View Full Version : Equipoise~boldenone undecylenate

12-27-2010, 12:44 PM

(boldenone undecylenate)

By Anthony Roberts

Equipoise was actually created while attempting to make a product which would be be a long acting injectable d-bol (Methandrostenolone). What was actually created was a product which, in the real world acts nothing like D-bol, despite it´s similarity to it chemically. A simple way to think of Equipoise, chemically at least, is simply as Dianabol without the 17-alpha-methyl group (that´s the thing which makes D-bol able to be ingested orally and not be destroyed by your liver). However, having had first hand experience with both Equipoise as well as D-bol, I can tell you that the results from each are vastly different.

To make Equipoise, a double bond was added between carbon atoms 1 and 2 of the Steran Nucleus of Testosterone. What does this mean? Well, first of all, since Equipoise was created by one simple modification in the testosterone molecule, you could rightly suspect that it shares many similarities with it. Equipoise is just as anabolic as testosterone (as you can tell by its anabolic rating above), but only half as androgenic. Those ratings can be quite deceiving though, as I don´t know anyone who would claim that you can gain as much weight on Equipoise as you can gain on an equal amount of testosterone (even though strength gains from the two compounds are very similar).

It´s not very common to compare Equipoise to testosterone; however a far more common comparison is between Equipoise and Deca. I suspect this is because when Dan Duchaine introduced this compound to the steroid using community, he made an immediate comparison to Deca, speculating that it would act similarly to Deca but like a much stronger version of it. Equipoise doesn´t actually act much like deca at all; Deca is actually a progestin and a 19-nor derived steroid whereas Equipoise is more closely related to testosterone (being only one double bond differ rent). Duchaine later rescinded his original statement on Equipoise and said that it was disappointing as a mass builder when compared with deca, but a far better drug than for both strength gains and vascularity. Unfortunately, the myth that Equipoise´s action is similar to Deca´s has persisted for nearly 2 decades after he revised his opinion; this is most evident on internet message boards today, where many will advise against including both of them in a cycle because "they act the same way."

The 1-2 double bond that Equipoise has is responsible for many of its characteristics. First of all, it acts to slow aromatization (conversion into estrogen). The best estimate is that it does so at roughly half the rate of testosterone (1). This is the best number I´ve found in studies. Athletes almost never report estrogenic side effects with Equipoise, even when the dose is up to a gram per week. Side effects caused by estrogen include oily skin, acne, and gynocomastia, and as I said, those are usually not found from Equipoise. Virilization (development of male sexual characteristics in women) is almost never seen with this compound, when reasonable doses are used by female athletes. This is one of the few injectable compounds which could be successfully be used by female athletes and bodybuilders, and isn´t often faked.

Clinical Equipoise and Athletes

That double bond is also responsible for Equipoise´s resistance for being changed by the 5- 5-Alpha-reductase enzyme (2)(3). This enzyme converts a small amount of Boldenone into Dihydroboldenone, which is a very potent androgen (7x as anabolic as testosterone)(4). As I said though, such a small amount of it is converted that it´s really of no concern to most athletes taking Equipoise. This factor, plus its low aromatization rate mean athletes don´t need to consider using ancillaries with Equipoise.

Athletes taking Equipoise often report a slow and constant buildup of quality muscle, and certainly this has been my experience with the drug. I would speculate that this slow buildup of muscle is due to the very long ester attached to the Boldenone; Undeclynate is a longer ester than the decanoate ester by one carbon. Thus, we could expect the accumulation of muscle from Equipoise to actually occur at a slightly slower rate than that found with Deca (nandrolone decanoate). This leads me to advise that if you are considering the use of Equipoise, you should consider using it for no less than 12 weeks. Equipoise, like deca, is also detectable in your system for a long time (although it is substantially less than deca´s detection time).

Strangely, shorter estered versions of Boldenone are available as well. Anecdotally, many people (and manufacturers) claim that this produces less water retention...but water retention from Equipoise is virtually unheard of, so I consider this to be a silly idea.

An informal poll I took on Steroid.com (as well as with my friends) seems to put the ideal dose of Equipoise at 600mgs/week. Most people I asked about their Equipoise experience with Equipoise seemed to think that using over 600mgs/week produced no additional results, but the jump from 400mgs/week to 600mgs/week produced noticeable additional gains, and thus was warranted. I have personally found very nice results from 400mgs-600mgs/week myself.

