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Halotestin? Whos used it?

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  1. #1
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    Halotestin? Whos used it?

    Anybody used halotestin? How were the strength/size gains? I cant find many reviews about it so I thought Id ask you guys.

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    from the stuff I've read it works extremely well when stacked with a test base.. it helps you push more for bigger gains and the test helps you solidify it.

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    I've used real Halotestin and it's awesome for aggression, instant strength increases, and hardening. Isn't really used for gains. Usually used on a cutting cycle, or by athletes before competition, a power lifters favorite. Highly toxic though and maybe a little addictive. I stopped buying them because I would stay on them too long.

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    Been several years ago, but Halo is great at getting that extra rep. You'll harden up, but not really put on any size.

    Still a fav!

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    Just read that it's great for a pre wo, ha ha

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    Used it back in day... I was younger then so might have been that but I was a major dick on it. Only shit I can remember being on that actually made my fucking crazy irrate. Was great for aggresion at the gym... Felt like a beast.. It hardened me up pretty good too. I liked the stuff alot just seemed a little hard on me.. After awhile on it I started feeling like shit.
    The comments, ideas & experiences expressed on this forum are based on purely fictional research done on gigantic lab rats

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    Yeah I guess its more liver toxic than A-bombs

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    Quote Originally Posted by Livebig14 View Post
    Yeah I guess its more liver toxic than A-bombs
    But not as bad as cheque drops :P ..also has a different purpose.. Most dont run it because it is used as an aggression drug.. But it also is supposed to really help with rbc and strength.. It's effects are non-ar mediated so stacking dbol isnt recommended.. But that is primarily due to hepatoxicity.. I cant find the stuff I was reading.. Mebe I can when I get to my pc..

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    havent run it, but from what i've heard its great for cutting, extra aggression and strength help to maintain size/strength while on lower calories, will harden you up and doesnt tend to give bloat, heard it helps with vascularity as well but not sure to what degree (i like EQ for that personally ) .. let us know how it goes if you run it, im a big fan of the hardening/lean gain AAS and have had my eye on halo for a while..

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    Eq boosts vascularity because it increases rbc.. Halo does this as well.. But better

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    Some HALO info (copy paste)

    Halotestin Tablets contain fluoxymesterone, an androgenic hormone.
    Fluoxymesterone is a white or nearly white, odorless, crystalline powder, melting at or about 240° C, with some decomposition. It is practically insoluble in water, sparingly soluble in alcohol, and slightly soluble in chloroform.
    The chemical name for fluoxymesterone is androst-4-en-3-one, 9-fluoro-11,17-dihydroxy-17-methyl-, (11β,17β)-. The molecular formula is C20H29FO3 and the molecular weight 336.45.
    The structural formula is represented below:

    Each Halotestin tablet, for oral administration, contains 2 mg, 5 mg or 10 mg fluoxymesterone. Inactive ingredients: calcium stearate, corn starch, FD&C Yellow No. 5, lactose, sorbic acid, sucrose, tragacanth. In addition, the 2 mg tablet contains FD&C Yellow No. 6 and the 5 mg and 10 mg contain FD&C Blue No. 2.
    Halotestin - Clinical Pharmacology

    Endogenous androgens are responsible for normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. These effects include growth and maturation of the prostate, seminal vesicles, penis, and scrotum; development of male hair distribution, such as beard, pubic, chest, and axillary hair; laryngeal enlargement, vocal cord thickening, and alterations in body musculature and fat distribution. Drugs in this class also cause retention of nitrogen, sodium, potassium, and phosphorus, and decreased urinary excretion of calcium. Androgens have been reported to increase protein anabolism and decrease protein catabolism. Nitrogen balance is improved only when there is sufficient intake of calories and protein.
    Androgens are responsible for the growth spurt of adolescence and for eventual termination of linear growth, brought about by fusion of the epiphyseal growth centers. In children, exogenous androgens accelerate linear growth rates, but may cause disproportionate advancement in bone maturation. Use over long periods may result in fusion of the epiphyseal growth centers and termination of the growth process. Androgens have been reported to stimulate production of red blood cells by enhancing production of erythropoietic stimulation factor.
    During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH). At large doses of exogenous androgens, spermatogenesis may also be suppressed through feedback inhibition of pituitary follicle stimulating hormone (FSH).
    Inactivation of testosterone occurs primarily in the liver.
    The half-life of fluoxymesterone after oral administration is approximately 9.2 hours.
    Indications and Usage for Halotestin

    In the male—Halotestin Tablets are indicated for

    1. Replacement therapy in conditions associated with symptoms of deficiency or absence of endogenous testosterone.
      1. Primary hypogonadism (congenital or acquired) testicular failure due to cryptorchidism, bilateral torsion, orchitis , vanishing testis syndrome; or orchidectomy.
      2. Hypogonadotropic hypogonadism (congenital or acquired)—idiopathic gonadotropin or LHRH deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation.

