Super DMZ rx by heavyiron~updated November 2011

**heavyiron** · 08-13-2011, 04:32 PM

Super-DMZ rx by heavyiron

Super-DMZ rx, is an over the counter legal product that contains 10mg of Superdrol and 10mg of Dimethazine per capsule. Dimethazine is two steroid molecules bound together by a nitrogen atom. Upon ingestion, stomach acid separates the two steroid molecules that closely resemble methyldrostanolone (Superdrol) Therefore Super DMZ contains both Superdrol and Dimethazine. Dimethazine once broken down is similar to Superdrol though.

Dimethazine was a prescribed steroid at one time therefore we have human trials in which this steroid was used. This medication has been around since 1962 when it was presented in the literature. Early on it was sold under the Roxilon brand name. Dimethazine is basically an oral Masterone (drostanolone propionate). Published reports indicate that Dimethazine possesses an androgenic rating of 96 and an anabolic rating of 210. Furthermore it seems to possess little to no estrogenic or progestational activity. The reason I feel this is not identical to Superdrol is because Superdrol has a different androgenic/anabolic rating of 20/400 respectively. However Dimethazine is a strong steroid on its own. The addition of Superdrol makes Super DMZ rx an even stronger steroid.

Dimethazine is an oral c-17alpha alkylated steroid that is liver toxic to a degree. Note that in studies administering 20mg daily to female patients for 45-95 days, dimethazine was shown to induce modest to moderate bilirubinemia (excess bilirubin in the blood, indicative of hepatic stress) in close to 50% of patients. Approximately 25% of the patients noticed substantial increases in serum transaminases. These results suggest this steroid has significant hepatoxicity and should therefore be limited to shorter durations of use. Superdrol is also known for hepatoxicity so care must be taken when using Super DMZ rx.

Super DMZ is a potent oral steroid that should illicit solid gains in lean body mass with little water or fat gain depending on diet. Most users can tolerate between 20-40 mg (1-2 capsules) daily for 4-6 weeks however more adventuresome users may use up to 60mg (3 capsules) daily for shorter durations like 2-3 weeks. What struck me the most about this steroid is how rapid and dry my gains were. It reminded me of a faster acting, dryer Dianabol. However Super DMZ rx is much stronger mg for mg than Dianabol. Users of Super-DMZ can expect to add 8-12lbs of lean body mass in just 3-4 weeks. I personally had no noticable side effects from Super-DMZ at 2 capsules daily for 4 weeks. Super DMZ rx is a strong, clean steroid that can be used to increase lean mass, strength and power with little to no water retention in short periods of time.

Lipid and Organ Support

Because of the liver toxicity of Super DMZ rx I strongly recommend using liver supporting supplements such as ADVANCED CYCLE SUPPORT™ - Complete 'On Cycle' Prohormone Support and/or Liv 52 before and during administration of this designer steroid. Proper hydration is also recommended to lower stress on organs. Alcohol and other liver stressing medications like acetaminophen should be avoided during Super DMZ administration. Oral steroids often times negatively affect lipids therefore lipid supporting supplements should also be employed such as omega 3 fish oils, fiber and plant sterols. High blood pressure is another concern so that should be monitored regularly. Consult your health care professional before using any dietary supplements.

Post Cycle Therapy

Since Super DMZ rx will cause interruption of the Hypothalamic-Pituitary-Testicular Axis, post cycle therapy is strongly recommended. Bulbine natalensis or ProLensis™ is a amazing over the counter testosterone recovery supplement. It stimulates the production of GNRH and also increases cholesterol in the testes. Prolensis causes production of LH, which in turn signals the testis to produce testosterone. Evidence shows that ProLensis™ can stimulate LH 169% compared to study controls. Research further shows Testosterone is boosted a whopping 347%! This natural compound is a main ingredient in IronMagLabs Bodybuilding Supplements & Prohormones: Ultra Male Rx. Ultra male Rx also has pro sexual effects as well as boosting Testosterone. Some Testosterone boosting compounds may increase Estrogen but in rodent studies it was confirmed the the main ingredient in Ultra Male Rx actually decreases Estrogen by 35%. Ultra Male Rx is a legal way to significantly boost testosterone, control Estrogen and raise libido.

