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Some cravings are leaving |
Originally posted by Dr. Pain WELL I HOPE TO HELL SHE TIRES OF SUGAR SOONER THAN THAT !!! DP |
This meal got pushed back|
Originally posted by Dr. Pain May 5th that was explosive, DP |
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Originally posted by Dr. Pain Actually, when bulking I eat more like 140 F a day.... The main reason is that when I gave up the bulk of sugars and starches in my program over 4 years ago, after being fat all my life, I became lean...I also became a fat "Oxidizer" ...Not having sugars to rely on, my body readily accepts fat as fuel....no loss of energy (increase actually)...and hopefully when I run out of dietary fat, my body says "Hey, we like fat....let's burn some of this guys bodyfat....(and must be working, I'm always cut)"
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My tree trunk leg vascularity has returned....since it wasn't warm at all......I'm positive that means a MM or two change in my legs......they usually run 5-6....I'm afraid I've been at 7-8 since the bulk....lots of cuts always, but veins are so cool 
(more cheese..stopping now)|
Originally posted by w8lifter Flax Seed and Immune System Flaxseed contains two components that favourably affect the immune system: alpha-linolenic acid (ALA), an essential omega-3 fatty acid, and lignans, a type of phytoestrogen. These components affect immune cells and mediators of the immune response such as eicosanoids and cytokines. ALA, for example, suppresses the proliferation of peripheral blood mononuclear lymphocytes and the delayed hypersensitivity response to certain antigens.1 Recent research suggests that ALA and lignans in flaxseed modulate the immune response and may play a beneficial role in the clinical management of autoimmune diseases.2, 3 Flaxseed Effects on the Immune System The ALA component of flaxseed influences immunity -- the body's ability to defend itself successfully against foreign substances -- through its effects on membrane phospholipids and the production of eicosanoids and cytokines. Lignans influence certain mediators of the immune response. ALA and other omega-3 fatty acids influence the immune response by altering the fatty acid composition of membrane phospholipids, which in turn significantly affects eicosanoid production. ALA in flaxseed increases phospholipid ALA, EPA and DHA levels in mononuclear cells,4 neutrophils,5 lipoproteins,5, 6 and platelets7. This change in membrane phospholipid content results in reduced biosynthesis of arachidonic acid from linoleic acid and decreased production of the proinflammatory eicosanoids, leukotriene B4 (LTB4) and thromboxane A2 (TXA2),9 shown in the Figure. Increasing the ALA and omega-3 fatty acid content of membrane phospholipids enhances the biosynthesis of prostaglandin I3 (PGI3) and other eicosanoids of the 3- and 5-series that are less inflammatory.10 Eicosanoids are a group of biologically active compounds derived from polyunsaturated fatty acids such as arachidonic acid.9 In rats, mice and cynomolgus monkeys, ALA suppresses tissue levels of arachidonic acid and the biosynthesis of eicosanoids, but not to the same extent as EPA and DHA.8, 11, 12 In humans, prostaglandin biosynthesis is also influenced by ALA intake. In one study, six healthy women consumed isocaloric formula diets providing a constant amount of linoleic acid and different amounts of ALA (0%, 4% and 8% of total energy); each formula diet was consumed for two weeks. Total prostaglandin biosynthesis decreased nearly 50% at the highest ALA intake level.13 In a study of a single male subject, the urinary excretion of metabolites of TXA2 and PGI2 decreased 34% during the seven week period in which the subject consumed a mix of flaxseed and canola oils.14 In another study, PGE2 and thromboxane B2 production was inhibited significantly when subjects (28 healthy men) consumed a flaxseed oil-based diet for eight weeks.4 Cytokines are soluble proteins liberated from immune cells in response to injury, infection or exposure to foreign substances.15 Two cytokines that contribute to inflammation