    2. Delayed puberty, provided it has been definitely established as such, and is not just a familial trait.

    In the female—Halotestin Tablets are indicated for palliation of androgen-responsive recurrent mammary cancer in women who are more than one year but less than five years postmenopausal, or who have been proven to have a hormone- dependent tumor as shown by previous beneficial response to castration.


    Contraindications


    1. Known hypersensitivity to the drug
    2. Males with carcinoma of the breast
    3. Males with known or suspected carcinoma of the prostate gland
    4. Women known or suspected to be pregnant
    5. Patients with serious cardiac, hepatic or renal disease

    Warnings

    Hypercalcemia may occur in immobilized patients and in patients with breast cancer. If this occurs, the drug should be discontinued.
    Prolonged use of high doses of androgens (principally the 17-α alkyl-androgens) has been associated with development of hepatic adenomas, hepatocellular carcinoma, and peliosis hepatis—all potentially life-threatening complications.
    Cholestatic hepatitis and jaundice may occur with 17-α-alkyl-androgens. Should this occur, the drug should be discontinued. This is reversible with discontinuation of the drug.
    Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking.
    Edema, with or without congestive heart failure, may be a serious complication in patients with pre-existing cardiac, renal or hepatic disease.
    Gynecomastia may develop and occasionally persists in patients being treated for hypogonadism.
    Androgen therapy should be used cautiously in males with delayed puberty. Androgens can accelerate bone maturation without producing compensatory gain in linear growth. The effect on bone maturation should be monitored by assessing bone age of the wrist and hand every six months.
    This drug has not been shown to be safe and effective for the enhancement of athletic performance. Because of the potential risk of serious adverse health effects, this drug should not be used for such purpose.
    Precautions

    General

    Women should be observed for signs of virilization which is usual following androgen use at high doses. Discontinuation of drug therapy at the time of evidence of mild virilism is necessary to prevent irreversible virilization. A decision may be made by the patient and the physician that some virilization will be tolerated during treatment for breast carcinoma.
    Patients with benign prostatic hypertrophy may develop acute urethral obstruction. Priapism or excessive sexual stimulation may develop. Oligospermia may occur after prolonged administration or excessive dosage. If any of these effects appear, the androgen should be stopped and if restarted, a lower dosage should be utilized.
    This product contains FD&C Yellow No. 5 (tartrazine) which may cause allergic-type reactions (including bronchial asthma) in certain susceptible individuals. Although the overall incidence of FD&C Yellow No. 5 (tartrazine) sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity.
    Information for patients

    Patients should be instructed to report any of the following: nausea, vomiting, changes in skin color, and ankle swelling. Males should be instructed to report too frequent or persistent erections of the penis and females any hoarseness, acne, changes in menstrual periods or increase in facial hair.
    Laboratory tests

    Women with disseminated breast carcinoma should have frequent determination of urine and serum calcium levels during the course of androgen therapy (See WARNINGS).
    Because of the hepatotoxicity associated with the use of 17-alpha-alkylated androgens, liver function tests should be obtained periodically.
    Periodic (every six months) X-ray examinations of bone age should be made during treatment of prepubertal males to determine the rate of bone maturation and the effects of androgen therapy on the epiphyseal centers.
    Hemoglobin and hematocrit levels (to detect polycythemia) should be checked periodically in patients receiving long-term androgen administration.
    Serum cholesterol may increase during androgen therapy.
    Drug interactions

    Androgens may increase sensitivity to oral anticoagulants. Dosage of the anticoagulant may require reduction in order to maintain satisfactory therapeutic hypoprothrombinemia.
    Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone.
    In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, insulin requirements.
    Drug/Laboratory test interferences

    Androgens may decrease levels of thyroxine-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.
    Carcinogenesis, mutagenesis, impairment Of Fertility

