Thread: HCG Dosing --- atrophy resolution

Many people go 500iu e3d if 500iu bi-weekly isn't cutting it. Some AAS are more suppressive than others such as nandrolones and trenbolones so more might be needed.

Originally Posted by pieguy

Many people go 500iu e3d if 500iu bi-weekly isn't cutting it. Some AAS are more suppressive than others such as nandrolones and trenbolones so more might be needed.

^^^ This, what AAS are you using and how many mgs

Originally Posted by pieguy

Many people go 500iu e3d if 500iu bi-weekly isn't cutting it. Some AAS are more suppressive than others such as nandrolones and trenbolones so more might be needed.

Originally Posted by Dath

^^^ This, what AAS are you using and how many mgs

This and that^^^

Originally Posted by Dath

^^^ This, what AAS are you using and how many mgs

400 tren hex
300 test cyp
400 EQ

P.S. I already made up my mind and I am going to 500iu's MWF. Took my 2nd pin for the wk on W and already see an improvement.

That's a pretty low dose of EQ. You know it takes EQ quite a while to kick in right?

Originally Posted by pieguy

That's a pretty low dose of EQ. You know it takes EQ quite a while to kick in right?

I know it is a little low, but with the other compounds it seems to be working just fine right now. I am running the above for 10 wks (8 wks in) and then at the end of 10 wks I will drop the tren and up my test and EQ for the next 10 wks like this 500 test cyp, 600 EQ. I may even throw in some winny if I feel the need.

P.S. i know I dont think the EQ really kicken in until about wk 6.

Originally Posted by spartan1

P.S. I already made up my mind and I am going to 500iu's MWF. Took my 2nd pin for the wk on W and already see an improvement.

^^^^
Well there you go then.

I was doing 2x @ 500iu and it didnt help much.
Have since went to 500iu MWF and its definitely working better.

I have read many people saying that the best way if you need more is to take a smaller dose more times per week.

Me personally I run 250iu ED.

Look up "swale's protocol" and you'll see what a real hrt doctor has to say about it.

Originally Posted by rc771

I have read many people saying that the best way if you need more is to take a smaller dose more times per week.

Me personally I run 250iu ED.

Look up "swale's protocol" and you'll see what a real hrt doctor has to say about it.

Will do thanks.

Currently running 250iu ed. Started 5 days into my cycle, shrunk quite a bit though. :/

That's a lot of hardware to go through and ED just does not work with my schedule. So at this point 500 MWF seems to have them back to normal and I will keep it there through the end of my cycle.

Do any of you take time off from the HCG while on cycle? I was under the impression you could only take it for around 3 weeks at a time and then you had to take 3-4 weeks off, and then repeat that process for the duration of your cycle until 5 days before PCT starts.

Hey my experiance w/ eq is that i go on longer at lower dose cause it stacks excellent with test, i just started 300 eq 300 deca and 200 cyp, ill stay on that till summer, i got dbols for a jump start, but ill stay on longer and continue to gain cause thats how eq works, trust me, you can always up on your blends later and bam youll continue to grow, thats my experiance anyway, europe anabolic has 300 boldenone for 50 bucks thats cheap, good luck,
I ALSO UPPED MY HCG I BUY THE 5000 IU NOW AND GET THREE SHOTS A WEEK OUT OF EVERY VIAL. THATS AROUND 1600 A SHOT, IT WORKS GREAT.

i dont run the hcg constantly i go a week on one off a week on 2 weeks off, im lazy the less shots the better, but you can make any cycle the way you want with that, its versatile

3 HCG injects weekly is fine. You can also pulse it for 3-4 weeks and take some time off if you want but running it a whole 12 week cycle is fine.

Keep in mind fertility patients take WAY more HCG under a doctors supervision so damage to Leydig cells is likely overstated. Also there is some science that shows ED dosing of HCG is less effective in raising T levels.

This study on rats shows a refractory period of 60-96 hours after HCG administration. This may lend support to every 3-4 day injects of HCG rather than every day or every other day.



Testicular steroidogenesis after human chorionic gonadotropin desensitization in rats.

Chasalow F, Marr H, Haour F, Saez JM.

When a single injection of 500 I.U. of human chorionic gonadotropin (hCG) is given to rats there is an initial acute rise of plasma testosterone and of testicular content for both cyclic AMP and testosterone. This response correlates with an increase in both lyase and 17 alpha-hydroxylase activities. Thereafter both plasma and testicular testosterone decline and do not increase after a second injection of hCG. During this period of desensitization, isolated Leydig cells were insensitive to the steroidogenic stimulatory effect of both hCG and dibutyryl cyclic AMP. The post-cyclic AMP block is not due to an alteration of the cyclic AMP-dependent protein kinase but it is correlated with a decrease in both lyase and 17 alpha-hydroxylase activities of the Leydig cell's microsomes. This decrease is not caused by the absence of the recently described cytosol activator of this enzyme because its addition did not restore the enzymatic activity. Within 60 to 96 h after hCG injection there was a spontaneous increase of both plasma and testicular testosterone and this parallels the recovery of lyase and 17 alpha-hydroxylase activities. These results suggest that both enzymatic activities are regulated, directly or indirectly, by hCG, and that this is partly responsible for the hCG-induced steroidogenic refractoriness of Leydig cells.

PMID: 221476 [PubMed - indexed for MEDLINE]

Would you think one 500iu inj. a week would be better than splitting it up twice a week for trt?

Originally Posted by bigmoe65

Would you think one 500iu inj. a week would be better than splitting it up twice a week for trt?

500iu HCG twice weekly is ideal to restore ITT levels. However some guys need larger doses to elicit a response. I would not be opposed to 1,000iu HCG twice weekly as long as an AI was being used alongside the HCG.

Originally Posted by heavyiron

500iu HCG twice weekly is ideal to restore ITT levels. However some guys need larger doses to elicit a response. I would not be opposed to 1,000iu HCG twice weekly as long as an AI was being used alongside the HCG.

Im only using 150mgs of test so a 1000iu's is probably overkill for me. I will experiment when I get my hcg.

Originally Posted by bigmoe65

Im only using 150mgs of test so a 1000iu's is probably overkill for me. I will experiment when I get my hcg.

For HRT 500iu HCG twice weekly and a low dose AI is indicated.

Originally Posted by heavyiron

For HRT 500iu HCG twice weekly and a low dose AI is indicated.

Thats what I will do once the nuts get rolling again. Then Im gonna drop it to 500iu and see if I experience any shrinkage. I will be using formestane as my ai.