IGF1-Des: Why is it much better then IGF-1 and IGF-1LR3 and how does it work?
Well IGF-1 Des is a lot like your normal IGF1 molecule with the exception that IGF1 has a 70 amino acid chain and IGF-1 Des has only 67. This is not a bad thing, there are purposefully 3 amino acids cleaved off and that is why it has a very low affinity to binding proteins which is a good thing as it makes it about 10X more potent than your normal IGF-1 peptide chain would be in the body.
The half-life of this peptide is still very short, the same as with IGF-1. IGF-1 Des it is MUCH more biologically active, giving much greater results over IGF-1 regardless of the similar active life span per dosing.
This matters to us because IGF-1 play's a major role in cell growth and development of tissues throughout the body and mind of nearly all animals. This goes from muscle-building and tendon-building effects to even neurological building effects. Really just about any role of growth in tissue has IGF-1 connected to it somehow; it is truly an amazing peptide to study.
Here is a very interesting comment showing the promising direction IGF-1 Des is going in the medical field with regards to possible mental enhancement: "This characterization of the acute actions of des-IGF-1 at hippocampal excitatory synapses may provide insight into the mechanism by which long-term increases in plasma IGF-1 impart cognitive benefits in aged rats." So as you see this is not just a very promising peptide to research from a simple tissue building stand point, but also for research work about the brain/mind and possibly enhancing it in aged subjects.
So should you still use normal IGF-1 in your studies? If IGF-1 Des is an option to get, then NO!
IGF-1 Des is far superior to IGF1 and possibly even IGF1LR3 judging from current studies out there.
Hey any of you guys used this with TB500? I am thinking of getting both but don't want to piss any money away ;-) thanks
I haven't, but I have been doing A LOT of research on TB500 and there is A LOT of positive feedback coming in. I plan on using this some time soon. I would not think its a waste if ran how most others are right now. I am very interested in this compound because I was in a car accident years ago and have a lot of back issues, I hope that this peptide may help me with tissue repair and pain (I'm losing some fluid and tissue in my back I am told) If you do use it PLEASE log it on the forum, I am very interested in ALL feedback on this peptide. Maybe someone will chime in who has used it. but from my research id say it is NOT a waste of money. I see alot of peeps running it somewhat like so: 2-3mg ew for a few weeks then 1-2 mg ew after that for couple more months. (just for ref, thought it may help you or others) Hope that helps somehow. :-)
Thanks allot man!
I am thinking of maybe trying the TB and igf1lr3 or des but have the igf for maybe the first 6 weeks of tb?
If you don't mind me asking how would you (if you where to) run the igf with TB500?
I know you just said you haven't used the TB yet, but you seem to have very good knowledge of this stuff so any suggestion I would greatly appreciate. :-)