    Animal data: Testosterone has been tested by subcutaneous injection and implantation in mice and rats. The implant induced cervical-uterine tumors in mice, which metastasized in some cases. There is suggestive evidence that injection of testosterone into some strains of female mice increases their susceptibility to hepatoma. Testosterone is also known to increase the number of tumors and decrease the degree of differentiation of chemically-induced carcinomas of the liver in rats.
    Human data: There are rare reports of hepatocellular carcinoma in patients receiving long-term therapy with androgens in high doses. Withdrawal of the drugs did not lead to regression of the tumors in all cases.
    Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking.
    This compound has not been tested for mutagenic potential. However, as noted above, carcinogenic effects have been attributed to treatment with androgenic hormones. The potential carcinogenic effects likely occur through a hormonal mechanism rather than by a direct chemical interaction mechanism.
    Impairment of fertility was not tested directly in animal species. However, as noted below under Adverse Reactions, oligospermia in males and amenorrhea in females are potential adverse effects of treatment with Halotestin Tablets. Therefore, impairment of fertility is a possible outcome of treatment with Halotestin.
    Pregnancy

    Teratogenic effects Pregnancy Category X. (See CONTRAINDICATIONS.)
    Nursing mothers

    Halotestin is not recommended for use in nursing mothers.
    Pediatric use

    Androgen therapy should be used very cautiously in children and only by specialists aware of the adverse effects on bone maturation. Skeletal maturation must be monitored every six months by an X-ray of the hand and wrist (See WARNINGS).
    Adverse Reactions

    Endocrine and urogenital

    Female: the most common side effects of androgen therapy are amenorrhea and other menstrual irregularities; inhibition of gonadotropin secretion; and virilization, including deepening of the voice and clitoral enlargement. The latter usually is not reversible after androgens are discontinued. When administered to a pregnant woman, androgens can cause virilization of external genitalia of the female fetus.
    Male: Gynecomastia, and excessive frequency and duration of penile erections. Oligospermia may occur at high dosage.
    Skin and appendages

    Hirsutism, male pattern of baldness, seborrhea, and acne.
    Fluid and electrolyte disturbances

    Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.
    Gastrointestinal

    Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis (See WARNINGS).
    Hematologic

    Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.
    Nervous system

    Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.
    Allergic

    Hypersensitivity, including skin manifestations and anaphylactoid reactions.
    Drug Abuse and Dependence

    Controlled Substance Class

    Fluoxymesterone is a controlled substance under the Anabolic Steroids Control Act, and Halotestin Tablets has been assigned to Schedule III.
    Overdosage

    There have been no reports of acute overdosage with the androgens.
    Halotestin Dosage and Administration

    The dosage will vary depending upon the individual, the condition being treated, and its severity. The total daily oral dose may be administered singly or in divided (three or four) doses.
    Male hypogonadism

    For complete replacement in the hypogonadal male, a daily dose of 5 to 20 mg will suffice in the majority of patients. It is usually preferable to begin treatment with full therapeutic doses which are later adjusted to individual requirements. Priapism is indicative of excessive dosage and is indication fortemporary withdrawal of the drug.
    Delayed puberty

    Dosage should be carefully titrated utilizing a low dose, appropriate skeletal monitoring, and by limiting the duration of therapy to four to six months.
    Inoperable carcinoma of the breast in the female

    The recommended total daily dose for palliative therapy in advanced inoperable carcinoma of the breast is 10 to 40 mg. Because of its short action, fluoxymesterone should be administered to patients in divided, rather than single, daily doses to ensure more stable blood levels. In general, it appears necessary to continue therapy for at least one month for a satisfactory subjective response, and for two to three months for an objective response.
    How is Halotestin Supplied

    Halotestin Tablets, round and scored, are available in the following strengths and colors:
    2 mg (peach)
    Bottles of 100 NDC 0009-0014-01
    5 mg (light green)
    Bottles of 100 NDC 0009-0019-06
    10 mg (green)
    Bottles of 30 NDC 0009-0036-03
    Bottles of 100 NDC 0009-0036-04
    Store at controlled room temperature 20° to 25°C (68° to 77°F) [see USP].
    Rx only

