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Frontloading and why it's done

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    Frontloading and why it's done

    Front-loading steroid cycles
    Posted Jul.13, 2007 under 3.4 - Steroid Cycle Planning

    There is a lot of scrutiny regarding proper anabolic-androgenic steroid cycle structure for maximal muscle gains with minimal risks. Front loading is one practice gaining attention in the bodybuilding community. This process immediately elevates blood androgen levels. Front loading omits the customary delay of obtaining peak and stable blood levels by increasing the cycle’s front-end use.

    Athletes stumble onto AAS use while scavenging for further ways to promote a progressive strength training routine – especially bodybuilders and powerlifters. Strength athletes often search for ways to develop productive steroid cycling protocols by combining the clinical research that is available with personal experience; as well as gathering insight from others. Formal clinical trials analyzing anabolic steroids in sports and exercise are rare. The medical community perceives little application for large performance-enhancing amounts of AAS to treat disease – even though many athletes would argue poor performance is an adverse health condition. Mostly through trial and error, numerous informal studies and private research examines various steroid cycling methods and how they can present a positive impact on performance and body composition. This information is generally shared through social networks, to include using online messaging software.

    Steroid hormones meant for intramuscular injection have attached fatty (carboxylic) acid esters to delay the hormone’s actions. They create a slow-release depot within the muscle for sustained and even blood levels. Instead of being immediately metabolize, the parent hormone is steadily released for days, or weeks. The rate at which the hormone is released is based on the ester’s characteristics; such as length and weight. Commonly available heavy, long esters are: enanthate, cypionate or decanoate.

    Due to a slow release, when a steroid with an attached heavy ester is injected at routine intervals, peak plasma concentrations can take weeks to elevate and remain stable. This is why most users do not notice performance results with heavy esters until a few weeks into the AAS cycle. Plasma levels must first build up to significant amounts to support the events associated with gains in strength and muscle mass. The ester’s speed of release is typically documented by it’s associated half-life, the time it takes for half of the administered steroid to metabolize. Active lives are also published, indicating the estimated time for full absorption of the compound.

    Many bodybuilders and powerlifters have begun to omit the waiting period for peak blood levels with front loading. Most users report muscular gains are best made during the first several weeks of an anabolic steroid cycle; results dwindle after six to eight weeks of application. Immediately flooding the system with growth hormones makes the most of this sensitive period. Simply put: front loading gets the cycle started quicker – while the body is most receptive of growth cues. Also, a quicker onset can present an option for shorter cycle duration; resulting in less impact to the hypothalamic-pituitary-gonadal axis for easier post-cycle recovery of natural androgen production.

    Normally, the same drug administered during the cycle is used to front load. The perfect front-load can be accurately calculated for stable release using figures and charts, but it’s cumbersome. There is some simplified guidance for front loading a heavy-ester cycle. First, calculate weekly use; administering 250 milligrams of testosterone enanthate every three days is equal to 583 milligrams per week (250/3*7). Then, double the weekly use and administer that amount prior to the first half life from the first injection – around four days for testosterone enanthate. Alternatively, the same compound with a lighter ester can be used, such as acetate or propionate.

    Today, many users are starting to front-load steroid cycles every time a heavy ester is used – to eliminate delayed affects on body composition and strength. Many others merely jump start a cycle with orals or suspensions, drugs without an ester allow quick absorption. Either method will boost blood levels up quickly to fully exploit the early responsive period – a time when the body is primed for growth and will best use the hormonal signals for amplified muscle growth.

    According to basic pharmacology, a single dose of 250mg of testosterone enanthate will deliver the parent hormone at it’s highest values the first 10 days; around 31, 27, 23, 20, 18, 15, 13, 12, 10 and nine milligrams, respectfully. After 10 days, the amounts released become negligible. Repeated injections create an overlap that gradually builds up blood levels. Actual amounts are affected by the injection site and technique, personal differences in physiology and the sites body fat levels.

    The above cycle illustrates testosterone enanthate administered at 250 milligrams every three days; with and without a front load. The front loaded portion was accurately configured and applied with 500 milligrams on day one, 250 milligrams on day two, a day off and then 250 milligrams every third day for the cycle’s duration. The front load is 1000 milligrams within the first four days – almost twice the weekly administered amount (583mg). Blood testosterone volume is immediately elevated and reasonably stable the first week with the front load.

    Non-front-loaded administration did not elevate and stabilize blood levels until over three weeks after the cycle’s launch. This is why results normally don’t manifest themselves for many weeks without a proper front load.



    Check out this chart....


    /V
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    My own pharmacokinetic modeling suggests a pinning frequency of no less than twice per halflife.

    Assuming enanthate has a halflife of seven days (I can assume anything; it varies due to a number of factors), a dose of 500mg pinned as 250mg twice a week and a high-normal baseline androgen status.

    No frontload: 3 weeks to steady-state
    600mg frontload: < 1 week

    Rule of thumb: whatever your ester and dose, pin twice per halflife. Frontload with double this dose.
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    Thanks for the read V.
    And extra input by Built.