Equipoise Side Effects

One of the most pronounced effects in Equipoise is its ability to raise your RBC´s (red blood cells). This is very typical of anabolic steroids; however, Equipoise would appear to do it to a slightly greater degree than most. One of the other effects most Equipoise users report is an increased appetite. I can say that this is true of me, also; this factor makes it impossible for me to diet on it. It´s because of this ability to increase appetite that many will include Equipoise in a mass cycle, and it´s for the quality of muscle gained on it that many will include it in a cutting cycle. It´s probably the most versatile injectable compound, next to testosterone. People even use a low dosed version of Equipoise to blend with irritating injectable drugs suck as testosterone suspension or Propionate. I´m thinking of the old Ganabol version which was dosed at 50mgs/ml, here... it´s not that Equipoise is especially good to cut other steroids with, but the low dose and cost of Ganabol made it ideal to do this with, when sterile oil wasn´t available or desirable. This low dosed version was also very popular with women, who were comfortable shooting 1cc of this stuff every few days or every week.

Equipoise will cause a suppression of your hormones, such as endogenous testosterone, so I would also recommend using injectable testosterone in any cycle containing it. Failure to do so could result in possible sexual dysfunction and other sides.

Buy Equipoise

Finally, when you buy equipoise, one of the best parts of Equipoise is it´s low price and high availability. Equipoise is produced by most Underground Labs at very reasonable prices. You shouldn´t be paying more than $50 for a 10cc bottle dosed at 200mgs/ml, and that price is true of Mexican veterinary products and underground labs alike.

I´d have to say that due to its incredible versatility, availability, and low price, Equipoise is going to be a staple in many cycles for a long time.

Equipoise Steroid Profile

Boldenone Undeclynate
(1,4-androstadiene-3-one,1 7b-ol)
Molecular Weight(base): 286.4132
Molecular Weight (ester): 186.2936
Formula (base): C19H26O2
Manufacturer: Various
Effective Dose (Men): 200-600mgs/week
Effective Dose (Women): 50-100mgs/week
Active life: 15 days
Detection Time: Up to 5 months
Anabolic/ Androgenic ratio: 100:50

Endocrinology 71 (1962) 920-25
Metabolism of boldenone in man: gas chromatographic/mass spectrometric identification of urinary excreted metabolites and determination of excretion rates. Biol Mass Spectrom. 1992 Jan;21(1):3-16.
Gas chromatographic/mass spectrometric analysis of boldenone urinary metabolites in man. Yao Xue Xue Bao. 1991;26(5):362-6. Chinese. Erratum in: Yao Hsueh Hsueh Pao 1991;26(9):687.
Counsel et al., "Anabolic Agents. Derivatives of 5alpha-Androst-1-ene", J. Org. Chem., 27 (1962), 248-251


12-27-2010, 03:07 PM
Women and Equipoise

*Note: * caveat about typical use and not medical recommendation*

Equipoise Overview
Equipoise is an injectible steroid that does not aromatize. Since it does not convert to estrogen, it is a nice cycle that does not promote water retention.

Typical Use
For an off-season bulker without water retention, or at the beginning of a contest prep, again without water retention. Anecdotally some people experience an increase in hunger with EQ, so it might fit well with a bulker phase. EQ also promotes connective tissue, which can be useful in protecting the joints and ligaments while a cycle is increasing your strength (i.e. the joints become the weak link).

Typical Cycle
Dosage: 50-150 mg per week
Duration: 6-10 weeks

Potential Sides
- acne
- oily skin
- hairloss
- sore throat / cracking or changing voice
- chin hair growth
- interrupted period - would return roughly first full month after the duration of the EQ detection time following the last injection

01-03-2011, 01:35 AM
Thank you, Sassy, for adding this. I am very interested in the connective tissue regenerative properties of this compound. Given that nandrolone does this also, albeit through a different mechanism, I'm curious if the two might work well together?

01-03-2011, 01:38 AM
Thank you, Sassy, for adding this. I am very interested in the connective tissue regenerative properties of this compound. Given that nandrolone does this also, albeit through a different mechanism, I'm curious if the two might work well together?

interesting ! although EQ does have roughly half the amount of estrogen as testosterone. it does aromatize, just not as much as test does, or so I have heard. Maybe someone else can clarify?

01-03-2011, 03:02 PM
Anabolic Pharmacology

By Seth Roberts


Pharmacology is the study of drugs and their effects. Anabolic pharmacology is the study of drugs that have a growth-promoting effect in muscle. This column will explore anabolic pharmacology by profiling a different anabolic drug and its effects each month. The focus of discussion this month will be the anabolic androgenic steroid, Equipoise.

Boldenone is a 1-dehydro derivative of testosterone that has been sold as a veterinary preparation under the name Equipoise, and is largely known by this name. The formation of a double-bond in the 1,2 position changes the shape of the molecule slightly. This also changes the potency and characteristics of the molecule. Boldenone has a lower affinity than testosterone for the androgen receptor, making it less potent on a milligram-for-milligram basis.1 This steroid can be converted to estrogen, but less so than testosterone. In addition, boldenone is metabolized to 1,4 dienedione, which is a potent aromatase inhibitor.