    810 804 708
    692851
    May 2002

    Halotestin
    fluoxymesterone tablet Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0009-0014 Route of Administration ORAL DEA Schedule CIII INGREDIENTS Name (Active Moiety) Type Strength fluoxymesterone (fluoxymesterone) Active 2 MILLIGRAM In 1 TABLET calcium stearate Inactive corn starch Inactive FD&C Yellow No. 5 Inactive lactose Inactive sorbic acid Inactive sucrose Inactive tragacanth Inactive FD&C Yellow No. 6 Inactive Product Characteristics Color ORANGE (peach) Score 2 pieces Shape ROUND (ROUND) Size 7mm Flavor
    Imprint Code Halotestin;2 Contains Coating false Symbol false Packaging # NDC Package Description Multilevel Packaging 1 0009-0014-01 100 TABLET In 1 BOTTLE None
    Halotestin
    fluoxymesterone tablet Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0009-0019 Route of Administration ORAL DEA Schedule CIII INGREDIENTS Name (Active Moiety) Type Strength fluoxymesterone (fluoxymesterone) Active 5 MILLIGRAM In 1 TABLET calcium stearate Inactive corn starch Inactive FD&C Yellow No. 5 Inactive lactose Inactive sorbic acid Inactive sucrose Inactive tragacanth Inactive FD&C Blue No. 2 Inactive Product Characteristics Color GREEN (light green) Score 2 pieces Shape ROUND (ROUND) Size 7mm Flavor
    Imprint Code Halotestin;5 Contains Coating false Symbol false Packaging # NDC Package Description Multilevel Packaging 1 0009-0019-06 100 TABLET In 1 BOTTLE None
    Halotestin
    fluoxymesterone tablet Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0009-0036 Route of Administration ORAL DEA Schedule CIII INGREDIENTS Name (Active Moiety) Type Strength fluoxymesterone (fluoxymesterone) Active 10 MILLIGRAM In 1 TABLET calcium stearate Inactive corn starch Inactive FD&C Yellow No. 5 Inactive lactose Inactive sorbic acid Inactive sucrose Inactive tragacanth Inactive FD&C Blue No. 2 Inactive Product Characteristics Color GREEN (GREEN) Score 2 pieces Shape ROUND (ROUND) Size 7mm Flavor
    Imprint Code Halotestin;10 Contains Coating false Symbol false Packaging # NDC Package Description Multilevel Packaging 1 0009-0036-03 30 TABLET In 1 BOTTLE None 2 0009-0036-04 100 TABLET In 1 BOTTLE None
    Revised: 02/2006Pharmacia and Upjohn Company

    More Halotestin resources







    Compare Halotestin with other medications







    Related Halotestin Information



    Availability Prescription only
    CSA Schedule Moderate abuse potential

    Pregnancy Category Not for use in pregnancy
    Approval History FDA approved 1956



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    Drug Class

    Androgens and anabolic steroids
    Delayed Puberty, Male
    testosterone, Depo-Testosterone, Android, More...
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    The comments, ideas & experiences expressed on this forum are based on purely fictional research done on gigantic lab rats

  12. #12
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    Awesome stuff. Keeps your muscles full when you're dieting and feel like shit. Keeps your aggression high so you can still power through workouts even when you're calorie depleted. Makes you strong as fuck.

    That cyborg graininess that the pros have? Halotestin had a strong roll in that look.

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    I can only say who try one time BD Halotestex always order more.

  14. #14
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    Quote Originally Posted by Livebig14 View Post
    Anybody used halotestin? How were the strength/size gains? I cant find many reviews about it so I thought Id ask you guys.

    Don't look for size gains from it, but it definitely will give you increased strength. That and the muscle hardening effects are the two best effects of this compound IMO. I don't particularly like the aggression effect, as I am alpha as it is. That stuff can turn me into a real piece of work.

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    Quote Originally Posted by GMO View Post
    Don't look for size gains from it, but it definitely will give you increased strength. That and the muscle hardening effects are the two best effects of this compound IMO. I don't particularly like the aggression effect, as I am alpha as it is. That stuff can turn me into a real piece of work.
    ^ I agree. Makes me a bit pissy, much like Tren. It may well be the very best for strength, however.

