Thread: Why is it I see test c mostly recommend for TRT?

prolly for the half life?

yeah...think c last a couple more days that e

Test c has a half life of 2 more days then test e.

Sent from my phone.

Bro, love you to death, but please dont post info you arent 100% sure about.

Originally Posted by GymRat4Life

Test c has a half life of 2 more days then test e.

Sent from my phone.

Enanthate: Chemical Structure C7H14O2.
Also referred to as heptanoic acid; enanthic acid; enanthylic acid; heptylic acid; heptoic acid; Oenanthylic acid; Oenanthic acid. Enanthate is one of the most prominent esters used in testosterone manufacture (most commonly seen with testosterone but is also used in other compounds like primobolan Depot). Enanthate will release a steady (yet fluctuating as all esters are) level of hormone for approximately 10-14 days. Although in medicine enanthate
compounds are often injected on a bi-weekly or monthly basis, athletes will inject at least weekly to help maintain a uniform blood level.

Cypionate: Chemical Structure C8H14O2.
Also referred to as Cyclopentylpropionic acid, cyclopentylpropionate. Cypionate is a very popular ester here in the U.S., although it is scarcely found outside this region. Its release duration is almost identical to enanthate (10-14 days), and the two are likewise thought to be interchangeable in U.S. medicine. Althletes commonly hold the belief than cypionate is more powerful than enanthate, although realistically there is little difference between the two. The enanthate ester is in fact slightly smaller than cypionate, and it therefore releases a small (perhaps a few milligrams) amount of testosterone more in comparison.

I could have swore I've read it was 2 days, even told that by some high repped members here. Damn.

Its a pretty common misinformation, a lot of people believe that because of what others who have no idea what their talking about have said

Originally Posted by GymRat4Life

I could have swore I've read it was 2 days, even told that by some high repped members here. Damn.

Test C = America/Canada

Test E = Europe/Asia

Test C = Six (6)

Test E = half dozen

Catch my drift?

Same question would be asked if US TRT was Test E as opposed to Enanthate. It's gotta be one so why not the other.

My doc prescribed me Test E from a good USA pharm. Almost all of the info i have read, state that the half life for Test E is 10 to 14 days.

Ooops just read the box my test came in, and it says made in Canada...

Originally Posted by GymRat4Life

I could have swore I've read it was 2 days, even told that by some high repped members here. Damn.

Half Life's are not an exact science. But for All intents and purposes you are in fact correct.

Originally Posted by TwisT

Bro, love you to death, but please dont post info you arent 100% sure about.



Enanthate: Chemical Structure C7H14O2.
Also referred to as heptanoic acid; enanthic acid; enanthylic acid; heptylic acid; heptoic acid; Oenanthylic acid; Oenanthic acid. Enanthate is one of the most prominent esters used in testosterone manufacture (most commonly seen with testosterone but is also used in other compounds like primobolan Depot). Enanthate will release a steady (yet fluctuating as all esters are) level of hormone for approximately 10-14 days. Although in medicine enanthate
compounds are often injected on a bi-weekly or monthly basis, athletes will inject at least weekly to help maintain a uniform blood level.

Cypionate: Chemical Structure C8H14O2.
Also referred to as Cyclopentylpropionic acid, cyclopentylpropionate. Cypionate is a very popular ester here in the U.S., although it is scarcely found outside this region. Its release duration is almost identical to enanthate (10-14 days), and the two are likewise thought to be interchangeable in U.S. medicine. Althletes commonly hold the belief than cypionate is more powerful than enanthate, although realistically there is little difference between the two. The enanthate ester is in fact slightly smaller than cypionate, and it therefore releases a small (perhaps a few milligrams) amount of testosterone more in comparison.

This looks familiar...Im pretty sure Ive read that post several years back. However, Ive got dozens more studies and links to support actual half life difference is between 1-2.5 days

Tried them both, like them both. My trt doc scrip lets me get 10ml a month, nice base to have on hand for blast/cruise

Originally Posted by Mr.BIG

Test C = America/Canada

Test E = Europe/Asia

This.

