Detoxin the Liver [Forum Archive]

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Detoxin the Liver

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Posted by: Pork Chop

What do you guys use?

Posted by: bigpapabuff

For a liver supplement I like to go with UDCA, works great for me.

Posted by: nyf1nest

Anything without too much milk thistle as it has been shown to make orals less potent

Posted by: SuperLift

Originally Posted by nyf1nest

Anything without too much milk thistle as it has been shown to make orals less potent

Interesting, I have never heard that before. Not saying its untrue though, I have always wondered that.

I like using milk thistle and liv52

Posted by: TGB1987

I love advanced cycle support by Ironmaglabs or Molecular nutrition Liver Stabil

Posted by: maniac0614

cycle support with liv52 DS

Posted by: vortex

Lots of water.

Posted by: Supermans Daddy

http://www.ironmagazineforums.com/an...pct-liver.html

Peace and Love

Posted by: misha2dope

Liv52 is awesome

Posted by: tballz

Originally Posted by bigpapabuff

For a liver supplement I like to go with UDCA, works great for me.

UDCA is one of the best liver protectors out there. It also lowers cholesterol.

Posted by: ctheman

Liv.52

Posted by: M4A3

Originally Posted by tballz

UDCA is one of the best liver protectors out there. It also lowers cholesterol.

You might find this interesting.

High dose UDCA therapy does not improve overall liver histology in obesity related hepatitis

High dose UDCA therapy does not improve overall liver histology in obesity related hepatitis

Posted by: Chino007

Liv52 got mine today!

Posted by: scwarzenegger

Mariatistel

Posted by: Yaz!

Originally Posted by bigpapabuff

For a liver supplement I like to go with UDCA, works great for me.

Originally Posted by tballz

UDCA is one of the best liver protectors out there. It also lowers cholesterol.

+ 100
Excellent choice,can i ask how you dose it - 2 times per week due to it's 3,5-3,7 days of half live or more ?

Originally Posted by nyf1nest

Anything without too much milk thistle as it has been shown to make orals less potent

Originally Posted by SuperLift

Interesting, I have never heard that before. Not saying its untrue though, I have always wondered that.

I like using milk thistle and liv52

It's true but doesn't specifically reduces the potency of oral AAS - it inhibits with the AR.

Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP.
Zhu W, Zhang JS, Young CY.

Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic/Foundation, Rochester, MN 55905, USA.

Abstract
A number of reports have shown that the polyphenolic flavonoid silymarin (SM) is an effective anticancer agent. Agents with novel mechanisms of blocking androgen receptor (AR) function may be useful for prostate cancer prevention and therapy. Previous studies showed that silibinin (SB), the major active component of SM, could inhibit cell proliferation of a human prostate cancer cell line, LNCaP, by arresting the cell cycle at the G(1) phase without causing cell death. This study further delineates the potential molecular mechanism by which SM and SB exhibit antiproliferative effects on androgen-responsive prostate cancer cells by inhibiting function of the AR. We observed that SM and SB inhibited androgen-stimulated cell proliferation as well as androgen-stimulated secretion of both prostate-specific antigen (PSA) and human glandular kallikrein (hK2). Additionally, for the first time, we show that an immunophilin, FKBP51, is androgen regulated and that this up-regulation is suppressed by SM and SB. We further demonstrate that transactivation activity of the AR was diminished by SM and SB using gene transfer of PSA promoter and hK2 androgen-responsive element constructs. However, expression and steroid-binding ability of total AR were not affected by SM in western blotting and ligand-binding assays. Intriguingly, we found that nuclear AR levels are significantly reduced by SM and SB in the presence of androgens using western blotting assay and immunocytochemical staining. This study provides a new insight into how SM and SB negatively modulate androgen action in prostate cancer cells.

Originally Posted by M4A3

You might find this interesting.

High dose UDCA therapy does not improve overall liver histology in obesity related hepatitis

Actually i've read this study a couple of times already some months now but can't say it's any suprise at all. UDCA seems to have a completely different mechanism of action, that's why it is the only drug currently approved for some types of bile induced cirrhosis and not any form of hepatitis. The reason this drug is excepetional, it's because it is unique when it comes to prevention of 17aa oral AAS induced cholestasis.

P.S. Terribly sorry for posting the whole abstract but due to low post count is seems that i can't post a link.

Posted by: GMO

Water and clean diet.

Posted by: tballz

Originally Posted by Yaz!

+ 100
Excellent choice,can i ask how you dose it - 2 times per week due to it's 3,5-3,7 days of half live or more ?

You are right on. I dose twice a week. Just 250mg each time for a total of 500mg/week.

Do you think that's sufficient or should I up the dosage?

Posted by: Yaz!

Originally Posted by tballz

You are right on. I dose twice a week. Just 250mg each time for a total of 500mg/week.

Do you think that's sufficient or should I up the dosage?

In this dosing protocol the usual range is 500-1500mg per week.
What do your bloodwork say ? How do you respond with this dosing ?

Posted by: pitbullguy0101

got some shit from n2bm for my liver...its getting hard to take this many pills tho

Posted by: lifterjaydawg

definitely like using udca, great for cleaning out the liver. I use about 1000mg per week.

Posted by: Pork Chop

great info gius and thanks to all for chiming in. Has anyone ever used the inject version of Essentiale Forte?

Posted by: IronPotato

lots of water and perhaps some sam-E and a little m thistle along with 600mg of NAC

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Detoxin the Liver

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