  16. #16
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    thanks guys im looking for something that will give me size seems like halo is better used when cutting

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    Pretty much covered everything so far but something interesting I read about it. Apparently it's sometimes prescribed for guys with delayed puberty? Anyone know why? I just can't imagine what purpose it would serve or that docs would actually give people this shit?
    http://www.purchasepeptides.com/idev...ate.php?id=112
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    Quote Originally Posted by Digitalash View Post
    Pretty much covered everything so far but something interesting I read about it. Apparently it's sometimes prescribed for guys with delayed puberty? Anyone know why? I just can't imagine what purpose it would serve or that docs would actually give people this shit?
    lol not sure I would think for delayed puberty they would just prescribe test injections as its easier on the body and enhances the male sex characteristics.

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    Used it. Loved it. However, BE SURE to take it with test. Although it made me stronger, my erections were at half mast and I'd bust my nut in 5 seconds with a half chub woody. Not exactly the best way to impress the ladies. In the gym, I feel the raging vicious aggressiveness is second to none when it comes to Halo.

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    Iv used it.... Added in 50mg about 3hr before a squat session. Felt good so I maxed out and added 25+ lbs to my last max from 2wks before. I say 25+lbs cuz I went up 25 and it went up pretty easy but didn't want to go higher so i'm sayin 25+....

    Yes it was from WP..... The only good thing I got from them, so no I'm not a fan of WP, the the halo worked.
    Last edited by Usealittle; 08-31-2011 at 10:30 AM.

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    Quote Originally Posted by Livebig14 View Post
    thanks guys im looking for something that will give me size seems like halo is better used when cutting
    The first thing to start with is Test and the best Test for size is Suspension or TNE if you don't mind pinning ED. If you do then I prefer Enanthate. Next up is EQ to increase appetite and RBC. I think EQ is a better choice than Adrol for RBC because of less sides and Adrol can decrease appetite. Next is Dbol to for size and euphoria that you were looking for with Halotestin. Proviron is also great for freeing up all that test and as an antiestrogen for OCT. Depending on the length of the cycle you could do half Deca and half EQ.

  22. #22
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    Quote Originally Posted by OnPoint88 View Post
    The first thing to start with is Test and the best Test for size is Suspension or TNE if you don't mind pinning ED. If you do then I prefer Enanthate. Next up is EQ to increase appetite and RBC. I think EQ is a better choice than Adrol for RBC because of less sides and Adrol can decrease appetite. Next is Dbol to for size and euphoria that you were looking for with Halotestin. Proviron is also great for freeing up all that test and as an antiestrogen for OCT. Depending on the length of the cycle you could do half Deca and half EQ.
    Yeah thanks man. This is only my second cycle so I dont really want more than 2 compounds and maybe an oral kickstart

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    Quote Originally Posted by Livebig14 View Post
    Yeah thanks man. This is only my second cycle so I dont really want more than 2 compounds and maybe an oral kickstart
    Test Suspension or TNE is plenty kickstart then.

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    Halo so fukn expensive, not sure worth it

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    Real Halotestin is always expensive Ahrnold!

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    Quote Originally Posted by World-Pharma.org View Post
    Real Halotestin is always expensive Ahrnold!
    That is, unless you know someone who knocked off a US pharmacy many many years ago (15 yrs ago) and got real actual Halotestin round minty green tabs. They were either 5 or 10mg each. I'm thinking 5 b/c we took 4 about 2 hours before workouts and BAM!

    ** Note to LE - I wasn't present at the time of the pharmacy raid - Nor did I have any idea beforehand, nor did I associate with the friend of a friend of a friend of a friend who knew the person who did it - so go EFF youselves.

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    Quote Originally Posted by VonEric View Post
    Halotestin Tablets contain fluoxymesterone, an androgenic hormone.
    Fluoxymesterone is a white or nearly white, odorless, crystalline powder, melting at or about 240° C, with some decomposition. It is practically insoluble in water, sparingly soluble in alcohol, and slightly soluble in chloroform.
    The chemical name for fluoxymesterone is androst-4-en-3-one, 9-fluoro-11,17-dihydroxy-17-methyl-, (11β,17β)-. The molecular formula is C20H29FO3 and the molecular weight 336.45.
    The structural formula is represented below:

    Each Halotestin tablet, for oral administration, contains 2 mg, 5 mg or 10 mg fluoxymesterone. Inactive ingredients: calcium stearate, corn starch, FD&C Yellow No. 5, lactose, sorbic acid, sucrose, tragacanth. In addition, the 2 mg tablet contains FD&C Yellow No. 6 and the 5 mg and 10 mg contain FD&C Blue No. 2.
    Halotestin - Clinical Pharmacology