Originally Posted by Ace5high

This looks familiar...Im pretty sure Ive read that post several years back. However, Ive got dozens more studies and links to support actual half life difference is between 1-2.5 days

Please post them, I would love to read them.

Originally Posted by CT

Please post them, I would love to read them.

LOL, me too...

my DR has me on DELATESTRYL aka enathate

Really Guys? This is basic info...

Below a list of half-life's of the most commonly used steroids, esters and ancillary compounds.
Oral steroids Drug Active half-life
Anadrol / Anapolan50 (oxymetholone) 8 to 9 hours
Anavar (oxandrolone) 9 hours
Dianabol (methandrostenolone, methandienone) 4.5 to 6 hours
Winstrol (stanozolol)
(tablets or depot taken orally) 9 hours
Depot steroids Drug Active half-life
Deca-durabolin (Nandrolone decanate) 14 days
Equipoise 14 days
Finaject (trenbolone acetate) 3 days
Primobolan (methenolone enanthate) 10.5 days
Sustanon or Omnadren 15 to 18 days
Testosterone Cypionate 12 days
Testosterone Enanthate 10.5 days
Testosterone Propionate 4.5 days
Testosterone Suspension 1 day
Winstrol (stanozolol) 1 day
Steroid esters Drug Active half-life
Formate 1.5 days
Acetate 3 days
Propionate 2 days
Phenylpropionate 4.5 days
Butyrate 6 days
Valerate 7.5 days
Hexanoate 9 days
Caproate 9 days
Isocaproate 9 days
Heptanoate 10.5 days
Enanthate 10.5 days
Octanoate 12 days
Cypionate 12 days
Nonanoate 13.5 days
Decanoate 15 days
Undecanoate 16.5 days
Ancillaries Drug Active half-life
Arimidex 3 days
Clenbuterol 1.5 days
Clomid 5 days
Cytadren 6 hours
T3 10 hours
Active Life versus Half Life
The confusion comes from the 2 terms being used synonymously when they should not be. "Half-life is not a reference for the total time a drug will be found active in the body. It may take several half-lives before the drug is completely inactive."
Half-life: The period of time required for the concentration or amount of drug in the body to be reduced to exactly one-half of a given concentration or amount.
Example: The half-life of anavar is 9 hours+/- (9 hours after oral administration of 50 mg of anavar, 25mg is still present in the body).
Active life: Refers to the period in which the amount of a drug in the body is enough that it will still produce the desired effects for which it was administered. Or conversely, inhibit natural recovery of normal bodily function. It is dose dependent.
Example: The active life of 1,000mg of testosterone decanoate would be more than one month. At day 30 after injection, 250mg or more of this drug would still be present in the body.
WHAT AN ESTER IS, AND HOW IT WORKS
I'm sure that if you have taken an interest in anabolic steroids you have noticed the similarities on the labeling of many drugs. Let's look at testosterone for example. One can find compounds like testosterone cypionate, enanthate, propionate, heptylate; caproate, phenylpropionate, isocaproate, decanoate, acetate, the list goes on and on. In all such cases the parent hormone is testosterone, which had been modified by adding an ester (enanthate, propionate etc.) to its structure. The following question arises: What is the difference between the various esterified versions of testosterone in regards to their use in bodybuilding?
An ester is a chain composed primarily of carbon and hydrogen atoms. This chain is typically attached to the parent steroid hormone at the 17th carbon position (beta orientation), although some compounds do carry esters at position 3 (for the purposes of this article it is not crucial to understand the exact position of the ester). Esterification of an injectable anabolic/androgenic steroid basically accomplishes one thing, it slows the release of the parent steroid from the site of injection. This happens because the ester will notably lower the water solubility of the steroid, and increase its lipid (fat) solubility. This will cause the drug to form a deposit in the muscle tissue, from which it will slowly enter into circulation as it is picked up in small quantities by the blood. Generally, the longer the ester chain, the lower the water solubility of the compound, and the longer it will take to for the full dosage to reach general circulation.
Slowing the release of the parent steroid is a great benefit in steroid medicine, as free testosterone (or other steroid hormones) previously would remain active in the body for a very short period of time (typically hours). This would necessitate an unpleasant daily injection schedule if one wished to maintain a continuous elevation of testosterone. By adding an ester, injections can be as infrequent as once per week or longer, instead of having to constantly re-administer the drug to achieve the desried effect. Clearly without the use of an ester, maintaining constant blood levels with an injectable anabolic/androgen would be much more difficult.
