Thread: Cialis: Do yourself a favor and read this.

Tadalafil citrate (Cialis) is in a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors and to understand the actions of CIA you must first understand what a "PDE5" is and what the inhibitor's actions are.

PDE5 Inhibitors are drugs used to block the degrading action of PDE5 on cyclic GMP in the smooth muscle cells and blood vessels. A main action found in the use of PDE5 inhibitors are its effects in the lining of the blood vessels supplying blood to the penis, leading to stronger erections.

It has been shown in research studies that CIA is very effective at its prolonged inhibiting effects as well as having favorable safety and efficacy profile. CIA also has been found to have other mild vasodilating effects and is associated with hemodynamic effects that has shown to be worthy of possible research into utilizing CIA to combat high blood pressure and cardiovascular disease.

CIA has been loved by many researchers due to its long effective life of about 2-3 days per administration and this has led some researchers to favor CIA over other PDE5 inhibitors. CIA?s window for effectiveness per administration is much longer than other PDE5 inhibitors. CIA has been shown to last for up to 36 hours after administration and this is much longer than other PDE5 inhibitors that are effective for only about 4-5 hours after administration. Some researchers prefer this as they feel it works more naturally in test subjects and the effects of one dose can be felt for a couple days, making research more effective in some cases. Something to keep in mind with research of CIA and its effects on erection is that even with the use of CIA or other PDE5 inhibitors there it still requires sexual stimulation for the penis to develop an erection.

Although CIA's main known affect is its effect on erections, there are many more positives being seen in further research of this compound. CIA has also been shown to improve insulin's action, decrease circulating fatty acid levels in the body, modulate energy homeostasis in skeletal muscle and exert a beneficial effect on the cardiovascular system. CIA truly is a multi-faceted compound with a lot of positive research potential.

We are proud to offer you only the highest quality Tadalafil available for all your research needs.

Get it here >> Liquid Cia 30mL 30mg/ml


Ref:
1) Pharmacokinetics, pharmacodynamics, and efficacy of phosphodiesterase type 5 inhibitors.Sussman DO. Pharmacokinetics, pharmacodynamics, and... [J Am Osteopath Assoc. 2004] - PubMed - NCBI
2) Tadalafil alters energy metabolism in C2C12 skeletal muscle cells.Sabatini S, Sgr? P, Duranti G, Ceci R, Di Luigi L. Tadalafil alters energy metabolism in C2C12... [Acta Biochim Pol. 2011] - PubMed - NCBI
3) Assessment of the acute effects of tadalafil on the cardiovascular system based on examination of serum oxidative status and paraoxonase activity in men with erectile dysfunction: a preliminary study.Verit A, Savas M, Ciftci H, Aksoy N, Taskin A, Topal U. Assessment of the acute effects of t... [Int J Impot Res. 2010 Mar-Apr] - PubMed - NCBI
4) Five-year experience with tadalafil in the UK: an effective treatment for erectile dysfunction.
5) Dinsmore W.SourceRoyal Victoria Hospital, Grosvenor Road, Belfast, UK. wallace.dinsmore@royalhospitals.n-i.nhs.uk Five-year experience with tadalafil in the ... [Int J Clin Pract. 2009] - PubMed - NCBI


Liquid Cia 30mL 30mg/ml

Originally Posted by CEM Store

Tadalafil citrate (Cialis) is in a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors and to understand the actions of CIA you must first understand what a "PDE5" is and what the inhibitor's actions are.

PDE5 Inhibitors are drugs used to block the degrading action of PDE5 on cyclic GMP in the smooth muscle cells and blood vessels. A main action found in the use of PDE5 inhibitors are its effects in the lining of the blood vessels supplying blood to the penis, leading to stronger erections.

It has been shown in research studies that CIA is very effective at its prolonged inhibiting effects as well as having favorable safety and efficacy profile. CIA also has been found to have other mild vasodilating effects and is associated with hemodynamic effects that has shown to be worthy of possible research into utilizing CIA to combat high blood pressure and cardiovascular disease.

CIA has been loved by many researchers due to its long effective life of about 2-3 days per administration and this has led some researchers to favor CIA over other PDE5 inhibitors. CIA?s window for effectiveness per administration is much longer than other PDE5 inhibitors. CIA has been shown to last for up to 36 hours after administration and this is much longer than other PDE5 inhibitors that are effective for only about 4-5 hours after administration. Some researchers prefer this as they feel it works more naturally in test subjects and the effects of one dose can be felt for a couple days, making research more effective in some cases. Something to keep in mind with research of CIA and its effects on erection is that even with the use of CIA or other PDE5 inhibitors there it still requires sexual stimulation for the penis to develop an erection.

Although CIA's main known affect is its effect on erections, there are many more positives being seen in further research of this compound. CIA has also been shown to improve insulin's action, decrease circulating fatty acid levels in the body, modulate energy homeostasis in skeletal muscle and exert a beneficial effect on the cardiovascular system. CIA truly is a multi-faceted compound with a lot of positive research potential.

We are proud to offer you only the highest quality Tadalafil available for all your research needs.

Get it here >> Liquid Cia 30mL 30mg/ml


Ref:
1) Pharmacokinetics, pharmacodynamics, and efficacy of phosphodiesterase type 5 inhibitors.Sussman DO. Pharmacokinetics, pharmacodynamics, and... [J Am Osteopath Assoc. 2004] - PubMed - NCBI
2) Tadalafil alters energy metabolism in C2C12 skeletal muscle cells.Sabatini S, Sgr? P, Duranti G, Ceci R, Di Luigi L. Tadalafil alters energy metabolism in C2C12... [Acta Biochim Pol. 2011] - PubMed - NCBI
3) Assessment of the acute effects of tadalafil on the cardiovascular system based on examination of serum oxidative status and paraoxonase activity in men with erectile dysfunction: a preliminary study.Verit A, Savas M, Ciftci H, Aksoy N, Taskin A, Topal U. Assessment of the acute effects of t... [Int J Impot Res. 2010 Mar-Apr] - PubMed - NCBI
4) Five-year experience with tadalafil in the UK: an effective treatment for erectile dysfunction.
5) Dinsmore W.SourceRoyal Victoria Hospital, Grosvenor Road, Belfast, UK. wallace.dinsmore@royalhospitals.n-i.nhs.uk Five-year experience with tadalafil in the ... [Int J Clin Pract. 2009] - PubMed - NCBI


Liquid Cia 30mL 30mg/ml

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