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    T3 Question

    This is my first time using T3. Right now I am taking a 12.5 mcg dose ED. Is this a good dose to increase my hormone level while not shutting down my own thyroid? I couldn't find any information on what dose negative feedback begins to occur.

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    Nobody knows?

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    Over 75mcg/ED.
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    So I can take up to 75 mcg before it shuts down my natural thyroid hormone production? That seems really high. I thought I read 50 mcg is a replacement dose?

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    Most of these things work like this. Your body produces some amount, say amount X, that it thinks it needs. Now you start supplementing with amount Y. Well, your body doesn't think it needs X+Y, it only needs X, but you're giving it Y so it only needs to produce the difference (X-Y). In other words, if your body naturally produces 25 mcg/day and you add 12.5 mcg/day then you now only need to produce and addtional 12.5/day to get back to the original 25 mcg/day. Thus, adding less than your body produces adds nothing to the total. To get the benefit from hormone supplementation, you generally must take more than your body would produce on its own, and you have to shut down natural production to gain any benefit. That's the inherent problem that we here all have to deal with.

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    Quote Originally Posted by BGOTTIR View Post
    So I can take up to 75 mcg before it shuts down my natural thyroid hormone production? That seems really high. I thought I read 50 mcg is a replacement dose?
    Replacement doses vary. I take 125 mcg daily because I had a partial thyroidectomy 35 years ago. Dialing in what your body needs is not a quick thing, requires lab work, usually need to take medication a few months and then get lab work to see if the dose is right, this could go on for a while until they find the right dose for you. Hope this helps.

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    Hmmmmm...I understand what you guys are saying, just not what I wanted to hear. What you said seems logical Once, I was just hoping the negative feedback mechanism for thyroid hormone production was different somehow.

    After a little more research today through Google, I found some conflicting reports: some said T4 is what signals the inhibition of TSH (thyroid stimulating hormone), and T3 to a very small degree. Others, however, stated it is T3 and T4 that contribute to negative feedback. Anyone heard about this?

    *Sorry by the way for my attempt to figure out the details. I am very scientifically minded (and educated), and I feel the need to know everything about this kind of shit.

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    Do not take t3 if you are not using AAS because you will loose a shit load of muscle.
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    Quote Originally Posted by Imosted View Post
    Do not take t3 if you are not using AAS because you will loose a shit load of muscle.
    agree^^

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    I just started the T3 and my first "advanced cycle" on Monday. With the amount of gear I am on, my diet and my training, there is no way in hell I will lose muscle!

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