Esterification temporarily deactivates the steroid molecule. With a chain blocking the 17th beta position, binding to the androgen receptor is not possible (it can exert no activity in the body). In order for the compound to become active the ester must therefore first be removed. This automatically occurs once the compound has filtered into blood circulation, where esterase enzymes quickly cleave off (hydrolyze) the ester chain. This will restore the necessary hydroxyl (OH) group at the 17th beta position, enabling the drug to attach to the appropriate receptor. Now and only now will the steroid be able to have an effect on skeletal muscle tissue.
You can start to see why considering testosterone cypionate much more potent than enanthate makes little sense, as your muscles are seeing only free testosterone no matter what ester was used to deploy it.
ACTIONS OF DIFFERENT ESTERS
There are many different esters that are used with anabolic/androgenic steroids, but again, they all do basically the same thing. Esters vary only in their ability to reduce a steroid's water solubility. An ester like propionate for example will slow the release of a steroid for a few days, while the duration will be up to 15 days+/- with a decanoate ester. Esters have no effect on the tendency for the parent steroid to convert to estrogen or DHT (dihydrotestosterone: a more potent metabolite) nor will it effect the overall muscle-building potency of the compound. Any differences in results and side effects that may be noted by bodybuilders who have used various esterified versions of the same base steroid are just issues of timing.
*Testosterone enanthate causes estrogen related problems more readily than Sustanon, simply because with enanthate testosterone levels will peak and trough much sooner. Likewise testosterone suspension is the worst in regards to gyno and water bloat because blood hormone levels peak so quickly with this drug (propionate included). Instead of waiting weeks for testosterone levels to rise to their highest point, here we are at most looking at a couple of days. Given an equal blood level of testosterone, there would be no difference in the rate of aromatization or DHT conversion between different esters. There is simply no mechanism for this to be possible.
There is however one way that we can say an ester does technically effect potency; it is calculated in the steroid weight. The heavier the ester chain, the greater is its percentage of the total weight. In the case of testosterone enanthate for example, 250mg of esterified steroid (testosterone enanthate) is equal to only 180mg of free testosterone. 70mgs out of each 250mg injection is the weight of the ester. If we wanted to be really picky, we could consider enanthate slightly MORE potent than cypionate (I know this goes against popular thinking) as its ester chain contains one less carbon atom (therefore taking up a slightly smaller percentage of total weight). Propionate would of course come out on top of the three, releasing a measurable (but not significant) amount more testosterone per injection than cypionate or enanthate.
IN CONCLUSION
While the advent of esters certainly constitutes an invaluable advance in the field of anabolic steroid medicine, clearly you can see that there is no magic involved here. Esters work in a well-understood and predictable manner, and do not alter the activity of the parent steroid in any way other than to delay its release. Although the lure surrounding various steroid products like testosterone cypionate, Sustanon, Omnadren etc. certainly makes for interesting conversation, realistically it just amounts to misinformation that the athlete would be better off ignoring. Testosterone is testosterone and anyone who is going to tell you one ester form of this (or any) hormone is much better than another one should do a little more research, and a lot less talking.
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Active half-life steroids:
DrugActive half-lifeAnadrol / Anapolan50 (oxymetholone)8 to 9 hoursAnavar (oxandrolone)9 hoursDianabol (methandrostenolone, methandienone)4.5 to 6 hoursMethyltestosterone4 daysWinstrol (stanozolol)9 hoursHalotestin (Fluoxymesterone)9.5 hoursTurinabol (Tbol)16 hours

