Hi John and thanks for the reply. You know, I did a shot in my left glute this morning thinking that maybe that area would take the shot a little better. Again, didn't even feel it going in, but 4 hours later the same pain set in. Yeah, it's prob just my body getting used to it. the good news is, the quad pain is easing off a little bit, and the glute pain is taking my mind of the quad. LOL! Hey, I have a question about the dosage though, I did 250MG Test E on Friday, and another 250 this morning (Monday). I originally planned on doing 500 in same shot once per week, but never did Test E before so I wanted to see how I took to 250 first. This morning i was a little leary about going to 500 after the quad pain from the last injection. Knowing that I'm probably gonna get some pain after every shot for a while, do you think I should just say screw it, and do the 500 once per week? Or split it up and do say 250 on Monday, and the other 250 on Thursday? By the way, I'm also doing 25MG d-bol ED. Thanks for any input!