how does it "fit" into the receptor? From that pic it looks like its just kinda floating there and its shape doesn't seem like it matches up with the receptor site. Maybe a dumb question but I kind of always pictured receptors like puzzle pieces that fit the molecule, how does it really work?
Originally Posted by Glycomann
no it's the gray ringy thing that looks like this..
how does it "fit" into the receptor? From that pic it looks like its just kinda floating there and its shape doesn't seem like it matches up with the receptor site. Maybe a dumb question but I kind of always pictured receptors like puzzle pieces that fit the molecule, how does it really work?
If I represented the receptor as it's true space filled form with all its volume including all side chains you would not be able to see the steroid molecule in its receptor site. As it is represented the testosterone molecule is in it's correct position and orientation according to the X-ray crystalographic data that was used to create the image. Here is the space filled representation.
gotcha, so how does it get inside? Or am I missing something that makes this another stupid question lol
Originally Posted by Glycomann
If I represented the receptor as it's true space filled form with all its volume including all side chains you would not be able to see the steroid molecule in its receptor site. As it is represented the testosterone molecule is in it's correct position and orientation according to the X-ray crystalographic data that was used to create the image. Here is the space filled representation.
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