Urgent; issue with injecting

franco9112 · 06-28-2006, 05:21 PM

I injected 750mg of Test E mid way up on my left quad (outer left side)yesterday. Everything seemed to go perfectly fine, no blood, no pain at the time of injection, etc. When I woke up this morning, my quad was extremely sore from mid way up to below my knee. The knee itself looks like a balloon. I have never experienced anything like this following a test injection. I made a doctors appointment for tomorrow because I'm almost unable to walk at this point but I'm wondering if any of you guys might know what's going on with here?

Let me know if there is more information needed to answer such a question. Thanks.

**dg806** · 06-28-2006, 08:01 PM

Thats a lot of volume for 1 shot. It should be sore. Usually it is broken down into 250mg 2-3 times a week (depending on dosage)

19-chief · 06-28-2006, 08:08 PM

my first response is to ask about the source... UGL, animal, or human grade?

franco9112 · 06-28-2006, 08:22 PM

Human Grade. I didn't consider that 750mg was perhaps too much for one shot and I'm certainly paying for it now.

SJ69 · 06-28-2006, 08:37 PM

try that w/ prop.

TJ Cline · 06-28-2006, 09:03 PM

I did 3cc's in my quads for years and it never gave me any problems....3cc's for quads or glutes is fine. Sounds like you have some bad stuff or possibly an infection.

lnvanry · 06-28-2006, 10:38 PM

Quote:

Originally Posted by ForemanRules

I did 3cc's in my quads for years and it never gave me any problems....3cc's for quads or glutes is fine. Sounds like you have some bad stuff or possibly an infection.

shouldn't 750mgs be 4.5cc?

TJ Cline · 06-28-2006, 11:31 PM

Quote:

Originally Posted by lnvanry

shouldn't 750mgs be 4.5cc?

250x3=750
Many Tests come in 250mg per cc/ml

**Mudge** · 06-29-2006, 01:56 AM

Quote:

Originally Posted by lnvanry

shouldn't 750mgs be 4.5cc?

That would make it 166mg/ml, an oddball number. Upjohn cypionate is 200mg/ml, otherwise most stuff is 250 or higher.

I have shot 3cc damn near anywhere a needle has gone in my body, I dont like quad shots, but that aside 3cc of volume has never bothered me anywhere I have shot gear. This is not high volume to me unless you have very small bodyparts, like a very small bicep and you were doing frequent shots.

Some people do 5cc in larger muscles, I am not suggesting just pointing this out.

franco9112 · 06-29-2006, 05:32 AM

The test is 250mg/ml and as I said, the last injection was 750mg or 3ml. It's not as inflamed today and walking is a bit easier so I think I'll skip the doctors appointment and hope for the best.

ag-guys · 06-29-2006, 06:34 AM

Quote:

Originally Posted by ForemanRules

I did 3cc's in my quads for years and it never gave me any problems....3cc's for quads or glutes is fine. Sounds like you have some bad stuff or possibly an infection.

Had some pain when did quad shots with over 1cc.

AG-Guys
www.AG-Guys.com

franco9112 · 06-29-2006, 08:00 AM

For future reference; do you guys think I should stick to glute shots with high doses of test or break it downt to twice a week injections and continue rotating sites? I certainly won't be able to hit spots like the calf with a high does if it causes my quad so much pain. Thanks for the remarks.

**dg806** · 06-29-2006, 08:31 AM

More than likely it was the solvent in it.

Trouble · 06-29-2006, 09:55 AM

Height, weight, natural somatype (body type), years of training. How well do your legs respond to training? Have you injected in this area frequently? How long has this test series been going on?

See, here's my thinking:

As was astutely pointed out, if the muscle mass isn't considerable, it just might be that your dose is sufficiently large to saturate not only the androgen receptors, but also nuclear receptors that hit up the immune response.

You swamped the wrong receptor with signal and you got your ping all right, right down in the knee where you artial circulation moved that slug of steroid, and aggravated the connective tissue in that joint.

If this is the case, dividing the dose into smaller volume injections, within the same muscle, isn't going to solve the problem.

Perhaps a little creative problem solving is warranted.

What do we add at the same time, to keep these other receptors from being hit so hard? Something transderma, applied well before injections are made. A combination of locally acting agents that hit up these inflammation response/immune regulating local receptors and forestall this unfortunate side effect.

Or, you might just try dropping the dose down; thats the most expedient and straightforward means of solving this problem.

While the immediate effect of test is local, its carried by peripheral circulation throughout the body. But at first, its present at high enough concentrations to cause this unwanted secondary receptor activation. And this is the cause of the effect. DG, it could be the solvent, but I rather think its the test concentration thats the culprit.