    Question
    When i comes to Test flu most people get test flu on week 3-5. [Long Esters]
    According to that chart thats when blood levels start to stabilize.

    Assuming that Test flu happens when blood level stabilize.
    Frontloading will may cause Test Flu the first week ?

    Only bring up this point as i read a few threads where guys where frontloading on Long Esters and where experiencing Test flu from week 1-3,
    Some cases right throw there cycle.

    I personally think there where other things that caused it.
    Anyone heard anything like this ?

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    Good info guys Thanks.

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    Frontload'n is truly old school and I love it. All this Dbol kickstart to every cycle is new age and has become gospel since come'n outta the first parrots mouth. I remember the old joke theres 3 ways to start a cycle
    1.a Frontload
    2 a Truckload
    3. a Shitload
    or as an old friend says " the magic began with a gram"
    lolol Great post Vic.

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    Always been a fan of the frontload
    TheCaptn' is not a registered proctologist. His post are for his amusement only. Please seek proper medical advice if symptoms persist.


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    Quote Originally Posted by Supermans Daddy View Post
    Frontload'n is truly old school and I love it. All this Dbol kickstart to every cycle is new age and has become gospel since come'n outta the first parrots mouth. I remember the old joke theres 3 ways to start a cycle
    1.a Frontload
    2 a Truckload
    3. a Shitload
    or as an old friend says " the magic began with a gram"
    lolol Great post Vic.

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    Great information and now in my google docs. Excellent thread.



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    Always appreciate good info from experienced vets and gurus. It helps us all get the most out of our cycles and make better informed decisions.

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    I have tried frontloading numerous times with very little added effect. Muscle just plain takes time to grow so I am not sure much happens in the first few weeks of a cycle other than increased water retention and glycogen storage. I would say overall frontloading brought on strength gains about 1 week earlier when I tried it so instead of the profound gains I would normally see on week 5 I might see them around week 4 with enanthate or cypionate. This seems like a waste of gear especially since gains are going to happen anyway but whatever works for guys is fine by me.
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    What is an example of a frontload for cyp

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    That depends on the desired dose. If I was doing a gram per week of Cyp I would do something like this;

    day 1-1 gram
    day 2-500mg
    every 3 days after that 500mg per inject.

    btw, the guy who wrote the original post is a friend of mine. His screen name is Warrior. Very bright guy.

    http://www.warriorfx.com/2007/07/fro...teroid-cycles/
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    Quote Originally Posted by heavyiron View Post
    I have tried frontloading numerous times with very little added effect. Muscle just plain takes time to grow so I am not sure much happens in the first few weeks of a cycle other than increased water retention and glycogen storage. I would say overall frontloading brought on strength gains about 1 week earlier when I tried it so instead of the profound gains I would normally see on week 5 I might see them around week 4 with enanthate or cypionate. This seems like a waste of gear especially since gains are going to happen anyway but whatever works for guys is fine by me.
    So basically, pinning with more in the front of the cycle is merely water gain and glycogen?



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    Quote Originally Posted by juggernaut View Post
    So basically, pinning with more in the front of the cycle is merely water gain and glycogen?
    Check out the graph...


    /V

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    not a fan of front loading especially for enanthate since it takes so long to kicki n anyway.

    i say just do an oral kicker until the E kicks in.
    www.JackedFuture.com ! Check it out!

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    Quote Originally Posted by juggernaut View Post
    So basically, pinning with more in the front of the cycle is merely water gain and glycogen?
    Well frontloading does get blood androgen levels up faster and makes them more stable right away as well. The question is, how does that higher blood androgen level translate into actual muscle gain?
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    I will add another article.. this is a good thread!

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    Proper Dosing and Frontloading using the Principles of Half-Life’s

    By SuperDuty


    I’ve decided to write this article in regards to a great post made by Got Gear. He simply stated that at no time during a cycle will your test levels reach above 500mg a week if you’re taking 500mg a week of test enanthate. This is so very true and a lot more detailed than you probably think. This is what we base our dosages on since the onset and peak of most AAS is/are not established. The definition of half-life in regards to biology and pharmacology is simply the time required by the body, tissue, or organ to metabolize or inactivate half the amount of a substance taken in (Taber’s Cyclopedic Medical Dictionary). These principles are used for all medications, not just AAS. I’m going to break this down to the simplest form I can so bare with me because it may get a little confusing.

    The key thing to remember when it comes to half-life’s is that they will always be reduced by half of what’s remaining on a proportional and timely basis.

    I’m going to use Testosterone Cypionate as my example in this demonstration since it is a commonly used AAS for beginners and pros alike.
    Testosterone Cypionate half-life is 8 days (Davis’s Drug Guide for Nurses 9th Ed.)

