Is it true that the ER (estrogen receptor) is somehow different in different tissues? I was reading that tamoxifen (Nolvadex) was very effective at binding to the ER in breast tissue, but not effective at blocking estrogen in the hypothalmus or pituitary and therefore does not restore LH. The article then said Clomid kind of picks up there and increases LH production, it didn't say HOW, but I would assume clomid increases LH by blockin estrogen therefore signaling a drop ion sex hormones which signals a production of LH.
If that's how clomid works, why wouldn't nolvadex do the same thimg?
Do I need to add clomid to my PCT?
"I don't like small cars or real big women, but somehow I always find myself in 'em" - KR
I always feel worse doing a clomid only PCT, terrible. I also lose more strength than any other time using clomid. Sometimes paper and real life dont cross over, but perhaps there is a better explanation out there.
Some people mix both, I will be doing that next time because I have some clomid to kill. I just wont be using much.