    Endogenous androgens are responsible for normal growth and development of the male sex organs and for maintenance of secondary sex characteristics. These effects include growth and maturation of the prostate, seminal vesicles, penis, and scrotum; development of male hair distribution, such as beard, pubic, chest, and axillary hair; laryngeal enlargement, vocal cord thickening, and alterations in body musculature and fat distribution. Drugs in this class also cause retention of nitrogen, sodium, potassium, and phosphorus, and decreased urinary excretion of calcium. Androgens have been reported to increase protein anabolism and decrease protein catabolism. Nitrogen balance is improved only when there is sufficient intake of calories and protein.
    Androgens are responsible for the growth spurt of adolescence and for eventual termination of linear growth, brought about by fusion of the epiphyseal growth centers. In children, exogenous androgens accelerate linear growth rates, but may cause disproportionate advancement in bone maturation. Use over long periods may result in fusion of the epiphyseal growth centers and termination of the growth process. Androgens have been reported to stimulate production of red blood cells by enhancing production of erythropoietic stimulation factor.
    During exogenous administration of androgens, endogenous testosterone release is inhibited through feedback inhibition of pituitary luteinizing hormone (LH). At large doses of exogenous androgens, spermatogenesis may also be suppressed through feedback inhibition of pituitary follicle stimulating hormone (FSH).
    Inactivation of testosterone occurs primarily in the liver.
    The half-life of fluoxymesterone after oral administration is approximately 9.2 hours.
    Indications and Usage for Halotestin

    In the male—Halotestin Tablets are indicated for

    1. Replacement therapy in conditions associated with symptoms of deficiency or absence of endogenous testosterone.
      1. Primary hypogonadism (congenital or acquired) testicular failure due to cryptorchidism, bilateral torsion, orchitis , vanishing testis syndrome; or orchidectomy.
      2. Hypogonadotropic hypogonadism (congenital or acquired)—idiopathic gonadotropin or LHRH deficiency, or pituitary-hypothalamic injury from tumors, trauma, or radiation.
    2. Delayed puberty, provided it has been definitely established as such, and is not just a familial trait.
    In the female—Halotestin Tablets are indicated for palliation of androgen-responsive recurrent mammary cancer in women who are more than one year but less than five years postmenopausal, or who have been proven to have a hormone- dependent tumor as shown by previous beneficial response to castration.


    Contraindications


    1. Known hypersensitivity to the drug
    2. Males with carcinoma of the breast
    3. Males with known or suspected carcinoma of the prostate gland
    4. Women known or suspected to be pregnant
    5. Patients with serious cardiac, hepatic or renal disease
    Warnings

    Hypercalcemia may occur in immobilized patients and in patients with breast cancer. If this occurs, the drug should be discontinued.
    Prolonged use of high doses of androgens (principally the 17-α alkyl-androgens) has been associated with development of hepatic adenomas, hepatocellular carcinoma, and peliosis hepatis—all potentially life-threatening complications.
    Cholestatic hepatitis and jaundice may occur with 17-α-alkyl-androgens. Should this occur, the drug should be discontinued. This is reversible with discontinuation of the drug.
    Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking.
    Edema, with or without congestive heart failure, may be a serious complication in patients with pre-existing cardiac, renal or hepatic disease.
    Gynecomastia may develop and occasionally persists in patients being treated for hypogonadism.
    Androgen therapy should be used cautiously in males with delayed puberty. Androgens can accelerate bone maturation without producing compensatory gain in linear growth. The effect on bone maturation should be monitored by assessing bone age of the wrist and hand every six months.
    This drug has not been shown to be safe and effective for the enhancement of athletic performance. Because of the potential risk of serious adverse health effects, this drug should not be used for such purpose.
    Precautions

    General

    Women should be observed for signs of virilization which is usual following androgen use at high doses. Discontinuation of drug therapy at the time of evidence of mild virilism is necessary to prevent irreversible virilization. A decision may be made by the patient and the physician that some virilization will be tolerated during treatment for breast carcinoma.
    Patients with benign prostatic hypertrophy may develop acute urethral obstruction. Priapism or excessive sexual stimulation may develop. Oligospermia may occur after prolonged administration or excessive dosage. If any of these effects appear, the androgen should be stopped and if restarted, a lower dosage should be utilized.
    This product contains FD&C Yellow No. 5 (tartrazine) which may cause allergic-type reactions (including bronchial asthma) in certain susceptible individuals. Although the overall incidence of FD&C Yellow No. 5 (tartrazine) sensitivity in the general population is low, it is frequently seen in patients who also have aspirin hypersensitivity.
    Information for patients

