View Full Version : Estrogen: positively correlated with size but not strength

02-26-2011, 11:33 AM
Estrogen: positively correlated with size but not strength
by Anthony ******s

A recent study examining 1489 older men determined that estrogen (total estradiol) is negatively correlated with strength and performance. They also found that it was positively correlated with muscle mass, and not surprisingly, both serum testosterone as well as total testosterone were positively correlated with muscle mass, performance, and strength. If you’re not looking to get big, but you’re concerned with getting stronger, an aromatase inhibitor or an anti-estrogen might be a good choice during your next cycle.

Eur J Endocrinol2011 Feb 23. [Epub ahead of print]

Testosterone but not estradiol level is positively related to muscle strength and physical performance independent of muscle mass – a cross-sectional study in 1489 older men.

Auyeung TW, Lee JS, Kwok TC, Leung J, Ohlsson C, Vandenput L, Leung PC, Woo J.

T Auyeung, The S H Ho Centre of Gerontology and Geriatrics, The Chinese University of Hong Kong, Hong Kong, China.


Objective: To examine the relationship among different measures of testosterone and estradiol, muscle mass, muscle strength and physical performance; and to test whether the association of sex hormone level with muscle strength and physical performance was independent of muscle mass. Design and methods: A cross-sectional survey on 1489 community-dwelling men older than 64 years of age. Serum levels of testosterone and estradiol were measured by mass spectrometry and sex hormone binding globulin levels were measured by immunoradioassay. Muscle mass was examined by dual-energy X-ray absorptiometry and physical performance was assessed by hand-grip strength, gait speed, step length and chair-stand test. Results: Appendicular skeletal mass (ASM) was positively associated with total testosterone (TT) (p<0.001), free testosterone (FT) (p<0.001), total estradiol (E2) (p<0.001) but not free E2 (p=0.102). After adjustment for age, SHBG and relative ASM, both TT and FT were significantly associated with grip strength, narrow-walk speed and the composite neuromuscular score. Higher total estradiol, but not free estradiol was associated with lower grip strength (p<0.05) after adjustment for age, FT, SHBG and relative ASM. Conclusions: Testosterone level was related to both muscle mass, strength and physical performance. Total estradiol level, though related to muscle mass positively, affected muscle strength adversely in older men.

source (http://www.anthony******s.info/2011/02/estrogen-positively-correlated-with-size-but-not-strength/)

02-26-2011, 04:36 PM
Finally, a solid study to reference and it doesn't have to be 'speculation' anymore :)


03-08-2011, 11:41 AM
Good study, use an aromatase inhibitor and keep T high =)

03-08-2011, 10:30 PM
Nice I don't feel as bad taking my aromasin now. LOL