either too high or too low. Tne is very hard to keep stable bloods with because of the lack of ester. I don't recommend it.