    Patients should be instructed to report any of the following: nausea, vomiting, changes in skin color, and ankle swelling. Males should be instructed to report too frequent or persistent erections of the penis and females any hoarseness, acne, changes in menstrual periods or increase in facial hair.
    Laboratory tests

    Women with disseminated breast carcinoma should have frequent determination of urine and serum calcium levels during the course of androgen therapy (See WARNINGS).
    Because of the hepatotoxicity associated with the use of 17-alpha-alkylated androgens, liver function tests should be obtained periodically.
    Periodic (every six months) X-ray examinations of bone age should be made during treatment of prepubertal males to determine the rate of bone maturation and the effects of androgen therapy on the epiphyseal centers.
    Hemoglobin and hematocrit levels (to detect polycythemia) should be checked periodically in patients receiving long-term androgen administration.
    Serum cholesterol may increase during androgen therapy.
    Drug interactions

    Androgens may increase sensitivity to oral anticoagulants. Dosage of the anticoagulant may require reduction in order to maintain satisfactory therapeutic hypoprothrombinemia.
    Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone.
    In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, insulin requirements.
    Drug/Laboratory test interferences

    Androgens may decrease levels of thyroxine-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.
    Carcinogenesis, mutagenesis, impairment Of Fertility

    Animal data: Testosterone has been tested by subcutaneous injection and implantation in mice and rats. The implant induced cervical-uterine tumors in mice, which metastasized in some cases. There is suggestive evidence that injection of testosterone into some strains of female mice increases their susceptibility to hepatoma. Testosterone is also known to increase the number of tumors and decrease the degree of differentiation of chemically-induced carcinomas of the liver in rats.
    Human data: There are rare reports of hepatocellular carcinoma in patients receiving long-term therapy with androgens in high doses. Withdrawal of the drugs did not lead to regression of the tumors in all cases.
    Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking.
    This compound has not been tested for mutagenic potential. However, as noted above, carcinogenic effects have been attributed to treatment with androgenic hormones. The potential carcinogenic effects likely occur through a hormonal mechanism rather than by a direct chemical interaction mechanism.
    Impairment of fertility was not tested directly in animal species. However, as noted below under Adverse Reactions, oligospermia in males and amenorrhea in females are potential adverse effects of treatment with Halotestin Tablets. Therefore, impairment of fertility is a possible outcome of treatment with Halotestin.
    Pregnancy

    Teratogenic effects Pregnancy Category X. (See CONTRAINDICATIONS.)
    Nursing mothers

    Halotestin is not recommended for use in nursing mothers.
    Pediatric use

    Androgen therapy should be used very cautiously in children and only by specialists aware of the adverse effects on bone maturation. Skeletal maturation must be monitored every six months by an X-ray of the hand and wrist (See WARNINGS).
    Adverse Reactions

    Endocrine and urogenital

    Female: the most common side effects of androgen therapy are amenorrhea and other menstrual irregularities; inhibition of gonadotropin secretion; and virilization, including deepening of the voice and clitoral enlargement. The latter usually is not reversible after androgens are discontinued. When administered to a pregnant woman, androgens can cause virilization of external genitalia of the female fetus.
    Male: Gynecomastia, and excessive frequency and duration of penile erections. Oligospermia may occur at high dosage.
    Skin and appendages

    Hirsutism, male pattern of baldness, seborrhea, and acne.
    Fluid and electrolyte disturbances

    Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.
    Gastrointestinal

    Nausea, cholestatic jaundice, alterations in liver function tests, rarely hepatocellular neoplasms and peliosis hepatis (See WARNINGS).
    Hematologic

    Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.
    Nervous system

    Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.
    Allergic

    Hypersensitivity, including skin manifestations and anaphylactoid reactions.
    Drug Abuse and Dependence

    Controlled Substance Class

    Fluoxymesterone is a controlled substance under the Anabolic Steroids Control Act, and Halotestin Tablets has been assigned to Schedule III.
    Overdosage

    There have been no reports of acute overdosage with the androgens.
    Halotestin Dosage and Administration

