Reply With Quotecan't this be avoided by tapering off?
Thyroid rebound
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Thread: Thyroid rebound
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09-17-2005, 09:31 PM #1Super Moderator SUPER MODERATOR
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Thyroid rebound
People keep asking about this one.
N Engl J Med 1975 Oct 2;293(14):681-4
Recovery of pituitary thyrotropic function after withdrawal of prolonged thyroid-suppression therapy.
Vagenakis AG, Braverman LE, Azizi F, Portinay GI, Ingbar SH.
The pattern of thyrotropin secretion was analyzed in seven euthyroid women, before and after withdrawal of long-term thyroid hormone, by serial measurements of thyroid 131l uptake, serum thyroxine, tri-iodothyronine, and thyrotropin concentrations, and the response to thyrotropin-releasing hormone. During exogenous hormone administration, 131l uptake was suppressed, and serum thyrotropin concentrations before and after administration of thyrotropin-releasing hormone were undetectable.
After withdrawal of exogenous hormone, thyrotropin secretory function was transiently impaired, as indicated by undetectable basal thyrotropin concentrations together with absence of response to thyrotropin-releasing hormone, and subsequently by normal values of basal thyrotropin concentration and normal responses to releasing hormone while serum thyroxine and tri-iodothyronine concentrations were subnormal.
Decreased thyrotropin reserve persisted for two to five weeks. Detectable values of serum thyrotropin (less than 1.2 muU per milliliter) and a normal 131l uptake usually occurred concurrently in two to three weeks. Serum thyroxine concentration returned to normal at least four weeks after hormone withdrawal.Motivation Bench form Charles Poliquin When I let go of what I am, I become what I might be. Lao-Tzu
Disclaimer: All health, fitness, diet, nutrition, anabolic steroid & supplement information posted here is intended for educational and informational purposes only, and is not intended as a substitute for proper medical advice from a medical doctor. We do not condone the use of anabolic steroids (AAS), all information about AAS is for educational and entertainment purposes only. If you choose to use AAS it's your responsibility to know the laws of the country that you live in. Consult your physician or health care professional before performing any of the exercises, or following any diet, nutrition or supplement advice described on this website.
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09-18-2005, 03:47 AM #2Registered User
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09-18-2005, 01:05 PM #3Super Moderator SUPER MODERATOR
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Even a small amount causes suppression, but my whole point was whats the big deal with a couple weeks when you've been on for YEARS? People seem to think that hardcore shutdown is going to be a problem, I never had any rebound at all although I wasn't on for years, only 6 weeks.
Motivation Bench form Charles Poliquin When I let go of what I am, I become what I might be. Lao-Tzu
Disclaimer: All health, fitness, diet, nutrition, anabolic steroid & supplement information posted here is intended for educational and informational purposes only, and is not intended as a substitute for proper medical advice from a medical doctor. We do not condone the use of anabolic steroids (AAS), all information about AAS is for educational and entertainment purposes only. If you choose to use AAS it's your responsibility to know the laws of the country that you live in. Consult your physician or health care professional before performing any of the exercises, or following any diet, nutrition or supplement advice described on this website.
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09-23-2005, 04:49 PM #4Aus BB
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I heard that it has a bigger shutdown effect on woman. Not sure how true that is.
Aus BB
Aus Bodybuilding Forum, Home of Australian Bodybuilding
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