Sample Cycle

Weeks 1-4 Super DMZ RX-2 capsules per day
Weeks 1-8 Advanced Cycle Support-2 capsules per day (organ and lipid support)
Weeks 5-8 Ultra Male RX-1 capsule per day (post Cycle Therapy)

Super-DMZ rx is currently available for purchase without a prescription. Super-DMZ Rx™ Pro-Anabolic (Superdrol Dymethazine)

Chemical Name(s): Dimethazine
17beta-hydroxy 2alpha,17alpha-dimethyl 5alpha-androstan 3-one azine

Chemical Name(s): Superdrol
2a,17a-dimethyl-5a-androst-3-one-17b-ol
2a,17a-dimethyl-etiocholan-3-one-17b-ol

Referrences

1. Biological activity of dimethazine in the protein-anabolic field.
2. Protracted action of protein anabolism in gynecological oncology and its effect on hepatic function.
3. A new steroid with protein anabolic activity: dimethazine.
4. Biological determination of the secondary hormonal activities of dimethazine.
5. Antigonadotropic action of a new steroid with anabolizing activity studied in the anterior pituitary gland of the castrated rat
6. Methasteron-Associated Cholestatic Liver Injury: Clinicopathologic Findings in 5 Cases”
7. Anabolic and androgenic activities of Bulbine natalensis stem in male Wistar rats
8. Effect of aqueous extract of Bulbine natalensis (Baker) stem on the sexual behaviour of male rats.

**heavyiron** · 08-14-2011, 08:51 AM

Comparisons with methyltest, winny, anadrol and test prop showed better mytropic effect (muscle building) on the castrates with Dimethazine. In other words, mg for mg Dimethazine outperformed the above listed steroids for building muscle.

Biological activity of dimethazine in the protein-anabolic field.

Matscher, R.; Lupo, C.; De, P. Ruggieri. Lab. Ric. Ormonoter. Richter, Milan, Bollettino - Societa Italiana di Biologia Sperimentale (1962), 38 988-90. CODEN: BSIBAC ISSN: 0037-8771. Journal language unavailable. CAN 58:34623 AN 1963:34623 CAPLUS

Abstract

Dimethazine (I), 2,17-dimethyl-5-androstan-17-ol-3,3'-azine, was compared to methyltestosterone, oxymethalone, androstanazole and testosterone propionate in its protein-anabolic activity. The tests were made on castrated rats with a single hypodermic injection of 250 , on young male and female rats with increasing daily oral doses from 100 to 1000 for 30 days, and on adult male rats with daily oral doses of 1000 for 25 days. It was shown that I did not interfere with the growth of young animals; that adult rats treated with I gained, on an av., 20 g. more in wt. than the controls; and that I had a greater myotropic effect on castrates than the other steroids, and induced a higher N retention than methyltestosterone in adult males.

**heavyiron** · 08-14-2011, 08:52 AM

Here is an abstract where females took 20mg for 45+ days...and it appears that less than half had any liver issues.

Protracted action of protein anabolism in gynecological oncology and its effect on hepatic function.

Dambrosio, F.; Donatelli, G. Fontana. Univ. Milan, Cancro, Il (1963), 16(5), 553-604. Journal language unavailable. CAN 62:11656 AN 1965:11656 CAPLUS

Abstract

Twenty mg. of dimethazine, an anabolizing steroid, was administered daily for 45-95 days to 11 gynecological patients. More than 50% of the cases showed no change in the bilirubinemia, the others showed modest to moderate increases. The glutamic-oxalacetic and the glutamic-pyruvic transaminases of the serum increased greatly in 3 patients. The albumins concn. usually decreased in the course of the treatment, while the globulins concn. did not change.

**heavyiron** · 08-14-2011, 08:52 AM

This seems to support published reports that Dimethazine possesses a lower androgenic rating which would mean less androgenic sides and more anabolic muscle building effects.

A new steroid with protein anabolic activity: dimethazine.

