Originally posted by CRASHMAN
all viagra does is restrict blood from flowing outa the penis once it is erect it really doesn't make you hornier or etc it just won't go down once you blow so you can go over and over again if you got the will power and it doesn't get too sore from all that blood
In men, It doesn't get you hornier, that's true. In women, by engorging the clitoris (finsihing phase III clinical trials) it does stimulate sexual excitement. Remember, the clitoris is just an invaginated corpora cavernosa, the tissue on which viagra works.
Also keep in mind, viagra was initially a cardiac drug used for chest pain in Europe, so it does have some vasodilatory effects and may drop your blood pressure.
Overall, it functions as a phosphodiesterase inhibitor and through a series of chain reactions, causes an increase in cGMP-dependent protein kinases which affect smooth muscle relaxation and inflow of blood to the corpora cavernosa and other peripheral vascular beds. As a result, the lacunar spaces expand and blood becomes entrapped secondary to compression of venules against the tunica albuginea (i.e., the corporal veno-occlusive mechanism). For sufficient tumescence and rigidity to occur, the tunica albuginea must be sufficiently stiff to compress the venules penetrating it and thus block venous outflow.
The only difference between viagra and cialis is the half life. Both are phosphodiesterase inhibitors, both are dangerous when taken with nitroglycerin, viagra has a 4-6 hour half life, cialis almost 36 hours. In addition, viagra is not absorbed if taken with food, especially high fat food. Thus, with cialis, you can wine and dine your date and take it with your linguini alfredo and have a 36 hour hard on!