Thread: Using myostatin blockers to grow?

Using myostatin blockers to grow?

Add clen and you'll grow more

Chemical athletes and their gurus in the doping world have high hopes for myostatin blockers that pharmaceutical companies are testing right now on people with cancer or muscular diseases. Their hopes are well founded – animal studies have shown that myostatin blockers can cause massive growth of muscle mass. But yet another animal study, soon to be published in Muscle & Nerve, suggests that the combination of a myostatin blocker and an old-school doping substance like clenbuterol results in even more growth.

Clenbuterol

Myostatin is a muscle protein that keeps muscle growth in check. Myostatin blockers deactivate the protein and its effect. Because myostatin is active pretty much only in the muscles and nowhere else, scientists hope that myostatin blockers will be the long hoped-for anabolic without side effects. Time will tell whether their hopes are justified. In animal studies blocking myostatin has reduced stamina, and weakened muscle attachments.

Researchers don't yet agree on how best to deactivate myostatin. Pharmaceuticals companies like Acceleron are doing tests on synthetic imitation receptors that replace and neutralise myostatin. Another approach is to boost follistatin synthesis. Follistatin is a protein that deactivates myostatin in the muscle cells. Yet another approach makes use of the immune system.

Chinese agricultural researchers for example are looking at the possibility of injecting massive quantities of myostatin. These may well lead to muscle tissue breakdown in the short term, but in the long term the immune system would come to regard myostatin as a foreign substance that the body needs to break down.

The study that molecular scientists at the University of Hawaii will publish soon is fundamental research. The authors used mice in which the myostatin gene had been deactivated – a bit like Mighty Mouse. The muscles of this type of mice are shown in the lower of the two photos at the top of the page. The top photo shows the muscles of a normal mouse. The researchers wanted to know whether these supermice could develop even bigger muscles by giving them a doping substance like clenbuterol [structural formula shown above]. And yes, it worked.

M = myostatin-less mice, W = normal mice. 0 ppm = no clenbuterol, 20 ppm = with clenbuterol.

Originally Posted by BigBird

Anybody read about the German baby born without the myostatin gene? I think he was raising 5lb dumbbells over his head at 10 months old. He's a toddler right now I believe. His quads are like Giant Redwood trees. Not sure if and how his long term health is/will be affected but keep close tabs on him as it's very interesting to see him develop from SuperBoy into Superman - no aas required.

Yes, I saw that a couple months ago. He is freakishly strong for his age and I hope he takes advantage of it with sports through the years!