Thread: Going on 125mg a week or 175mg a week for TRT

125mg is the lowest I would go. In studies that dose yeilded about 570ng/dl total T.

Testosterone dose-response relationships in healthy young men

I cruise at 200 mg/week split into two 100 mg injections, puts me at about 900 ng/dl on the day of the injection. I feel awesome at that level!

Originally Posted by heavyiron

125mg is the lowest I would go. In studies that dose yeilded about 570ng/dl total T.

Testosterone dose-response relationships in healthy young men

Interesting. good post.

Yeah if you have a choice I'd go with 175 or more. Estro shouldn't be a problem at that level, cruising at 250mg I don't even seem to need an AI. I started with one and worked the dose down til I stopped taking it and haven't noticed any issues, will probably go get blood work soon just to be sure.

Originally Posted by deadlifter405

I cruise at 200 mg/week split into two 100 mg injections, puts me at about 900 ng/dl on the day of the injection. I feel awesome at that level!

I've started splitting my injections as well, about to invest in some slin pins just to make it a bit easier

Originally Posted by heavyiron

125mg is the lowest I would go. In studies that dose yeilded about 570ng/dl total T.

Testosterone dose-response relationships in healthy young men

Am I reading this wrong or does igf-1 drop on 125mg test, even though that's enough to raise free/total test?

IGF-I (ng/ml) (overall ANOVA P = 0.0001) 25 mg268 ± 26261 ± 35−7 ± 190.746250 mg246 ± 14225 ± 12−20 ± 100.0797125 mg299 ± 24282 ± 31−18 ± 170.3284300 mg314 ± 24388 ± 3074 ± 280.0272600 mg227 ± 20304 ± 2177 ± 130.0001

edit: It looked alot cleaner when I pasted it... here's the line I'm talking about though

125 mg-299 ± 24282 ± 31(igf-1=) −18 ± 17 0.3284

In that study it does look like IGF-1 did drop when it was administered at 125mg per wk...

Good reference post heavy!

Originally Posted by Digitalash

Am I reading this wrong or does igf-1 drop on 125mg test, even though that's enough to raise free/total test?

IGF-I (ng/ml) (overall ANOVA P = 0.0001) 25 mg268 ± 26261 ± 35−7 ± 190.746250 mg246 ± 14225 ± 12−20 ± 100.0797125 mg299 ± 24282 ± 31−18 ± 170.3284300 mg314 ± 24388 ± 3074 ± 280.0272600 mg227 ± 20304 ± 2177 ± 130.0001

edit: It looked alot cleaner when I pasted it... here's the line I'm talking about though

125 mg-299 ± 24282 ± 31(igf-1=) −18 ± 17 0.3284

It lowered just a tad but not significantly.

50 mg 566 ± 78 306 ± 58 −260 ± 64 0.0037

Look at what 50mgs of test did, its lower than the baseline. Is that due to shutdown?

Yes, that's due to shutdown since 50 mg/week is lesser than what a healthy man will produce naturally.

100 Mg/week is my prescribed dosage and I do feel fine at that level which is about 550 ng/dl but I feel much better when I supplement my dosage up to 200 mg/week. It's not high enough where I feel I need to use an AI as my libido is raging and my aggression is noticeably higher too. If I went much higher I'd probably want to add in 0.25 mg of Adex every 3rd day or so. No hcg since I'm an old fart who's done having kids and I use the 29ga slin pins too, makes it a lot easier.

Yeah that's lower than normal test levels, so igf-1 production will decrease. Which is why I was curious about the 125mg dosage, the 300mg and 600mg groups both had increased levels of igf which makes sense because they both increased free/total test. The 125mg group however still had elevated free/total but (slightly) decreased igf.