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Do dosages affect PCT start time?

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    Do dosages affect PCT start time?

    I was ALWAYS under the assumption that the only thing that determined PCT start time is the ester of the compound you're running. I've been told by someone who I assumed knew what they were talking about that it would take right around a month for 1g of Test-E to clear. I'd never heard that before and kind of had a WTF moment.

    It's 2 weeks after the last test-e shot that PCT should begin correct?

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    Most people will say 2 weeks after last shot of a test e, but this is based on a dose of about 500mg/week (I believe). The higher the dose the longer it takes for enough test to clear your system so that you can even attempt to bring back your natural systems.

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    Yes you are correct. You would begin PCT between 10-14 days after last inject.








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    Now there's conflicting info in my thread!

    **Nerd Herd Alert**


    I'm going to think out loud here and MAYBE I'll be correct. But I'm probably wrong so someone please correct me and tell me that it's only 14 days. Cause that's what I've been planning on.

    I can see why it would take longer. Because the half life is exactly that. Half of the life of that specific dose. I believe the half life of test-E is 10.5 days. So if I calculated this the correct way that means at 500mg that's 23.81mg's that's your losing per day. At 14 days that would put you at about 166.66mg to start PCT.

    So at 1g per week, using the same method I used above, you would "lose" 47.61mg per day. So at that ratio it would take 17.5 days for the levels to reach the same 166.66.

    This is probably wrong because I don't think you would lose a fixed amount of test per day. I believe it would be based on the "remaining" test in your system compared to the half life of the compound. It would be more of an exponential curve compared to a straight declining line.


    **End of Nerd Herd Alert**



    Someone please sort this out for us.

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    Since we are on the nerd herd...your calculations are off to begin with because 1000mg of Test E is only around 680mg of actual test, as the enanthate ester only yields about 68%.

    Start you PCT on day 14, and you will be fine my friend.

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    Quote Originally Posted by GMO View Post
    Since we are on the nerd herd...your calculations are off to begin with because 1000mg of Test E is only around 680mg of actual test, as the enanthate ester only yields about 68%.

    Start you PCT on day 14, and you will be fine my friend.

    I agree








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    Awesome. I knew there wasn't something correct about it. But I talked myself into thinking that maybe something was wrong with my PCT.

    Carry on.

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    Quote Originally Posted by GMO View Post
    Since we are on the nerd herd...your calculations are off to begin with because 1000mg of Test E is only around 680mg of actual test, as the enanthate ester only yields about 68%.

    Start you PCT on day 14, and you will be fine my friend.
    Sounds right to me.

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    Quote Originally Posted by tgb1987 View Post
    yes you are correct. You would begin pct between 10-14 days after last inject.
    +1.

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    Quote Originally Posted by GMO View Post
    Since we are on the nerd herd...your calculations are off to begin with because 1000mg of Test E is only around 680mg of actual test, as the enanthate ester only yields about 68%.

    Start you PCT on day 14, and you will be fine my friend.
    Do you have any links on where you got this information? I'd love to know more.

    Thanks.

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    It's all over the place man. 1st link on a google search:

    "There is however one way that we can say an ester does technically effect potency; it is calculated in the steroid weight. The heavier the ester chain, the greater is its percentage of the total weight. In the case of testosterone enanthate for example, 250mg of esterified steroid (testosterone enanthate) is equal to only 180mg of free testosterone. 70mgs out of each 250mg injection is the weight of the ester. If we wanted to be really picky, we could consider enanthate slightly MORE potent than cypionate (I know this goes against popular thinking) as its ester chain contains one less carbon atom (therefore taking up a slightly smaller percentage of total weight). Propionate would of course come out on top of the three, releasing a measurable (but not significant) amount more testosterone per injection than cypionate or enanthate."

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    have to disagree, it may not make a huge difference until you start getting to pretty high dosages but you can figure it out with the half life. We'll start with 1g test E which is apparently 680mgs of test, also assuming 10.5 day half life

    680mgs starting-10.5 days later we have 340mgs
    340 10.5 days later we have 170mgs.
    170mg - 10.5days = 85mgs

    so now we're at 30days already before we get to the point that the release rate will probably be lower than your normal test production. When your body senses it will produce just that little extra test to make up the difference (or it will begin trying at least). Imo this is the point that you would want to begin pct. Even @ 500mg there will still be some small amount of test floating around @2 weeks, but as far as I know once you're no longer at supraphysiological levels your hpta will begin to wake back up especially if you introduce a serm. Your test levels don't have to hit zero to start pct they just have to be lower than your body thinks is right (estrogen plays a large part in this as well obviously so an AI should be used all the way up to pct or even all the way through).

    Does this make sense or am I way off?
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    Yes that does make sense. Though I am fairly certain half life of enanthate is 5.25 days.

    Ill give an example. My son is on Adderall XR. He takes it around 7 am before school. His dosage for a long time was 10 mg. By 5:30 pm however it would be inactive and when he is at Karate, he would become very distractive to the class.

    The doctor increased his dose to 15 mg, and explained that although the half life remains the same, because of the higher dosage, when 5:30 comes there would still be enough active medication still circulating to help.

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    Hold up brother. These half lives are based on enzymatic metabolism of these drugs, (ester is enzymatically cleaved, and the hormone is enzymatically degraded to metabolites that can be urinated out) which can vary greatly from person to person, and can be induced or inhibited by other drugs, or higher concentrations of the same drug. 10 grams of test injected into you at one time will take a much longer time for your body to break down than 1 gram. Dose definitely affects clearance time, but it is not an exact science and I am not sure that anyone has done a study on elimination time for 1 gram of test injected at one time. Half lives are designed with the expectation that they will repeat, and concentrations will ramp down little by little for the duration of multiple half lives. It's not 500 mg one week 500 the next. Also the size of the depot and rate of spreading makes a difference. That said, I honestly don't know how long you should wait. At best base it on what's worked for other people that have recovered their levels after using high doses. Good luck brother.

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    I've heard dr scally say that high doses of test will keep levels elevated for 30 days.
    But, it doesn't hurt anything to start your serm treatment while your levels are still elevated.
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    If you're starting pct while levels are still high do you think it'd be a good idea to run a longer pct? If your test is still high for the first two weeks of pct do they even count?
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    Quote Originally Posted by SloppyJ View Post
    I was ALWAYS under the assumption that the only thing that determined PCT start time is the ester of the compound you're running. I've been told by someone who I assumed knew what they were talking about that it would take right around a month for 1g of Test-E to clear. I'd never heard that before and kind of had a WTF moment.

    It's 2 weeks after the last test-e shot that PCT should begin correct?
    I always start a little early. It doesn't hurt to have the SERM in place already when the androgens run low enough to restart the system. If anything that will help get things going a little sooner. I start with a low dose of Clomid and add in Nolvadex after 10 days to 2 weeks. Then I phase out Clomid and stay on Nolvadex. The whole thing takes 4-6 weeks. 6 weeks if longer esters and larger doses are used. That should be plenty of time.

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