Thread: Nandrolone question...

Originally Posted by Del1964

Nandrolone: "It also appears less effective in activity on nerve cells, specifically on the nerve cells responsible for erectile function. Use of Deca as the sole AAS often results in complete inability to perform sexually"
Question is ...Does Nandrolone affect the libido/desire? Or does it actually only affect the dickeroo and it's ability to fill with blood? Or are the limp situation only at high levels. 250mg safe level as far as this goes per week?

Yes. 250mg will shut you down and you most likely will have libido issues. That's why test is ALWAYS recommended to be used at twice the amount of nandrolone in most cases.

Originally Posted by CT

Yes. 250mg will shut you down and you most likely will have libido issues. That's why test is ALWAYS recommended to be used at twice the amount of nandrolone in most cases.

Thanks CT...just wanted to be clear that I was wondering if Libido which is "desire" obviously ....is different than not being able to "get it up." In other words is it possible to really really want some of that hot babe......butttttt not be able to "get it up" (because of Deca) because of some enzyme issue associated with the male "equipment"? But yes, from what I've read, Testosterone is very necessary while running Deca.

Originally Posted by CT

Yes. 250mg will shut you down and you most likely will have libido issues. That's why test is ALWAYS recommended to be used at twice the amount of nandrolone in most cases.

This is 100%!

-TG

Originally Posted by Del1964

Thanks CT...just wanted to be clear that I was wondering if Libido which is "desire" obviously ....is different than not being able to "get it up." In other words is it possible to really really want some of that hot babe......butttttt not be able to "get it up" (because of Deca) because of some enzyme issue associated with the male "equipment"? But yes, from what I've read, Testosterone is very necessary while running Deca.

Soft erections and trouble finishing are common reports of Nandrolone users. Keep you Deca dose reasonable and T dose high. Also very high E2 can cause libido issues so an AI would be wise to use with the test.

I use a good stiff dose of test with it and hCG. hCG seems to help a lot.

long ago hcg was the dick drug because, there was no viagara or shit like that. proviron was used at times but took longer to work as hcg is im at least by the guys i know, knew.

Originally Posted by heavyiron

Soft erections and trouble finishing are common reports of Nandrolone users. Keep you Deca dose reasonable and T dose high. Also very high E2 can cause libido issues so an AI would be wise to use with the test.

Heavy, I have had this issue since a cycle of Mdrol/P-Plex that I took last winter. Now I spend almost the entire time during sex TRYING to finish. I am on cycle now, and it seems to have helped, but I still have trouble finishing, and very occasionally the erection will go away.

Any ideas what the hell could be behind this? The erectile part isnt such a big deal, because it is rare, but the trouble finishing is every single time, regardless of partner or activity (including masturbation).

Originally Posted by heavyiron

Soft erections and trouble finishing are common reports of Nandrolone users. Keep you Deca dose reasonable and T dose high. Also very high E2 can cause libido issues so an AI would be wise to use with the test.

Sorry...lost me on "high E2"... Estrogen levels? Been out of the game for a while so had to look up "AI": Aromatase Inhibitor= Arimidex. Otherwise, thanks for the expertise advice! Higher Test and Arimidex with Deca should do the trick and also Cialis on hand!

I might get heat for this but here goes. The arcuate nucleus joining the hypothalamus and pituitary is lined with a series of neurons that are dopaminergic. They secrete dopamine. Dopamine is required in this region to suppress prolactin among other protein hormones. Prolactin at a break through level leads to a feeling of satis that is experienced after orgasm and it's dissipation is correlated with the refractory period seen between successful coital activity. These neurons have progesterone receptors. Nandrolones, trenbolones and their metabolites bind these progesterone receptors leading to decreased dopamine secretion. This is localized to the hypothalamus/pituitary region and does not significantly affect overall blood levels of prolactin. This is why prolactin levels are not always seen to rise in 19 nor andros sexual dysfunction. The way to resolve the problem is to wait until the nandrolone/trenbolone and metabolites dissipate and or use a D2 agonist temporarily until those nandrolone/metabolite levels resolve.

Originally Posted by jmorrison

Heavy, I have had this issue since a cycle of Mdrol/P-Plex that I took last winter. Now I spend almost the entire time during sex TRYING to finish. I am on cycle now, and it seems to have helped, but I still have trouble finishing, and very occasionally the erection will go away.

Any ideas what the hell could be behind this? The erectile part isnt such a big deal, because it is rare, but the trouble finishing is every single time, regardless of partner or activity (including masturbation).

I would get full hormonal labs including prolactin.

Originally Posted by Glycomann

I might get heat for this but here goes. The arcuate nucleus joining the hypothalamus and pituitary is lined with a series of neurons that are dopaminergic. They secrete dopamine. Dopamine is required in this region to suppress prolactin among other protein hormones. Prolactin at a break through level leads to a feeling of satis that is experienced after orgasm and it's dissipation is correlated with the refractory period seen between successful coital activity. These neurons have progesterone receptors. Nandrolones, trenbolones and their metabolites bind these progesterone receptors leading to decreased dopamine secretion. This is localized to the hypothalamus/pituitary region and does not significantly affect overall blood levels of prolactin. This is why prolactin levels are not always seen to rise in 19 nor andros sexual dysfunction. The way to resolve the problem is to wait until the nandrolone/trenbolone and metabolites dissipate and or use a D2 agonist temporarily until those nandrolone/metabolite levels resolve.

