Thread: prevent or cure gyno?

The medications you are referring to are called Aromatase inhibitors.
Aromatase is an enzyme. This enzymes function is to convert testosterone into estrogen.
An aromatase inhibitor binds to this enzyme therefore preventing testosterone from binding to it and as a result preventing the enzymatic conversion of testosterone to estrogen.
They will not cure gyno.
An AI (aromatase inhibitor) is used to keep estrogen in check during cycles containing aromatising AAS and to ensure low levels of estrogen leading into PCT and thus making the PCT more efficient and as a result the whole cycle more successful.

The only cure for gyno is to get it chopped out. My buddy got it done and it's free in Canada plus he got 2 weeks off work to recover!

Originally Posted by D-Latsky

The only cure for gyno is to get it chopped out. My buddy got it done and it's free in Canada plus he got 2 weeks off work to recover!

Yup, AI's can shrink existing gyno, however getting rid of it all together is all together different.

thanx guys makes alot more sence now

An Ai is best used as a preventative measure.
When estro is low gyno is rare.
If gyno symptoms should arise, starting an AI will help but Tamoxifen works better for shrinking lumps.

[Influence of size and duration of gynecomastia on its response to treatment with tamoxifen]

[Article in Spanish]
Devoto C E, Madariaga A M, Lioi C X, Mardones N.
Sección Endocrinología, Servicio de Medicina, Hospital Clínico San Borja Arriarán, Santiago, Chile. edevoto@vtr.net

Abstract

BACKGROUND: Gynecomastia is treated when it is painful, there are psychosocial repercussions or it does not revert in less than two years. It is treated with the antiestrogenic drug tamoxifen, but there are doubts about its effectiveness in high volume gynecomastias or in those lasting more than two years.

AIM: To assess the effectiveness and safety of tamoxifen for gynecomastia and the influence of its volume and duration on the response to treatment.

PATIENTS AND METHODS: Forty three patients with gynecomastia, aged 12 to 62 years, were studied. Twenty seven patients had a pubertal physiological gynecomastia, in eight it was caused by medications, in four it was secondary to hypogonadism, in three it was idiopathic and in one it was due to toxic exposure. Twenty patients had mastodynia and in 33, gynecomastia had a diameter over 4 cm. It lasted less than two years in 30 patients, more than two years in nine and four did not recall its duration. All were treated with tamoxifen 20 mg/day for 6 months. A follow up evaluation was performed at three and six months of treatment.

RESULTS: Mastodynia disappeared in all patients at three months. At six months gynecomastia disappeared in 26 patients (62%), but relapsed in 27%. All gynecomastias caused by drugs with antiandrogen activity disappeared. Fifty two percent of gynecomastias over 4 cm and 90% of those of less than 4 cm in diameter disappeared (p<0.05). Fifty six percent of gynecomastias lasting more than two years and 70% of those of a shorter duration disappeared (p=NS). Two patients had diarrhea or flushes associated to the therapy.

CONCLUSIONS: Tamoxifen is safe and effective for the treatment of gynecomastia. Larger lesions have a lower response to treatment.

The medications you are referring to are called Aromatase inhibitors.
Aromatase is an enzyme. This enzymes function is to convert testosterone into estrogen.
An aromatase inhibitor binds to this enzyme therefore preventing testosterone from binding to it and as a result preventing the enzymatic conversion of testosterone to estrogen.
They will not cure gyno.
An AI (aromatase inhibitor) is used to keep estrogen in check during cycles containing aromatising AAS and to ensure low levels of estrogen leading into PCT and thus making the PCT more efficient and as a result the whole cycle more successful.

Great right up.

Thanks brother.

Im not sure if you are looking for a prevention method, or a cure after it forms, but this is a good read: 16 Ways to Fight Gyno Sorry for the google cache, are site is down until tomorrow while we prepare for the androseries launch.

Originally Posted by HereToStudy

Im not sure if you are looking for a prevention method, or a cure after it forms, but this is a good read: 16 Ways to Fight Gyno Sorry for the google cache, are site is down until tomorrow while we prepare for the androseries launch.

Great article covering many options

Originally Posted by D-Latsky

The only cure for gyno is to get it chopped out. My buddy got it done and it's free in Canada plus he got 2 weeks off work to recover!

even surgery is not a guaranteed "cure". Gyno can still come back after surgery.

OP, try tamoxifen.

Originally Posted by bmw

even surgery is not a guaranteed "cure". Gyno can still come back after surgery.

OP, try tamoxifen.

True. I wonder if using a SERM/AI post-op would help prevent gynecomastia recurrence.

Guys, I thought gyno wouldn't come back if you had the gland removed as well as the excess tissue???

Originally Posted by brundel

The medications you are referring to are called Aromatase inhibitors.
Aromatase is an enzyme. This enzymes function is to convert testosterone into estrogen.
An aromatase inhibitor binds to this enzyme therefore preventing testosterone from binding to it and as a result preventing the enzymatic conversion of testosterone to estrogen.
They will not cure gyno.
An AI (aromatase inhibitor) is used to keep estrogen in check during cycles containing aromatising AAS and to ensure low levels of estrogen leading into PCT and thus making the PCT more efficient and as a result the whole cycle more successful.

Very well said. Very clear.

1 question about gyno is it fat deposit around the nipple or is it a gland that grows size?

Transdermal preparations of DHT are helpful if your gyno isn't "seasoned".

Your best bet is to prevent it. Once it starts your fucked!

Originally Posted by Roughneck_91

Transdermal preparations of DHT are helpful if your gyno isn't "seasoned".

Correct, DHT shows benefits in this area.