De Ruggieri, P.; Matscher, R.; Gandolfi, C.; Chiaramonti, D.; Lupo, C.; Pietra, E.; Cavalli, R. Ormonoterap. Richter, Milan, Archivio di Scienze Biologiche (Bologna) (1963), 47(1), 1-19. CODEN: ASBIAL ISSN: 0004-0169. Journal language unavailable. CAN 60:46973 AN 1964:46973 CAPLUS

Abstract

Dimethazine (I) was evaluated for the following biol. activities: androgenic, N retaining, P retaining, and Ca retaining. The increase in uptake of -aminoisobutyric acid-1-14C and the increase in body wt. were also investigated. Data obtained, tabulated, and compared to those obtained with methyltestosterone established that I is a protein anabolic steroid with weak androgenic activity.

**heavyiron** · 08-14-2011, 08:52 AM

Little to no progestenic/estrogenic activity...

Biological determination of the secondary hormonal activities of dimethazine.

Lupo, C.; Matscher, R.; Ruggieri, P. De. Lab. Ric. Ormonoter. Richter, Milan., Bollettino - Societa Italiana di Biologia Sperimentale (1962), 38 990-4. CODEN: BSIBAC ISSN: 0037-8771. Journal language unavailable. CAN 58:34624 AN 1963:34624 CAPLUS

Abstract

Expts. with rats and rabbits showed that dimethazine, 2,17-dimethyl-5-androstan-17-ol-3,3'-azine has, in contrast to its protein-anabolic properties, practically no estrogenic, progestational, and corticoid activity. Similarly, it has no effect on liver glycogen, and no antiinflammatory action on the anaphylactoid edema.

**heavyiron** · 08-14-2011, 08:53 AM

Antigonadotropic action of a new steroid with anabolizing activity studied in the anterior pituitary gland of the castrated rat

Author Beghelli, V.; Mavrulis, A. Organization Univ. Bologna, Italy Publication Source Biochimica Applicata (1962), 9(No. 4), 179-88 Identifier-CODEN BIALAY ISSN 0006-298

Abstract:

Seventy-five female rats were divided into 5 groups; 15 served as controls; 60 were castrated and among these, 15 were treated with 17.alpha.-ethyl-19-nortestosterone (I), 15 with 17.alpha.-methyl-17.beta.-hydroxyandrosta-1,4-dien-3-one (II), and 15 with 2.alpha.,(Dimethazine) (III). With each of these steroids, treatment began 48 hrs. after the operation, with 1 mg. of the drug suspended in 0.5 ml. of saline (1% Tween 80 as suspending agent) once daily for 20 days by gavage. The last 15 received the vehicle only, according to the same schedule. The rats were sacrificed 24 hrs. after the last dose, and their pituitary glands and uteri examined. The castrates which received the vehicle only showed very pronounced gonadotropic pituitary hyperfunction, such as formation of castration cells and an increase in basophilic cells. Animals treated with I showed no castration cells at all, and only a small increase in basophilic cells. Those given II had some castration cells, and only a moderate redn. of basophilic cells compared with the untreated rats. The effect of III on the pituitary was almost negligible. In uterotropic activity, measured as the ratio of uterus wt. to body wt., I was most effective; III was intermediate; II showed almost no activity.

Conclusion:

This study showed little to no impact on the HPTA. This means that you will likely not experience the “shutdown” effect that is common to anabolics. This may make it easier to keep your gains in size and strength when your cycle is over.

**heavyiron** · 08-14-2011, 08:55 AM

Superdrol can cause hepatotoxicity so liver supporting supplements and proper hydration is strongly advised.

Clin Gastroenterol Hepatol. 2008 Feb;6(2):255-8. Epub 2008 Jan 9.

Methasteron-associated cholestatic liver injury: clinicopathologic findings in 5 cases.

Shah NL, Zacharias I, Khettry U, Afdhal N, Gordon FD.

Source
Department of Gastroenterology, Lahey Clinic Medical Center, Burlington, Massachusetts 01805, USA.

Abstract

BACKGROUND & AIMS:

Methasteron is a nutritional supplement used to increase weight or accelerate the build-up of muscle mass. The aim of this study was to describe 5 cases of hepatotoxicity in patients using methasteron seen at tertiary-care medical centers.

METHODS:
A case report design was used.