I will take up this issue, think through it, and get back to you.

largepkg · 06-29-2006, 10:44 AM

Quote:

Originally Posted by Trouble

Height, weight, natural somatype (body type), years of training. How well do your legs respond to training? Have you injected in this area frequently? How long has this test series been going on?

See, here's my thinking:

As was astutely pointed out, if the muscle mass isn't considerable, it just might be that your dose is sufficiently large to saturate not only the androgen receptors, but also nuclear receptors that hit up the immune response.

You swamped the wrong receptor with signal and you got your ping all right, right down in the knee where you artial circulation moved that slug of steroid, and aggravated the connective tissue in that joint.

If this is the case, dividing the dose into smaller volume injections, within the same muscle, isn't going to solve the problem.

Perhaps a little creative problem solving is warranted.

What do we add at the same time, to keep these other receptors from being hit so hard? Something transderma, applied maybe an hour or two before injectionl. A combination of locally acting agents that hit up these inflammation response/immune regulating local receptors and forestall this unfortunate side effect.

Or, you might just try dropping the dose down; thats the most expedient and straightforward means of solving this problem.

While the immediate effect of test is local, its carried by peripheral circulation throughout the body. But at first, its present at high enough concentrations to cause this unwanted secondary receptor activation. And this is the cause of the effect. DG, it could be the solvent, but I rather think its the test concentration thats the culprit.

I will take up this issue, think through it, and get back to you.

You make me think. I like people whom make me think.

franco9112 · 06-29-2006, 11:56 AM

I am 5'5'', 182lbs, and have been training naturally for six years. (The epitome of a mesomorph) I'm currently 4 weeks into a 10-week cycle of test E; it's only my second cycle and both have consisted of test E as the only AAS. I have injected into the left quad but only twice before and the last time was during my last cycle, roughly 12 months ago. I read the sticky here on spot injections among other literature so I feel as if the location wasn’t an issue. I have never had a problem gaining substantial mass in my lower body and presently I have moderately large quads. I have not measured recently but an indication of this is the fact that my waist is 29'' however I have to buy a 32'' pant to fit my butt/quads. Anyway, it’s feeling a little better but I’m still not walking correctly.

I really appreciate all of the remarks, you guys are quite helpful.

Trouble · 06-29-2006, 02:31 PM

Ach aye, I suspected as much. You haven't nearly the quad mass of some forum members here. Your last dose probably did overwhelm the wrong receptors, causing the exaggerated local inflammation response.

Lesson: skip the larger dose, try a smaller one, 'ere you repeat this debacle.

For rerefencence, you might consider the aftereffects of this type of induced damage.

You're going to slough off a percentage of the affected tissue, due to initiation of cell lysis to clean up the cell damage. It should be diffuse, in other words, spread out over the affected area, but may be more concentrated near or at the injection site.

There is the outside chance of an local infection as a cause of this site inflammation. I would be remiss if I didn't mention it as well.

IF it is an infection, and the source is a contaminated vial, where you to use it again at another site, you might have a similar painful repeat of this episode. Look for a faint cloudiness in the test vial, if you still have it; it might be a clue.

lnvanry · 06-29-2006, 03:44 PM

Quote:

Originally Posted by Mudge

That would make it 166mg/ml, an oddball number. Upjohn cypionate is 200mg/ml, otherwise most stuff is 250 or higher.

I have shot 3cc damn near anywhere a needle has gone in my body, I dont like quad shots, but that aside 3cc of volume has never bothered me anywhere I have shot gear. This is not high volume to me unless you have very small bodyparts, like a very small bicep and you were doing frequent shots.

Some people do 5cc in larger muscles, I am not suggesting just pointing this out.

I was think testE 200...thats what I always had...thats all I've ever seen

TJ Cline · 06-29-2006, 03:48 PM

Quote:

Originally Posted by franco9112

For future reference; do you guys think I should stick to glute shots with high doses of test or break it downt to twice a week injections and continue rotating sites? I certainly won't be able to hit spots like the calf with a high does if it causes my quad so much pain. Thanks for the remarks.

2x a week is much better than just one big shot once a week....you can do 2cc's on say Monday and 1cc on Friday.

**dg806** · 06-29-2006, 06:25 PM

Quote:

Originally Posted by Trouble

Lesson: skip the larger dose, try a smaller one, 'ere you repeat this debacle.

I hear an echo!

ag-guys · 06-30-2006, 05:25 AM

Quote:

Originally Posted by dg806

More than likely it was the solvent in it.

very true point

AG-Guys
www.AG-Guys.com

franco9112 · 06-30-2006, 02:18 PM

It's been three days and I no longer walk with a limp so it seems as if everything's alright. Thanks for the educational lessons everyone posted.