    500mg Test Cyp every 8 days
    Day 1 – 500mg (remember that the bioavailability at this point is 0 because it takes 8 days to metabolize 250mg, and this will be true for every dose that follows)

    Day 9 – 500mg (remember what was stated on day 1), so at this point you have 250mg remaining in the body from day 1 because your body has used 250mg over the past 8 days)

    Day 17 – 500mg, at this point you have 250 from Day 9 and 125 from day 1 (don’t confuse yourself here, the body does not process 250mg every 8 days, it simply reduces the remaining by half every 8 days)

    Day 25 – 500mg, at this point you have 250mg from Day 17, 125 from Day 9, and now just 62.5 remaining from day 1

    Day 33 – 500mg, at this point you have 250mg from Day 25, 125 from Day 17, 62.5 from Day 9, and 31.7 from day 1.

    The easy way to keep going on with this formula is to take the smallest number (31.7 in this case) and reduce it by half, then add it to your existing numbers for the total, and then repeat.

    The total looks like this:
    The first 8 days your body will metabolize 250mg
    The second 8 days your body will metabolize half of the remaining 250 (125) and half of the 500 (250) administered on day 9 for a total of 375.
    The third 8 days your body will metabolize 250, 125, and 62.5 for a total of 437.5. This is one reason it takes a couple of weeks to start noticing the effects of this drug.
    To keep figuring out the bioavailability just keep reducing your smallest number by half and adding it to the total as described earlier.

    Here is a chart demonstrating the bioavailability and how long it takes to even reach that 500mg per 8 day mark. For this demonstration we will use 8 days for 1 wk.
    Wk 1 – 250mg
    Wk 2 – 375mg
    Wk 3 – 437.5mg
    Wk 4 – 469.2mg
    Wk 5 – 485mg
    Wk 6 – 492.9mg
    Wk 7 – 496.8mg
    Wk 8 – 498.7mg
    And so on….

    So what does all this mean? Well for one it brings up a very important issue of frontloading. To frontload, you simply double your weekly dose just for that first week. It would look like this:
    Wk 1 – 1000mg Cyp
    Wk 2 – 500mg Cyp
    Wk 3 – 500mg Cyp
    And continue on at the normal 500mg/wk

    The way this works is simple, during week 1 your body will metabolize 500mg of the first dose leaving you with 500 remaining. The second week your body will metabolize 250mg from the first dose and also 250 from the second dose for a total of 500. Now do you see how beneficial frontloading really is? You will stay constant at 500mg/wk throughout your cycle instead of tapering up by not frontloading.

    All that has been described in this post is hypothetically based on the principles of half-life’s. Nevertheless, this should give you a general idea of how much your body is using in any one given week. This holds true for every AAS and medication there is, after all that’s what medication administration is based on so don’t argue with me about this, argue with science and the millions of doctors who actually get paid to come up with this stuff.

    Also, on a side note, I’ve noticed quite a few boards that vary on half-lifes for certain AAS such as Cyp, most state the half-life as being around 10 days. I’m in no way saying this is wrong but I tend to get and base as much information as possible on medical articles and websites. I have found the half-life of cyp to be 8 days both in a nursing book and also on drug.com. The only catch to this is that some, in fact most AAS are not evaluated, published, or even talked about in the medical field so your on your own on that one.

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    What about front loading your test e with test p?

    What would be the formula for that?

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    I just ran some quick models: Assuming a high-normal starting point, 600mg test cyp pinned twice a week will take about 6 weeks to stabilize - assuming an 8-day halflife on the cyp and 2 days for the prop (halflife varies depending upon the size of the shot, the oil used, the concentration of the active, the muscle pinned and your own metabolism).

    Cyp is about 69% testosterone
    Prop is about 79% testosterone (lighter ester than cypionate)

    If you just happen to have some prop handy, you can use prop to bring up your levels by pinning it alongside your cyp. This is really approximate, but should do you justice:

    Week 1: 200 test cyp, 200 prop Mon, Wed, Sat
    Week 2: 200 test cyp, 150 prop Mon, Wed, Sat
    Week 3: 200 test cyp, 125 prop Mon, Wed, Sat
    Week 4: 200 test cyp, 100 prop Mon, Wed, Sat
    Week 5: 200 test cyp, 75 prop Mon, Wed, Sat
    Week 6: 200 test cyp, 50 prop Mon, Wed, Sat

    By then, you should be good to go at two shots of 300mg test cyp per week.
    Last edited by Built; 05-08-2011 at 05:53 PM.
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    Quote Originally Posted by heavyiron View Post
    I have tried frontloading numerous times with very little added effect. Muscle just plain takes time to grow so I am not sure much happens in the first few weeks of a cycle other than increased water retention and glycogen storage. I would say overall frontloading brought on strength gains about 1 week earlier when I tried it so instead of the profound gains I would normally see on week 5 I might see them around week 4 with enanthate or cypionate. This seems like a waste of gear especially since gains are going to happen anyway but whatever works for guys is fine by me.
    Heavy do you still agree with this statement you made 6 months ago about frontloading? Just curious because of your recent massive frontload!

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