Injectable steroids:
DrugActive half-lifeDeca-durabolin (Nandrolone decanate)15 daysEquipoise14 daysFinaject (trenbolone acetate)3 daysPrimobolan (methenolone enanthate)10.5 daysSustanon or Omnadren15 to 18 daysTestosterone Cypionate12 daysTestosterone Enanthate10.5 daysTestosterone Propionate4.5 daysTestosterone Suspension1 dayWinstrol (stanozolol)1 day

Steroid esters:
DrugActive half-lifeFormate1.5 daysAcetate3 daysPropionate4.5 daysPhenylpropionate4.5 daysButyrate6 daysValerate7.5 daysHexanoate9 daysCaproate9 daysIsocaproate9 daysHeptanoate10.5 daysEnanthate10.5 daysOctanoate12 daysCypionate12 daysNonanoate13.5 daysDecanoate15 daysUndecanoate16.5 days

Ancillaries:
DrugActive half-lifeArimidex3 daysClenbuterol1.5 daysClomid5 daysCytadren6 hoursEphedrine6 hoursT310 hoursLetrozole5 hoursNolvadex (Tamoxifen Citrate)14 days
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Active Half-life of Steroids and Esters
Updated June 2010 by PartyBoy, MuscleTalk Moderator
An important consideration when planning a steroid cycle, in particular the timing of dosing to be administered, is the active half-life of the drug being employed. The half-life may be defined as the time (t) the level is half of the starting level of a given compound; at time 2t, the level is a quarter of the starting level, and at time 3t, the level is an eighth of the starting level, and so on.
This information is vital in the timing of the dosing when attempting to achieve a more stable blood concentration, which leads to greater overall results and maintenance of gains. Some fluctuations of concentration levels are acceptable, and are also mostly unavoidable, but should be kept to a minimum.
This article covers the half-life's of the most commonly used steroids, esters and ancillary compounds.
Oral steroids
Drug
Active half-life
Anadrol / Anapolan50 (oxymetholone)
8 to 9 hours
Anavar (oxandrolone)
9 hours
Dianabol (methandrostenolone, methandienone)
4.5 to 6 hours
Methyltestosterone
4 days
Winstrol (stanozolol)
(tablets or depot taken orally)
9 hours
Steroid esters
The half-life applies to the ester regardless of hormone attached, for example trenbolone enanthate and primobolan (methenolone enanthate) will act very similarly to testosterone enanthate in terms of release rate.
Drug
Active half-life
Suspension
within 1 hour
Acetate
1 day
Propionate
1 day
Phenylpropionate
1-2 days
Butyrate
2-3 days
Valerate
3 days
Hexanoate
3 days
Caproate
4-5 days
Isocaproate
4-5 days
Heptanoate
5-6 days
Enanthate
5-6 days
Octanoate
6-7 days
Cypionate
6-7 days
Nonanoate
7 days
Decanoate
7-8 days
Undeclenate
8-9 days
Undecanoate
Approx 20 days
Ancillaries
Drug
Active half-life
Arimidex
3 days
Clenbuterol
1.5 days
Clomid
5 days
Cytadren
6 hours
Ephedrine
6 hours
T3
10 hours
A practical example is if one was to inject 100mg of testosterone propionate and allow blood levels to peak. In approx 36 hours time (half-life duration from the above tables) and providing no other injections had taken place, the level would be reduced to 50mg. Again, a further approx 36 hours down the line and levels would have dropped to 25mg, and the value keeps halving every approx 36 hours.
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If your still not convinced go read these two, since most of the above are based on and referances from below:
Schürmeyer, T. and Nieschlag, E. (1984), Comparative pharmacokinetics of testosterone enanthate and testosterone cyclohexanecarboxylate as assessed by serum and salivary testosterone levels in normal men. International Journal of Andrology, 7: 181–187. doi: 10.1111/j.1365-2605.1984.tb00775.x
Schulte-Beerbuhl M et al., Comparison of testosterone, dihydrotestosterone, luteinizing hormone, and follicle-stimulating hormone in serum after injection of testosterone enanthate or testosterone cypionate. Fertility and Sterility (1980) 33.2 : 201-203.