Said it doesn't work as good for white bro's. But progesterone worked better.
Testosterone Tested as Male Contraceptive
Study Shows Monthly Injections in Men Can Prevent Partners' Pregnancies
by Salynn Boyles
WebMD Health News
Reviewed by Brunilda Nazario, MD
May 6, 2009 -- After decades of delay, hormonal birth control for men may be a step closer to reality.
Monthly injections of a testosterone-based contraceptive were 99% effective for preventing partner pregnancy in what researchers say is the largest trial ever of a hormone-based male birth control approach.
Testosterone therapy is usually given to men to treat a condition resulting from a lack of testosterone. In men, testosterone controls sperm production, erections, and sex drive.
The study looked at fertile men, and treatment with testosterone was used to decrease sperm production. Testosterone treatment is known to decrease hormones of the brain that signal the testes to produce sperm.
Just over 1,000 Chinese men between the ages of 20 and 45 who had fathered at least one child within two years of enrollment took part in the study, which was published in The Journal of Clinical Endocrinology & Metabolism.
The search for a commercially viable male equivalent of the pill has been stalled in recent years, largely due to lack of interest by the pharmaceutical industry, says Elaine Lissner, who directs the Male Contraception Information Project.
"There has been a lot of consolidation within the industry, and several companies that were working on hormonal birth control for men abandoned development even though their studies were positive," she tells WebMD.
Companies lost interest, she says, because they concluded that there was not enough of a market for male birth control that required implants or frequent injections.
An oral male pill is not likely because testosterone is not as effective when taken by mouth and it can be toxic to the liver.
Studying Testosterone's Effects
The men in the Chinese study received monthly injections of a form of testosterone known as testosterone undecanoate (TU).
Lead researcher Yi-Gun Gu, MD, of Beijing's National Research Institute for Family Planning tells WebMD that while the contraceptive was found to be highly effective in the study, TU alone is not likely to be used in non-Asian populations.
Asian men seem to respond well to testosterone as a form of contraception, while studies in white men have shown it to be much less effective.
The reasons for this are not clear, but Gu tells WebMD that any hormonal birth control developed for non-Asian men is likely to include another hormone -- progestin.
Studies have shown the testosterone-progestin combination to be very effective in suppressing fertility in white men.
The Chinese men in Gu's study took monthly injections of 500 milligrams of TU in tea seed oil for 30 months. This formula is not available in the U.S. and is indicated to treat low testosterone levels with injections typically given every three months.
Over the course of the trial, nine pregnancies occurred in the partners of 1,045 study participants, or roughly one pregnancy for every 100 men.
There was no evidence of major side effects, and all but two of the men in the study returned to normal fertility after stopping the injections. The average time it took for the men to return to normal fertility was around six and a half months.
Gu says more study is needed to examine the long-term safety of the TU treatment.
In an editorial accompanying the study, male fertility researcher David Handelsman, MD, of the University of Sydney writes that several other promising male contraceptives are under development with little help from the pharmaceutical industry.
He argues that there is a clear need and demand for a practical hormonal contraceptive option for men.
"Whatever the reasons for the strike by large pharmaceutical companies ... the disconnect between the lay and medical perception of both a need and a niche for [hormonal male contraception], on the one hand, and the failure of the pharmaceutical market to deliver a product, despite the demonstration of feasibility, is puzzling, indeed," he writes.
Lissner says governments and nonprofit foundations are taking the lead in developing new hormonal and nonhormonal male birth control.
She points out that the Gates Foundation has made contraceptive development one of the four pillars of its new reproductive strategy.
"We are very fortunate to have a more promising political environment than we have had," she says. "This is a good time for male contraception, but I don't think we can count on the pharmaceutical companies to do this."
Posted by: BP2000
Next question is how long you have to be on test for this to be effective? I know in women they take the pill it's effective in a month. And wouldn't Test CYP. or any test work since test is test? I think they did UNDEC. because of it's super long life. You can inject only 1 time every 12 weeks.
Posted by: Imosted
Bro i was on 1 gram of test-week, when my wife got pregnant.
