Second-messenger

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  1. #1
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    Second-messenger

    Can someone explain to me, Second-messeneger mechanisms of amino-acid based hormones.
    I just cant grasp it.
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  2. #2
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    Hormone (first messenger) binds to its receptor, which then binds to a G protein
    The G protein is then activated as it binds GTP, displacing GDP
    Activated G protein activates the effector enzyme adenylate cyclase
    Adenylate cyclase generates cAMP (second messenger ) from ATP

    cAMP activates protein kinases, which then cause cellular effects
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    I could help, I suppose but if I recall you said I had issues..........Hmmm........

    Actually you are better off reading this. I know a little bit on the subject but not enough to feel confidant I'd be giving you all proper info. http://web.indstate.edu/thcme/mwking...-hormones.html
    Last edited by Jodi; 06-06-2005 at 11:13 PM.



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    Quote Originally Posted by musclepump
    Hormone (first messenger) binds to its receptor, which then binds to a G protein
    The G protein is then activated as it binds GTP, displacing GDP
    Activated G protein activates the effector enzyme adenylate cyclase
    Adenylate cyclase generates cAMP (second messenger ) from ATP

    cAMP activates protein kinases, which then cause cellular effects
    thanks MP, with the chart and your info I think I have it now
    I highly recommend all IronMagLabs supplements!
    www.ironmaglabs.com

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DISCLAIMER:
All health, fitness, diet, nutrition & supplement information presented on IronMagazineForums.com's pages is intended as an educational resource and is not intended as a substitute for proper medical advice. We do not condone the use of anabolic steroids (AAS), all information about AAS is for educational and entertainment purposes only. Consult your physician or health care professional before performing any of the exercises, or following any diet, nutrition or supplement advice described on this website. As well as any exercise technique or regimen, diet, supplement, etc., particularly if you are pregnant or nursing, or if you are elderly or have chronic or recurring medical conditions. Discontinue any exercise that causes you pain or severe discomfort and consult a medical expert. The statements made about products have not been evaluated by the Food and Drug Administration (U.S.). They are not intended to diagnose, treat, cure or prevent any condition or disease. Please consult with your own physician or health care practitioner regarding the suggestions and recommendations made at IronMagazineForums.com. Neither the author of the information, nor the producer, nor distributors of such information make any warranty of any kind in regard to the content of the information presented on this website. Except as specifically stated on this site, neither IronMagazineForums.com, nor any of its authors or other representatives will be liable for damages arising out of, or in connection with the use of this site. This is a comprehensive limitation of liability that applies to all damages of any kind, including (without limitation) compensatory, direct, indirect or consequential damages, loss of data, income or profit, loss of or damage to property and claims of third parties. Sponsors pay for advertising space, we have no affiliation with the companies that have banners displayed on our websites. Please be advised it is your responsibility to check the laws that govern your country, state, or province in regards to items offered by some companies you may read about on this site.