RESULTS:
Five previously healthy patients who used methasteron developed jaundice 2 weeks after discontinuation; they presented to a tertiary-care medical center 2 weeks later. Within another 2 to 3 weeks, bilirubin levels peaked. About 12 weeks after initial presentation, all cases resolved with no identifiable residual hepatic dysfunction.

CONCLUSIONS:
Methasteron use can result in severe hepatotoxicity. Liver failure can worsen after initial presentation, especially within 2 weeks. With close observation and supportive care, acute hepatic injury should resolve.

PMID:18187367 [PubMed - indexed for MEDLINE]

**heavyiron** · 08-14-2011, 08:56 AM

Old i-force article with some interesting claims about Dymethazine.

About Dymethazine:

In only 4 years since the Pro-Hormone ban of 2005 countless products have claimed to be as strong as or even stronger than the over the counter hormones once sold. After considerable time, energy, and research performed by i-Force's product formulation team, we are proud to announce the hormonal product everyone has been waiting for.

Featuring unheard of anabolic and myotropic effects, Dymethazine was compared to Methyltestosterone, Oxymethalone, Androstanazole and Testosterone Propionate in their protein-anabolic activity. Dymethazine was shown to have the HIGHEST myotropic (muscle building) effects out of any of the previously named steroids (Methyl-Test, Anadrol, Winstrol, and Testosterone Propionate)! In addition to this, it also displayed an ability to induce a higher rate of Nitrogen retention than Methyl-Test.(1)

In another study performed on Dymethazine, patients were administered Dymethazine for 45+ days. Liver values did not change for 50% of patients, while the other 50% noticed only modest to moderate increases in liver values(2). So, Dymethazine can increase liver values, however nowhere near the current methyl monsters on the market today. This means Dymethazine can be run for 4-6 weeks without the need of expensive liver support supplements.

Hormonal products that give huge strength/weight gains are usually associated with watery or wet gains due to large amounts of aromatization resulting in high levels of estrogen in the body. Too much estrogen can cause severe bloating, fat gain, and even potential growth problems. Dymethazine features 0% ability to aromatize and expresses an extremely weak androgenic activity (3). This means Dymethazine will produce intense gain, has very little to no liver impact, and will cause absolutely no estrogen related side effects.

Move beyond the pro-hormones of yesterday, and step into the future of Designer Steroids with Dymethazine. Consume 1-3 capsules, evenly spaced throughout the day. Do not use Dymethazine for longer than 6 weeks. Immediately begin PCT dosing protocol upon finishing Dymethazine. Wait at least 90 days before running Dymethazine again.

Referrences

1. Biological activity of dimethazine in the protein-anabolic field. Matscher, R.; Lupo, C.; De, P. Ruggieri. Lab. Ric. Ormonoter. Richter, Milan, Bollettino - Societa Italiana di Biologia Sperimentale (1962), 38 988-90. CODEN: BSIBAC ISSN: 0037-8771. Journal language unavailable. CAN 58:34623 AN 1963:34623 CAPLUS
2. Protracted action of protein anabolism in gynecological oncology and its effect on hepatic function. Dambrosio, F.; Donatelli, G. Fontana. Univ. Milan, Cancro, Il (1963), 16(5), 553-604. Journal language unavailable. CAN 62:11656 AN 1965:11656 CAPLUS
3. A new steroid with protein anabolic activity: dimethazine. De Ruggieri, P.; Matscher, R.; Gandolfi, C.; Chiaramonti, D.; Lupo, C.; Pietra, E.; Cavalli, R. Ormonoterap. Richter, Milan, Archivio di Scienze Biologiche (Bologna) (1963), 47(1), 1-19. CODEN: ASBIAL ISSN: 0004-0169. Journal language unavailable. CAN 60:46973 AN 1964:46973 CAPLUS

**cane87** · 08-15-2011, 02:02 AM

superdrol is some top notch shyt.. no denying that

**heavyiron** · 08-17-2011, 12:10 PM

Amazing performance for an OTC for sure.

**OrbitNutrition** · 08-17-2011, 06:39 PM

Love this product, great thread Heavy.

**Vibrant** · 08-17-2011, 08:46 PM

Great write up heavy. I got a few questions about super dmz. Does it need to be taken with test like all steroids do? Can it be used as a finisher in a cycle?