NOZZLEHEAD · 06-30-2006, 10:39 PM

Quote:

Originally Posted by Trouble

Look for a faint cloudiness in the test vial, if you still have it; it might be a clue.

A clue of what? Contamination in the vial?

franco9112 · 06-30-2006, 10:48 PM

...not sure what it's a sign of; I certainly don't feel qualified enough to conclude the matter.

Trouble · 07-01-2006, 09:22 AM

Either compound precipitation (that would result in the injection of unsolvated test and cause localized inflammation) or microbial contamination.

Given the frequency of similar reports of difficulty with quad injections, I would the case of overwhelming the local nuclear receptor and initiating cell inflammation, triggering excess pain, swelling, and cell death, is more likely to be the case.

luke69duke69 · 07-01-2006, 04:49 PM

I don't think you have an infection. Just too much gear in one spot. I had the exact same reaction to 3cc's in my quad, right down to the swollen knee.

06-28-2006, 05:21 PM	#1
franco9112 Registered User Join Date: Mar 2006 Posts: 17	Urgent; issue with injecting I injected 750mg of Test E mid way up on my left quad (outer left side)yesterday. Everything seemed to go perfectly fine, no blood, no pain at the time of injection, etc. When I woke up this morning, my quad was extremely sore from mid way up to below my knee. The knee itself looks like a balloon. I have never experienced anything like this following a test injection. I made a doctors appointment for tomorrow because I'm almost unable to walk at this point but I'm wondering if any of you guys might know what's going on with here? Let me know if there is more information needed to answer such a question. Thanks.
franco9112 Registered User Join Date: Mar 2006 Posts: 17

06-28-2006, 08:01 PM	#2
dg806 Guardian of The Homeland Super Moderator Join Date: Jan 2002 Location: Charlotte NC Posts: 17,516	Thats a lot of volume for 1 shot. It should be sore. Usually it is broken down into 250mg 2-3 times a week (depending on dosage)
	www.sbmuscle.com

06-28-2006, 08:08 PM	#3
19-chief Registered User Join Date: Jan 2004 Location: south eastern us Posts: 854 Photos: 4	my first response is to ask about the source... UGL, animal, or human grade?
	Information that the character 19-chief presents is totally fictitious in nature and is presented for role playing purposes only. The opinions presented do not encourage the use of illegal substances nor take the place of professional medical advice.

06-28-2006, 08:22 PM	#4
franco9112 Registered User Join Date: Mar 2006 Posts: 17	Human Grade. I didn't consider that 750mg was perhaps too much for one shot and I'm certainly paying for it now.
franco9112 Registered User Join Date: Mar 2006 Posts: 17

06-28-2006, 08:37 PM	#5
SJ69 Registered User Join Date: Nov 2003 Location: Philly Posts: 1,031 Photos: 1	try that w/ prop.
	"I don't like small cars or real big women, but somehow I always find myself in 'em" - KR

06-28-2006, 09:03 PM	#6
TJ Cline Member Join Date: May 2005 Posts: 12,544	I did 3cc's in my quads for years and it never gave me any problems....3cc's for quads or glutes is fine. Sounds like you have some bad stuff or possibly an infection.
TJ Cline Member Join Date: May 2005 Posts: 12,544

06-29-2006, 05:32 AM	#10
franco9112 Registered User Join Date: Mar 2006 Posts: 17	The test is 250mg/ml and as I said, the last injection was 750mg or 3ml. It's not as inflamed today and walking is a bit easier so I think I'll skip the doctors appointment and hope for the best.
franco9112 Registered User Join Date: Mar 2006 Posts: 17

06-29-2006, 08:00 AM	#12
franco9112 Registered User Join Date: Mar 2006 Posts: 17	For future reference; do you guys think I should stick to glute shots with high doses of test or break it downt to twice a week injections and continue rotating sites? I certainly won't be able to hit spots like the calf with a high does if it causes my quad so much pain. Thanks for the remarks.
franco9112 Registered User Join Date: Mar 2006 Posts: 17

06-29-2006, 08:31 AM	#13
dg806 Guardian of The Homeland Super Moderator Join Date: Jan 2002 Location: Charlotte NC Posts: 17,516	More than likely it was the solvent in it.
	www.sbmuscle.com