Sounds reasonable. Please provide your source.

Originally Posted by heavyiron

Sounds reasonable. Please provide your source.

I'll have to dig them up tonight. It is not a single source. Rather it comes from multiple sources and some thinking. I'll dig up some stuff on the dopaminanergic neurons of the arcuate nucleus since that is at the heart of it. Now that I've brought it up Heavy you've probably already found the articles.

edit: here is one but there are a number out there.

Neuroendocrinology. 2005;82(1):21-31. Epub 2005 Dec 5.
Progesterone-receptive dopaminergic and neuropeptide Y neurons project from the arcuate nucleus to gonadotropin-releasing hormone-rich regions of the ovine preoptic area.

Dufourny L, Caraty A, Clarke IJ, Robinson JE, Skinner DC.

Department of Zoology & Physiology, University of Wyoming, Laramie, WY 82071, USA.
Abstract

Progesterone inhibits gonadotropin-releasing hormone (GnRH) secretion in sheep through an interneuronal system located in the mediobasal hypothalamus. This study focused on known inhibitors of GnRH secretion in sheep, dopamine and neuropeptide Y (NPY). As the distributions of tyrosine hydroxylase (TH)- and NPY-immunoreactive neurons overlap with progesterone receptors (PR) in the arcuate nucleus, we hypothesized that, if these neurons mediate, at least partially, the inhibitory feedback signal of progesterone, then they should co-express PRs. Fluorogold (FG), a retrograde tracer, was injected into the preoptic area of ovariectomized ewes pretreated with estrogen and progesterone. When the FG injection site encompassed at least 80 GnRH neurons, sections from the arcuate nucleus were processed using dual immunocytochemistry for PR and either TH or NPY. We found that 30% of PR-immunoreactive, 12% of TH-containing and 21% of NPY-synthesizing neurons project toward this GnRH-rich region. Of the PR/TH dual-labeled cells, which represent 21% of PR and 31% of TH cells, respectively, 22% displayed FG labeling. Of the PR/NPY neurons, which account for 19% of PR and 67% of NPY neurons, respectively, 26% were FG fluorescent. This study suggests that subsets of arcuate nucleus dopaminergic and NPY neurons may transduce, at least in part, the progesterone-mediated inhibition of GnRH secretion.

PMID: 16330883 [PubMed - indexed for MEDLINE]

Originally Posted by Glycomann

I might get heat for this but here goes. The arcuate nucleus joining the hypothalamus and pituitary is lined with a series of neurons that are dopaminergic. They secrete dopamine. Dopamine is required in this region to suppress prolactin among other protein hormones. Prolactin at a break through level leads to a feeling of satis that is experienced after orgasm and it's dissipation is correlated with the refractory period seen between successful coital activity. These neurons have progesterone receptors.

That's what I'm talking about. Real studies with real science. The human body is just an incredible machine. And you have to wonder if science will ever really know how everything interacts.

I can only tell from personal experience, using 400mg e/w...

During cycle:
First 10 weeks: Horny as hell
Week 10-14: Not so horny.. but no problems getting it up.

After cycle:
"One day": NOT BEING ABLE TO GET IT UP" (Could be mental issues also )
Then for 1-2 months my sex drive was LOW (but still no problems getting it up).

Even though I always got it up, I wasn't really horny if you know what I mean. It wasn't "in me".. I just fucked by will. Hehehe...


Like everybody says; Throw some test in!

Originally Posted by Del1964

Nandrolone: "It also appears less effective in activity on nerve cells, specifically on the nerve cells responsible for erectile function. Use of Deca as the sole AAS often results in complete inability to perform sexually"
Question is ...Does Nandrolone affect the libido/desire? Or does it actually only affect the dickeroo and it's ability to fill with blood? Or are the limp situation only at high levels. 250mg safe level as far as this goes per week?

hey man deca uses your owen test to work thats what they call deca dick so get some test and you wont have that problem .

Good Morning / Evening guys !
I am in the understanding of running test with deca, no problem right? Well here is where my litte brain becomes over analytical. I am about to run a deca/test blend which i think the blend is proper, but what should one do after a cycle? I just have read so much about persons pct product choices. I just need a straight product answer, and any help would be most appreciated !
Thanks !

Medications are used to treat

Originally Posted by systemseo122

Medications are used to treat

Indian spammers are used to spam.

Originally Posted by Soldier-4-Hire

Good Morning / Evening guys !
I am in the understanding of running test with deca, no problem right? Well here is where my litte brain becomes over analytical. I am about to run a deca/test blend which i think the blend is proper, but what should one do after a cycle? I just have read so much about persons pct product choices. I just need a straight product answer, and any help would be most appreciated !
Thanks !

i dont know how old most of u guys are around here, but u can run 200-250 a week of test damn near the rest of ur life and not have any adverse side effects, then u dont have to worry about a pct, just have some AI on hand when u run ur stuff real high. my dad is 64 yrs old and has been on prescription t for oh about 5 years now at 250 a week, never had a problem. Just a thought