Thread: Proper pct

No, adex cannot and should not..
Aromasin yes, but only after a aromatizing compound or in conjunction with SERM...
Osta SARM would be a great add to every PCT as well because you will not lose any lean mass.. It is a non suppressive anabolic.

Clomid and Aromasin is the way to go. Some just use Clomid with no A/I, but I think the A/I is a good idea.

Originally Posted by MDR

Clomid and Aromasin is the way to go. Some just use Clomid with no A/I, but I think the A/I is a good idea.

So I should take clomid with an AI. Do u mean aromasin or arimedix?

Originally Posted by alan84

So I should take clomid with an AI. Do u mean aromasin or arimedix?

Aromasin is better for PCT.

Adex tends to cause a estrogen rebound which is not good for PCT.

Originally Posted by chronicelite

Aromasin is better for PCT.

Adex tends to cause a estrogen rebound which is not good for PCT.

Exactly

i do not think any ai should be taken in pct....clomid and nolva acts as a ai, so there is no need for it. Clomid and Nolvadex are both anti-estrogens belonging to the same group of triphenylethylene compounds. They are structurally related and specifically classified as selective estrogen receptor modulators (SERMs) with mixed agonistic and antagonistic properties. This means that in certain tissues they can block the effects of estrogen, by altering the binding capacity of the receptor, while in others they can act as actual estrogens, activating the receptor. In men, both of these drugs act as anti-estrogens in their capacity to oppose the negative feedback of estrogens on the hypothalamus and stimulate the heightened release of GnRH (Gonadotropin Releasing Hormone). LH output by the pituitary will be increased as a result, which in turn can increase the level of testosterone by the testes.

I cant argue with Pyes perfect text book answer or MDR/Chronic/Gamer's suggestions. Both are valid. Aromasin is better for PCT than Adex. I personally choose to not use either during PCT as for me I feel Clomid is sufficient.

Thanks to all of you guys for the responses. I will get some clomid for my pct.

Originally Posted by MDR

Clomid and Aromasin is the way to go. Some just use Clomid with no A/I, but I think the A/I is a good idea.

Originally Posted by chronicelite

Aromasin is better for PCT.

Adex tends to cause a estrogen rebound which is not good for PCT.

^^This^^


/V

Originally Posted by pyes

i do not think any ai should be taken in pct....clomid and nolva acts as a ai, so there is no need for it. Clomid and Nolvadex are both anti-estrogens belonging to the same group of triphenylethylene compounds. They are structurally related and specifically classified as selective estrogen receptor modulators (SERMs) with mixed agonistic and antagonistic properties. This means that in certain tissues they can block the effects of estrogen, by altering the binding capacity of the receptor, while in others they can act as actual estrogens, activating the receptor. In men, both of these drugs act as anti-estrogens in their capacity to oppose the negative feedback of estrogens on the hypothalamus and stimulate the heightened release of GnRH (Gonadotropin Releasing Hormone). LH output by the pituitary will be increased as a result, which in turn can increase the level of testosterone by the testes.

Here is a bit of info from Heavyiron about why some employ Aromasin during PCT. It works for me, and it makes sense to try to keep the estrogen to testosterone balance in favor of testosterone during PCT. Like the fact that it improves free testosterone so dramatically.

Aromasin

(Exemestane)


Aromasin is a steroidal aromatase inactivator used to lower circulating estrogen. It was developed to help fight breast cancer as estrogen plays a role in the growth of cancer cells. Aromasin binds irreversibly to the aromatase enzyme. This suppresses the conversion of androgens into estrogen. Circulating estrogen can be reduced by nearly 85% in women using Aromasin. A common misconception is that aromatase inhibition is similar in men than women. However in trials when males were administered 25mg of Aromasin daily maximal estradiol suppression of 62 ± 14% was observed at 12 hours. Aromasin acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." In other words, Exemestane, by being structurally similar to the target of the enzymes, permanently binds to those enzymes, thereby preventing them from ever completing their task of converting androgens into estrogens. When we compare this mode of action against other AI’s the benefit becomes clear. Arimidex can unbind from the aromatase enzyme when you stop taking it but Aromasin will not therefore there is less chance of estrogen rebound with Aromasin.

Aromasin can be employed during a steroid cycle when aromatizing compounds such as testosterone are administered in order to control estrogen from getting out of control. During the course of a typical steroid cycle estrogen can rise quite high. Estrogen has been measured as much as 7 times higher than normal in men on steroids. This is excessive and can potentially cause water retention, gynecomastia (the formation of female breast tissue) or benign prostatic hyperplasia. Therefore in order to avoid these side effects estrogen must be controlled.

Aromasin not only lowers circulating estrogen and sex hormone binding globulin but it also increases free testosterone by a whopping 117%! Total testosterone increases about 60%. Check out the performance of Aromasin after just 10 days of treatment in males.

http://www.steroid.com/images/aromasin01.gif
FIG. 1. Estrogen and androgen plasma levels after 10 d of daily exemestane (25 or 50 mg) in healthy young males (mean ± SD; n = 9–11). To convert to Systeme International units: estradiol, picomoles per liter (x3.671); estrone, picomoles per liter (x3.699); androstenedione, nanomoles per liter (*0.003492); and testosterone, nanomoles per liter (x0.03467).

Aromasin may be used during a steroid cycle with aromatizing compounds and during PCT to help keep the estrogen to testosterone balance in favor of testosterone. Out of all the medications to control estrogen, Aromasin seems to be the most well balanced. It raises testosterone slightly better than Arimidex and lowers estradiol about 12% better than arimidex in men and is likely to cause less estrogen rebound than Arimidex. Keep in mind that 50mg of Aromasin daily kept estradiol in the normal range for men so if you think using an aromatase inhibitor will crush estrogen too much this science supports the opposite. From the data I have read and my years of experience with this medication 25mg of Aromasin every other day is a good starting point on moderate doses of testosterone. If testosterone doses are raised then 25mg daily may be needed to control estrogen. Since either high and low estrogen can cause side effects such as low libido only labs can determine the appropriate dose of Aromasin.

Written by heavyiron