Boldenone is converted by 5-alpha reductase to 1-testosterone, a more potent steroid, as well as to the 5-beta isomer— which is thought to be an inactive metabolite.2,3 Binding to sex hormone-binding globulin (SHBG) is much lower with boldenone than with testosterone, meaning a larger free plasma concentration but a shorter half-life in plasma.4 There is little-to-no binding to progesterone or glucocorticoid receptors, and no real data on the interaction of boldenone with the different enzyme systems.1
The undecyclenate ester of boldenone was the ester marketed under the original trade name. In recent years, the free base and other esters have become available as underground preparations. On the street, Equipoise is erroneously considered to have the same activity as Deca and is often substituted for Deca in a stack. Dan Duchaine, if not the originator of this myth, at the very least propagated it in his book Underground Steroid Handbook II. If you look at the structure, you can see that boldenone is structurally identical to dianabol without the C-17 alkylation.

Most people experience much less side effects with boldenone, compared to methandrostenolone. This is because boldenone converts to estradiol, while methandrostenolone converts to methylestradiol. Methylestradiol is a much more potent and long-lasting estrogen than plain estradiol. Since there is no C-17 alkylation, there is no liver toxicity associated with boldenone. Boldenone is rumored to be very good at increasing red blood cell production. While all androgens stimulate erythropoiesis, there is no evidence in the scientific literature that boldenone is superior in producing this effect.5,6,7,8

Boldenone undecyclenate is generally injected every four or five days, but some people will inject every day while others will inject once per week. The longer half-life of the undecyclenate ester would dictate an injection frequency of every 10-14 days, but there has been a trend toward more frequent dosing by anabolic-androgenic steroid (AAS) users, even with drugs known to have long half-lives. Dosing is generally kept pretty low (300-500 milligrams per week), but the low binding affinity would argue for twice that dosage, taken with testosterone.

The anabolic-to-androgenic ratios are favorable for boldenone, but people do not consider boldenone a particularly potent steroid— possibly due to the low doses that are utilized. Also, boldenone does not cause much water retention— so many people assume it is not working if they do not put on 10 pounds in one week. Boldenone is said to cause an increase in vascularity, although there is no mechanism to explain why boldenone would do this more than any other AAS.

Seth Roberts is a former pharmaceutical research scientist with over 10 years of pharmacological research in the discovery and development of novel therapeutics. If you want to learn more about Anabolic Steroids, pick up Seth's new book Anabolic Pharmacology at Ergogens - UnderConstruction (http://www.Ergogens.com). [© Seth Roberts, 2009. All rights reserved. For informational purposes only, not to be considered as medical advice or an endorsement of the use of illegal substances.]


1. Ojasoo T, Delettre J, Mornon JP, Turpin-VanDycke C, Raynaud JP: Towards the mapping of the progesterone and androgen receptors. J Steroid Biochem, 27(1-3):255-69, 1987.
2. Schanzer W, Donike M: Metabolism of boldenone in man: gas chromatographic/mass spectrometric identification of urinary excreted metabolites and determination of excretion rates. Biol Mass Spectrom, Jan;21(1):3-16, 1992.
3. Schanzer W: Metabolism of anabolic androgenic steroids. Clin Chem, Jul;42(7):1001-20, 1996.
4. Saartok T, Dahlberg E, Gustafsson JA: Relative binding affinity of anabolic-androgenic steroids: comparison of the binding to the androgen receptors in skeletal muscle and in prostate, as well as to sex hormone-binding globulin. Endocrinology, Jun;114(6):2100-6, 1984.
5. Gorshein D, Murphy S, Gardner FH. Comparative study on the erythropoietic effects of androgens and their mode of action. J Appl Physiol, 35(3):276-8, 1973.
6. Paulo LG, Fink GD, Roh BL, Fisher JW. Effects of several androgens and steroid metabolites on erythropoietin production in the isolated perfused dog kidney. Blood, 43(1):39-47, 1974.
7. Sanchez-Medal L, Gomez-Leal A, Duarte L, Guadalupe Rico M. Anabolic androgenic steroids in the treatment of acquired aplastic anemia. Blood, 34(3):283-300, 1969.
8. Alexanian R. Erythropoietin and erythropoiesis in anemic man following androgens. Blood, 33(4):564-72, 1969.

01-05-2011, 04:02 PM
what are your thoughts on dosing regularity Heavy?

01-05-2011, 05:17 PM
what are your thoughts on dosing regularity Heavy?
I typically stack with Test Cypionate which I would inject twice weekly, so I would just shoot the heavy long esters with the testosterone.

2 times per week on EQ, or Deca for that matter but once weekly is fine.