**heavyiron** · 08-17-2011, 09:52 PM

I prefer DMZ with Testosterone. It just makes the cycle more enjoyable. Definitely can be used to finish up a cycle.

**Vibrant** · 08-17-2011, 10:30 PM

Would you recommend doing super dmz for the last four weeks of my cycle?
My cycle is this, currently starting week 2:

1-10 test e 500mg may bump it to 750mg for weeks 11-16
1-16 eq 600mg
1-4 dbol kick start at 25mg ed

13-16 super dmz or maybe 15-18 so I can bridge the two weeks before pct???

Thanks for the help.

**OrbitNutrition** · 08-18-2011, 08:55 PM

Run it the last 4 weeks imo.

**heavyiron** · 11-24-2011, 07:11 PM

Originally Posted by OrbitNutrition

Run it the last 4 weeks imo.

Agreed

**Mkpaint** · 11-25-2011, 11:42 AM

Never ran anything what do you think a out 4weeks? Would I need pct since it doesn't cause shutdown?

**heavyiron** · 11-25-2011, 02:17 PM

PCT is needed. Dimethazine and Superdrol will cause shutdown.

You may use Ultra Male rx for PCT as it significantly increases Testosterone.

Weeks 1-4 Super DMZ RX-2 capsules per day
Weeks 1-8 Advanced Cycle Support-2 capsules per day (organ and lipid support)
Weeks 5-6 Ultra Male RX-1 capsule per day (post Cycle Therapy)

ULTRA MALE Rx™ Testosterone Enhancement Formula

Powered by ProLensis™

- Increases Testosterone Levels up to 347%
- Decreases Estrogen Levels up to 35%
- Increases Luteinizing Hormone Levels up to 169%
- Increases Libido, Stamina & Energy
- Scientifically Supported Extract

View label: (click to open)
ULTRA MALE Rx™ Testosterone Enhancement Formula

**heavyiron** · 11-25-2011, 03:15 PM

Main ingredient in Ultra Male Rx

Pharm Biol. 2010 May;48(5):568-76.

Anabolic and androgenic activities of Bulbine natalensis stem in male Wistar rats.

Yakubu MT, Afolayan AJ.

Source

Centre for Phytomedicine Research, Department of Botany, University of Fort Hare, Alice, South Africa.

Abstract

Aqueous extract of Bulbine natalensis Baker (Asphodelaceae) stem at 25, 50 and 100 mg/kg body weight was investigated for anabolic and androgenic effects in male Wistar rats. Sixty male rats were grouped into four (A-D) consisting of 15 each. Group A (control) was orally treated with 0.5 mL of distilled water for 14 days while groups B, C and D were treated like the control except they received 0.5 mL containing 25, 50, and 100 mg/kg body weight of the extract respectively. All the doses of the extract increased (P <0.05) the testicular-body weight ratio as well as alkaline phosphatase activity, glycogen, sialic acid, protein, and cholesterol content of the testes except the single administration of 100 mg/kg body weight which compared well (P>0.05) with the controls for glycogen and cholesterol. The testicular and serum testosterone concentration were increased except in the 100 mg/kg body weight where the effect on the tissue and serum hormone did not manifest until after the first and seven daily doses respectively. Testicular acid phosphatase activity, serum follicle stimulating and luteinizing hormone concentrations also increased at all the doses except in the 100 mg/kg body weight where the effect on the enzyme and the hormone did not manifest until after seven days. The increases were most pronounced in the 50 mg/kg body weight extract treated animals. The results indicate anabolic and androgenic activities of Bulbine natalensis stem in male rat testes with the 50 mg/kg body weight of the extract exhibiting the highest anabolizing and androgenic activities. These activities further support the folkloric use of the plant most especially at 50 mg/kg body weight in the management of male sexual dysfunction in South Africa.

PMID:20645801 [PubMed - indexed for MEDLINE]

**heavyiron** · 11-25-2011, 03:17 PM

Int J Androl. 2009 Dec;32(6):629-36. Epub 2008 Aug 15.

Effect of aqueous extract of Bulbine natalensis (Baker) stem on the sexual behaviour of male rats.

