Thread: What you need to know regarding HGH and your thyroid

Here's what you need to know:

Don't run T3 with HGH. You want Synthroid 100-200mcg/d (T4). Or, you can use Armor thyroid which is 75mcgT4/18mcgT3. For some complex reason that is not completely understood, GH needs T4 around to be optimally effective. T4 deiodination to T3 occurs in all tissues as needed. But T3 will not go to T4. If you are healthy and on HGH, you will convert all the T3 you need. However, if you take Cytomel, you will suppress your endogenous T4 production - and your HGH therapy will be sub-optimally effective. There is no sense in wasting expensive HGH, right?

Start your T4 empericaly at 100-150 mcg per day. Take on an empty stomach before breakfast. Do not eat for 1 hour after taking T4. You do not taper T4 or T3. Your starting dose is just an educated guess based on your training load and body weight. You must check TSH, T4, and T3 labs 4-6 weeks after you start and adjust accordingly.


HGH feeds back onto the hypothalamus and causes the release of somatostatin. Somatostatin inhibits several pituitary peptides including gh of course, but also TSH. So thyroid support is necessary when on hgh therapy, especially when on higher doses. Hypothyroidism is the primary cause of the lethargy one gets while on hgh treatment.

In order for your liver and peripheral somatic organs (muscle, mitochondria) to respond optimally to HGH therapy, hypothyroidism should be treated. Now I'm not suggesting that supra-physiological thyroid levels are better, however, your not getting all the benefit from your HGH if you are hypothyroid.

Originally Posted by pieguy

Thyroid Hormone + Growth Hormone by Anthony Roberts with James Daemon, Ph.D.

Found the reasoning behind this idea. Good read for people with the time.

Nice article. I can attest that Yzfrr knows his shit on hgh. He has helped numerous times. I'm currently taking armour thyroid with my hgh. armour has 37 mcg of T4, and 9 mcg of T3. I take 2 every morning.