Is Milk Thistle really effective?

min0 lee · 12-07-2004, 10:06 PM

I was wondering how effective milk thistle is, I have heard of a couple of people use it here. I have some liver damage and wondered if it really works?

bandaidwoman · 12-09-2004, 11:31 AM

It's only been shown to be liver protective in rats in terms of alcohol liver injury and no human clinical trials have been conducted that were substantial

The more common one is a report presented by Eagon and colleagues who used a rat model of alcohol-induced liver injury to further advance this literature. Rats fed 36% of their daily calories in alcohol were compared with rats fed an isocaloric but alcohol-free diet. Milk thistle was given in the diet of half of the animals. Histologic liver injury, both inflammatory and fibrotic, was ameliorated in the milk thistle-fed rats that had received the alcohol diet.

Long-term clinical trials using this compound vs placebo in chronic liver disease would be of great interest.

BoneCrusher · 12-09-2004, 11:59 AM

Quote:

Originally Posted by bandaidwoman

It's only been shown to be liver protective in rats in terms of alcohol liver injury and no human clinical trials have been conducted that were substantial

The more common one is a report presented by Eagon and colleagues who used a rat model of alcohol-induced liver injury to further advance this literature. Rats fed 36% of their daily calories in alcohol were compared with rats fed an isocaloric but alcohol-free diet. Milk thistle was given in the diet of half of the animals. Histologic liver injury, both inflammatory and fibrotic, was ameliorated in the milk thistle-fed rats that had received the alcohol diet.

Long-term clinical trials using this compound vs placebo in chronic liver disease would be of great interest.

Bandaidwoman thanks for being on this forum. You posts are always helpful.

Pepper · 12-09-2004, 12:27 PM

Quote:

Originally Posted by BoneCrusher

Bandaidwoman thanks for being on this forum. You posts are always helpful.

Amen to that!

min0 lee · 12-09-2004, 01:59 PM

Thank you!

12-07-2004, 10:06 PM	#1
min0 lee Senior Member Elite Member Join Date: Oct 2004 Location: The Bronx, NYC Posts: 38,792 Photos: 542	Is Milk Thistle really effective? I was wondering how effective milk thistle is, I have heard of a couple of people use it here. I have some liver damage and wondered if it really works?

12-09-2004, 11:31 AM	#2
bandaidwoman inadvertant tree hugger Elite Member Join Date: Dec 2003 Location: Atlanta, Georgia Posts: 728 Photos: 4	It's only been shown to be liver protective in rats in terms of alcohol liver injury and no human clinical trials have been conducted that were substantial The more common one is a report presented by Eagon and colleagues who used a rat model of alcohol-induced liver injury to further advance this literature. Rats fed 36% of their daily calories in alcohol were compared with rats fed an isocaloric but alcohol-free diet. Milk thistle was given in the diet of half of the animals. Histologic liver injury, both inflammatory and fibrotic, was ameliorated in the milk thistle-fed rats that had received the alcohol diet. Long-term clinical trials using this compound vs placebo in chronic liver disease would be of great interest. Official Race Member of the Crank Crushing Rednecks Eat more mud, mountain bike until you die! XX Feminine power

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12-09-2004, 01:59 PM	#5
min0 lee Senior Member Elite Member Join Date: Oct 2004 Location: The Bronx, NYC Posts: 38,792 Photos: 542	Thank you!