Yakubu MT, Afolayan AJ.

Source

Centre for Phytomedicine Research, Department of Botany, University of Fort Hare, Alice, South Africa.

Abstract

The phytochemical constituents of aqueous extract of Bulbine natalensis (Baker) stem and its effect on male rat sexual behaviour were evaluated for 7 days. Phytochemical screening revealed the presence of saponins, cardiac glycoside, tannins, alkaloids and anthraquinones. Administration of the extract at the doses of 25 and 50 mg/kg body weight resulted in the significant increase (p < 0.05) in mount frequency, intromission frequency, ejaculatory latency, ejaculation frequency, serum testosterone and luteinizing hormone concentrations, computed indices of sexual behaviour, erection, quick flips, long flips and total penile reflexes whereas the mount latency, intromission latency and post-ejaculatory interval were significantly decreased (p < 0.05) throughout the experimental period. The 100 mg/kg body weight of the extract produced contrasting pattern to the lower doses of the extract in all the parameters of sexual behaviour monitored throughout the experimental period. The results are indicative of prosexual stimulatory potentials of Bulbine natalensis in male rats. The aqueous extract of Bulbine natalensis stem at these doses (25 and 50 mg/kg body weight) may be used in the management of disorders of desire/libido, premature ejaculation and erectile dysfunction in males.

PMID:18710410 [PubMed - indexed for MEDLINE]

**heavyiron** · 12-01-2011, 10:20 AM

It's looking like the FDA/DEA may finally be banning Superdrol in January which means our current formulas using Superdrol (Super-DMZ Rx & Metha-Drol Extreme) will no longer be produced.

We have Super-DMZ Rx in stock right now and we have another shipment of both Super-DMZ Rx and Metha-Drol Extreme coming next week, however this may be our last batch of both products.

Bottom line, you may want to stock up on them while you can. If this ban does take effect we will be re-formulating both products with another compound which has yet to be finalized.

**SloppyJ** · 12-01-2011, 10:43 AM

Are you really pushing that Male RX over a real PCT?

**GMO** · 12-01-2011, 11:32 AM

^^^

**heavyiron** · 12-01-2011, 12:09 PM

Originally Posted by SloppyJ

Are you really pushing that Male RX over a real PCT?

There are several good abstracts on the main ingredient in Ultra Male rx boosting T levels over 300% that are posted in this thread brother. So yes, I advocate using Ultra Male rx for an OTC PCT. Also the LH increase from Ultra Male rx is well over 100%.

**Boomer182** · 12-01-2011, 04:33 PM

Day 1 of taking it. I did see some much needed grunt, I pushed it harder today, and surprisingly, I was able to see a big improvement in my lifts. I cant wait to see how this plays out.

**jaxx34** · 12-02-2011, 08:18 AM

Originally Posted by Boomer182

Day 1 of taking it. I did see some much needed grunt, I pushed it harder today, and surprisingly, I was able to see a big improvement in my lifts. I cant wait to see how this plays out.

Kool,mine just hit the mailbox today,keep us updated,I'm not gonna start mine till I stop working 15 hour days

and can spend some time in the gym!

**TJTJ** · 12-11-2011, 07:14 PM

As far as the Superdrol (2a,17a-dimethyl-5a-androst-3-one-17b-ol) goes What is the max daily dose? Not talking about with Dymethazine (17b-hydroxy-2a,17b-dimethyl-5a-androstan-3-one-azine) Just the Superdrol.

**heavyiron** · 12-11-2011, 08:23 PM

Originally Posted by TJTJ

As far as the Superdrol (2a,17a-dimethyl-5a-androst-3-one-17b-ol) goes What is the max daily dose? Not talking about with Dymethazine (17b-hydroxy-2a,17b-dimethyl-5a-androstan-3-one-azine) Just the Superdrol.

20-40mg daily is pretty common on SD.

**TJTJ** · 12-11-2011, 08:26 PM

Originally Posted by heavyiron

20-40mg daily is pretty common on SD.

Right on.

Thanks Heavy

**GMO** · 12-13-2011, 08:20 AM

I just started DMZ again yesterday and looking forward to the strength, vascularity and muscle density that comes with it's use.

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