Posted by: .V.
Don't count on it guys. Sure it reduces the size of testicles and stops natural test production. However, I was on for over 3 years...nonstop and Mrs.V. was on a low dose of progestrone, estrogen, testosterone...with a little prop too... and we ended up with an unexpected pregnancy. This was after reaching our 40s and we thought she had reached menopause AND she'd had a tubal ligation after losing the twin girls a few years ago in the 7th month. We lost the baby, and heartbreaking as this was it's probably for the best since it would have likely been born with 9 heads or something.
That said, although exogenous test is somewhat effective as a male contraceptive, you'd best not count on it as your only method of BC. As I posted, we had 3 methods in place...one supposedly permanent and 100% effective... still got pregnant.
Posted by: red rocket
My wife concieved our daughter when I was on, and a good buddy of mine recently achieved the same.
Posted by: btex34n88
yeah test, tren, dbol apparently doesnt prevent pregnancy's either lol 2nd one
Posted by: Glycomann
I keep getting this image of these juiced up sperm plodding up the uterus huffing and puffing like Jay Cutler walking up 4 flights of stairs on his bulk.
Posted by: BP2000
Originally Posted by btex34n88
yeah test, tren, dbol apparently doesnt prevent pregnancy's either lol 2nd one
Was this without using HCG during cycle or with?
Posted by: BP2000
Originally Posted by Imosted
Bro i was on 1 gram of test-week, when my wife got pregnant.
Well this test was done on Chinese men. It says white responded better with progesterone. I think Deca is a derivative of that.
Posted by: World-Pharma.org
Originally Posted by Imosted
Bro i was on 1 gram of test-week, when my wife got pregnant.
bump...good post..its will not stop you to make kids..
Posted by: heavyiron
My wife got pregnant while I was on test. Its a no go for birth control.
Posted by: HH25
Posted by: BP2000
Originally Posted by BP2000
Well this test was done on Chinese men. It says white responded better with progesterone. I think Deca is a derivative of that.
Anyohe conceive on Deca or NPP?
Posted by: MrSaturatedFat
All this baby talk is scaring the shit outta me!!
Im on test/deca right now and cant stop banging the girl I'm seeing right now. Back to condoms for me
Posted by: Buzzard
Originally Posted by Imosted
Bro i was on 1 gram of test-week, when my wife got pregnant.
Were you using HCg?
Posted by: SUPERFLY1234
Originally Posted by Imosted
Bro i was on 1 gram of test-week, when my wife got pregnant.
hmm, that weird most guys have lower sperm count or lots of dead ones. when they are on
Posted by: Imosted
Originally Posted by Buzzard
Were you using HCg?
i have never used hcg in my life, i was on a 20 week test-e only cycle(i didn't have money for anything else...)
Posted by: BP2000
Originally Posted by MrSaturatedFat
All this baby talk is scaring the shit outta me!!
Im on test/deca right now and cant stop banging the girl I'm seeing right now. Back to condoms for me
The article say's DECA is better than test. Do you have any libio issues w/ Deca, or you taken any caber?
Posted by: MrSaturatedFat
Originally Posted by BP2000
The article say's DECA is better than test. Do you have any libio issues w/ Deca, or you taken any caber?
I had no libido issues so far while on Deca. In fact, its been quite the opposite. Very horny all the friggin time, lol. I took .5mg of caber 1x week since the beginning of the cycle. Here is what my Prolactin did; EDIT: 8 weeks in.
But to many people on here saying they got the gf/wife preggo while on cycle. I'm not going to risk it.
Posted by: btex34n88
Originally Posted by BP2000
Was this without using HCG during cycle or with?
without
Posted by: bigboi73
Originally Posted by Imosted
Bro i was on 1 gram of test-week, when my wife got pregnant.
Got my wife pregnant the first time we had sex when she went off the pill while I was on a very high test cycle (6 weeks in). She told me it would take a 6 months to a year for her to get pregnant. Very first fucking try. Still praying to God that the baby will be perfectly normal, due in March.
Posted by: aminoman74
Iv always have been on big cycles when my wife always got pregnant