    The dosage will vary depending upon the individual, the condition being treated, and its severity. The total daily oral dose may be administered singly or in divided (three or four) doses.
    Male hypogonadism

    For complete replacement in the hypogonadal male, a daily dose of 5 to 20 mg will suffice in the majority of patients. It is usually preferable to begin treatment with full therapeutic doses which are later adjusted to individual requirements. Priapism is indicative of excessive dosage and is indication fortemporary withdrawal of the drug.
    Delayed puberty

    Dosage should be carefully titrated utilizing a low dose, appropriate skeletal monitoring, and by limiting the duration of therapy to four to six months.
    Inoperable carcinoma of the breast in the female

    The recommended total daily dose for palliative therapy in advanced inoperable carcinoma of the breast is 10 to 40 mg. Because of its short action, fluoxymesterone should be administered to patients in divided, rather than single, daily doses to ensure more stable blood levels. In general, it appears necessary to continue therapy for at least one month for a satisfactory subjective response, and for two to three months for an objective response.
    How is Halotestin Supplied

    Halotestin Tablets, round and scored, are available in the following strengths and colors:
    2 mg (peach)
    Bottles of 100 NDC 0009-0014-01
    5 mg (light green)
    Bottles of 100 NDC 0009-0019-06
    10 mg (green)
    Bottles of 30 NDC 0009-0036-03
    Bottles of 100 NDC 0009-0036-04
    Store at controlled room temperature 20° to 25°C (68° to 77°F) [see USP].
    Rx only

    810 804 708
    692851
    May 2002

    Halotestin
    fluoxymesterone tablet Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0009-0014 Route of Administration ORAL DEA Schedule CIII INGREDIENTS Name (Active Moiety) Type Strength fluoxymesterone (fluoxymesterone) Active 2 MILLIGRAM In 1 TABLET calcium stearate Inactive corn starch Inactive FD&C Yellow No. 5 Inactive lactose Inactive sorbic acid Inactive sucrose Inactive tragacanth Inactive FD&C Yellow No. 6 Inactive Product Characteristics Color ORANGE (peach) Score 2 pieces Shape ROUND (ROUND) Size 7mm Flavor
    Imprint Code Halotestin;2 Contains Coating false Symbol false Packaging # NDC Package Description Multilevel Packaging 1 0009-0014-01 100 TABLET In 1 BOTTLE None
    Halotestin
    fluoxymesterone tablet Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0009-0019 Route of Administration ORAL DEA Schedule CIII INGREDIENTS Name (Active Moiety) Type Strength fluoxymesterone (fluoxymesterone) Active 5 MILLIGRAM In 1 TABLET calcium stearate Inactive corn starch Inactive FD&C Yellow No. 5 Inactive lactose Inactive sorbic acid Inactive sucrose Inactive tragacanth Inactive FD&C Blue No. 2 Inactive Product Characteristics Color GREEN (light green) Score 2 pieces Shape ROUND (ROUND) Size 7mm Flavor
    Imprint Code Halotestin;5 Contains Coating false Symbol false Packaging # NDC Package Description Multilevel Packaging 1 0009-0019-06 100 TABLET In 1 BOTTLE None
    Halotestin
    fluoxymesterone tablet Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0009-0036 Route of Administration ORAL DEA Schedule CIII INGREDIENTS Name (Active Moiety) Type Strength fluoxymesterone (fluoxymesterone) Active 10 MILLIGRAM In 1 TABLET calcium stearate Inactive corn starch Inactive FD&C Yellow No. 5 Inactive lactose Inactive sorbic acid Inactive sucrose Inactive tragacanth Inactive FD&C Blue No. 2 Inactive Product Characteristics Color GREEN (GREEN) Score 2 pieces Shape ROUND (ROUND) Size 7mm Flavor
    Imprint Code Halotestin;10 Contains Coating false Symbol false Packaging # NDC Package Description Multilevel Packaging 1 0009-0036-03 30 TABLET In 1 BOTTLE None 2 0009-0036-04 100 TABLET In 1 BOTTLE None
    Revised: 02/2006Pharmacia and Upjohn Company

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    Related Halotestin Information



    Availability Prescription only
    CSA Schedule Moderate abuse potential

    Pregnancy Category Not for use in pregnancy
    Approval History FDA approved 1956



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    Drug Class

    Androgens and anabolic steroids
    Delayed Puberty, Male
    testosterone, Depo-Testosterone, Android, More...
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