06-29-2006, 09:55 AM	#14
Trouble Anti-mediocrity Elite Member Join Date: Mar 2006 Location: On Loan From A Distant Star System Posts: 2,076 Photos: 2	I'm curious, a few questions Height, weight, natural somatype (body type), years of training. How well do your legs respond to training? Have you injected in this area frequently? How long has this test series been going on? See, here's my thinking: As was astutely pointed out, if the muscle mass isn't considerable, it just might be that your dose is sufficiently large to saturate not only the androgen receptors, but also nuclear receptors that hit up the immune response. You swamped the wrong receptor with signal and you got your ping all right, right down in the knee where you artial circulation moved that slug of steroid, and aggravated the connective tissue in that joint. If this is the case, dividing the dose into smaller volume injections, within the same muscle, isn't going to solve the problem. Perhaps a little creative problem solving is warranted. What do we add at the same time, to keep these other receptors from being hit so hard? Something transderma, applied well before injections are made. A combination of locally acting agents that hit up these inflammation response/immune regulating local receptors and forestall this unfortunate side effect. Or, you might just try dropping the dose down; thats the most expedient and straightforward means of solving this problem. While the immediate effect of test is local, its carried by peripheral circulation throughout the body. But at first, its present at high enough concentrations to cause this unwanted secondary receptor activation. And this is the cause of the effect. DG, it could be the solvent, but I rather think its the test concentration thats the culprit. I will take up this issue, think through it, and get back to you. Last edited by Trouble : 06-29-2006 at 11:10 AM.

06-29-2006, 11:56 AM	#16
franco9112 Registered User Join Date: Mar 2006 Posts: 17	I am 5'5'', 182lbs, and have been training naturally for six years. (The epitome of a mesomorph) I'm currently 4 weeks into a 10-week cycle of test E; it's only my second cycle and both have consisted of test E as the only AAS. I have injected into the left quad but only twice before and the last time was during my last cycle, roughly 12 months ago. I read the sticky here on spot injections among other literature so I feel as if the location wasn’t an issue. I have never had a problem gaining substantial mass in my lower body and presently I have moderately large quads. I have not measured recently but an indication of this is the fact that my waist is 29'' however I have to buy a 32'' pant to fit my butt/quads. Anyway, it’s feeling a little better but I’m still not walking correctly. I really appreciate all of the remarks, you guys are quite helpful.
franco9112 Registered User Join Date: Mar 2006 Posts: 17

06-29-2006, 02:31 PM	#17
Trouble Anti-mediocrity Elite Member Join Date: Mar 2006 Location: On Loan From A Distant Star System Posts: 2,076 Photos: 2	Ach aye, I suspected as much. You haven't nearly the quad mass of some forum members here. Your last dose probably did overwhelm the wrong receptors, causing the exaggerated local inflammation response. Lesson: skip the larger dose, try a smaller one, 'ere you repeat this debacle. For rerefencence, you might consider the aftereffects of this type of induced damage. You're going to slough off a percentage of the affected tissue, due to initiation of cell lysis to clean up the cell damage. It should be diffuse, in other words, spread out over the affected area, but may be more concentrated near or at the injection site. There is the outside chance of an local infection as a cause of this site inflammation. I would be remiss if I didn't mention it as well. IF it is an infection, and the source is a contaminated vial, where you to use it again at another site, you might have a similar painful repeat of this episode. Look for a faint cloudiness in the test vial, if you still have it; it might be a clue.

06-30-2006, 02:18 PM	#22
franco9112 Registered User Join Date: Mar 2006 Posts: 17	It's been three days and I no longer walk with a limp so it seems as if everything's alright. Thanks for the educational lessons everyone posted.
franco9112 Registered User Join Date: Mar 2006 Posts: 17

06-30-2006, 10:48 PM	#24
franco9112 Registered User Join Date: Mar 2006 Posts: 17	...not sure what it's a sign of; I certainly don't feel qualified enough to conclude the matter.
franco9112 Registered User Join Date: Mar 2006 Posts: 17

07-01-2006, 09:22 AM	#25
Trouble Anti-mediocrity Elite Member Join Date: Mar 2006 Location: On Loan From A Distant Star System Posts: 2,076 Photos: 2	Either compound precipitation (that would result in the injection of unsolvated test and cause localized inflammation) or microbial contamination. Given the frequency of similar reports of difficulty with quad injections, I would the case of overwhelming the local nuclear receptor and initiating cell inflammation, triggering excess pain, swelling, and cell death, is more likely to be the case.

07-01-2006, 04:49 PM	#26
luke69duke69 Registered User Join Date: Aug 2004 Posts: 478	I don't think you have an infection. Just too much gear in one spot. I had the exact same reaction to 3cc's in my quad, right down to the swollen knee.
	"I may not be the best looking guy in the bar, but I'm the only one talking to you" - J King

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