min0 lee

I would imagine it because of their age they just felt better.
Ibuprofen or acetaminophen in long-term resistance training increases muscle mass/strength


Ibuprofen or acetaminophen in long-term resistance training increases muscle mass/strength

Taking daily recommended dosages of ibuprofen and acetaminophen caused a substantially greater increase over placebo in the amount of quadriceps muscle mass and muscle strength gained during three months of regular weight lifting, in a study by physiologists at the Human Performance Laboratory, Ball State University.

Dr. Chad Carroll, a postdoctoral fellow working with Dr. Todd Trappe, reported study results at Experimental Biology 2008 in San Diego on April 6. His presentation was part of the scientific program of the American Physiological Society (APS).

Thirty-six men and women, between 60 and 78 years of age (average age 65), were randomly assigned to daily dosages of either ibuprofen (such as that in Advil), acetaminophen (such as that in Tylenol), or a placebo. The dosages were identical to those recommended by the manufacturers and were selected to most closely mimic what chronic users of these medicines were likely to be taking. Neither the volunteers nor the scientists knew who was receiving which treatment until the end of the study.

All subjects participated in three months of weight training, 15-20 minute sessions conducted in the Human Performance Laboratory three times per week. The researchers knew from their own and other studies that training at this intensity and for this time period would significantly increase muscle mass and strength. They expected the placebo group to show such increases, as its members did, but they were surprised to find that the groups using either ibuprofen or acetaminophen did even better. An earlier study from the laboratory, measuring muscle metabolism (or more precisely, muscle protein synthesis, the mechanism through which new protein is added to muscle), had looked at changes over a 24 hour period. This “acute� study found that both ibuprofen and acetaminophen had a negative impact, by blocking a specific enzyme cyclooxygenase, commonly referred to as COX.

But that study looked at only one day. Over three months, says Dr. Trappe, the chronic consumption of ibuprofen or acetaminophen during resistance training appears to have induced intramuscular changes that enhance the metabolic response to resistance exercise, allowing the body to add substantially more new protein to muscle.

The amount of change was measured in quadricep muscles using Magnetic Resonance Imaging (MRI), the gold standard for determining muscle mass. The researchers now are conducting assays of muscle biopsies taken before and after the three-month period of resistance training, in order to understand the metabolic mechanism of the positive effects of ibuprofen and acetaminophen.

One of the foci of Ball State’s Human Performance Laboratory is the adaptation of the elderly to exercise. Another is the loss of muscle mass that takes place when astronauts are exposed to long-term weightlessness. This work has implications for both groups, says Dr. Trappe.

Source: Federation of American Societies for Experimental Biology

soxmuscle

less pain, produced better workouts thus the gains in size and strength?

Age: 20 | Height: 5'7" | Weight: 150 lbs.

Soxmuscle Presents: Westside Training

min0 lee

Could be.

fufu

Yeah but long term usage will fuck up your stomach!

fufu's 1337 Journal

Your diet will set you free.

lucifuge

i thought NSAID's actually inhibited muscle growth by less inflammation, yadda yadda yadda?

Destiny dressed you this morning my friend, and now Fear is trying to pull off your pants. If you give up, if you give in, you're gonna end up naked with Fear just standing there laughing at your dangling unmentionables!

-The Tick

hardasnails1973

Fucks up your liver depletes gluthione..why take NAC

EDIT: You need to place a link on your website to IronMagazine.com if you want to put a link in your sig.

Yanick

Acetaminophen is very hepatotoxic. Chronic usage is not something i would recommend unless one really needed it, and increasing muscle mass is not a necessity.

"...we have to remember that training is a complicated dance of stimuli and response. Our goal is to understand how to manipulate the stimuli in order to evoke the responses we desire." -Nathan J. Polenchek

fufu

welcome back bud.

fufu's 1337 Journal

Your diet will set you free.

hardasnails1973

Good to be back, but I hardly have time to post like I have been. I do alternative medicine, nutritional consulting,nutrient testing, HRT dealing specializing in thyroid and adrenal imbalances. So I am pretty busy these days Oh yes I have come leaps and bounds in these past few years. I also have been giving lectures to drs and other health professionals about presenting case studies I have worked on to getting people from a diseased state back to not normal but optimal health. Things have been really good..

EDIT: You need to place a link on your website to IronMagazine.com if you want to put a link in your sig.