are tumour necrosis factor (TNF) and interleukin-1 (IL-1). Both are present in rheumatoid joints and contribute to the tissue pathology of rheumatoid arthritis;16 and they stimulate the release of platelet-activating factor, a potent mediator of inflammation. The production of TNF and IL-2 by macrophages is influenced by dietary ALA and the ALA to linoleic acid ratio.17 Consumption of a flaxseed-oil based diet for eight weeks, for example, resulted in an inhibition of TNF and IL-1 34 production of about 77-81% in a study of 28 healthy men.4 Several studies have demonstrated significant reductions in TNF and IL-1 levels in humans consuming omega-3 fatty acids.18 Flaxseed may prove useful in the nutritional management of patients with autoimmune diseases. For example, systemic lupus erythematosus (SLE) is an inflammatory disease that occurs mainly in young women. It is characterized by a variety of clinical findings, including inflammation of the kidney (nephritis). Studies show that patients with SLE exhibit increased production of platelet-activating factor (PAF), a mediator of immune response and promoter of platelet aggregation.19 Dietary flaxseed has provided significant benefits in animal models of lupus nephritis and in patients with this condition.3 In one study of nine patients with lupus nephritis, PAF-induced platelet aggregation was inhibited and renal function improved when subjects consumed 15 to 45 g flaxseed/day for four weeks.20 The lignan component of flaxseed is believed to be responsible for this effect.21 Flaxseed favourably influences immune response. The flaxseed component, ALA, alters membrane phospholipids, inhibits arachidonic acid biosynthesis from linoleic acid, inhibits the production of proinflammatory eicosanoids from arachidonic acid, and suppresses lymphocyte proliferation and cytokine production.22, 23 Flaxseed lignans are potent inhibitors of platelet-activating factor, a mediator of inflammation.3 Through these effects, flaxseed has the potential to be used for the treatment of disorders characterized in part by activated lymphocytes and a hyper-stimulated immune response. Such disorders include rheumatoid arthritis, psoriasis, multiple sclerosis and systemic lupus erythematosus.3, 24 References 1. Kelley DS, et al. Am J Clin Nutr. 1991;53:40-46. 2. Blackburn GL. Proc Soc Exp Biol Med. 1992;200:183-188. 3. Parbtani A and Clark WF. In: Flaxseed in Human Nutrition. Cunnane SC and Thompson LU, eds. Champaign, IL: AOCS Press, 1995, pp. 244-260. 4. Caughey GE, et al. Am J Clin Nutr. 1996;63:116-122. 5. Mantzioris E, et al. Am J Clin Nutr. 1994;59:1304-1309. 6. Cunnane SC, et al. Am J Clin Nutr. 1994;61:62-68. 7. Ferrier LK, et al. Am J Clin Nutr. 1995;62:81-86. 8. Whelan J, et al. Lipids. 1991;26:119-126. 9. Wallace JL and Chin BC. Proc Soc Exp Biol Med. 1997;214:192-203. 10. Calder PC, et al. Immunology. 1992;75:108-115. 11. Hwang D. FASEB J. 1989;3:2052-2061. 12. Wu D, et al. Am J Clin Nutr. 1996;63:273-280. 13. Adam O, et al. J Lipid Res. 1986;27:421-426. 14. Ferretti A and Flanagan VP. Prostaglandins Leukot Essent Fatty Acids. 1996;54:451-455. 15. Abbas AK, et al. Cellular and Molecular Immunology. Philadelphia, PA: W. B. Saunders Company, 1994, pp. 9-10, 240-260. 16. Arend WP and Dayer J-M. Arthritis Rheum. 1990;33:305-315. 17. Watanabe S, et al. Life Sci. 1991;48:2013-2020. 18. Endres S. Lipids. 1996;31(Suppl):S239-S242. 19. Tetta C, et al. Int Arch Allergy Appl Immunol. 1990;91:244-256. 20. Clark WF, et al. Kidney Int. 1995;48:475-480. 21. Ingram AJ, et al. Am J Kidney Dis. 1995;25:320-329. 22. Leaf A and Weber PC. N Engl J Med. 1988;318:549-557. 23. Nair SSD, et al. J Nutr. 1997;127:383-393. 24. Blok WL, et al. J Nutr. 1996;126:1515-1533. |
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Originally posted by Mudge The below study suggests ground flaxseed is on level with nolvadex/tamoxifen. Thompson LU, Li T, Chen J, Goss PE Nutritional Sciences, University of Toronto, Toronto, ON, Canada; Medical Oncology, Princess Margaret Hospital, Toronto, ON, Canada Epidemiological studies and biological properties of mammalian lignans derived from plant precursors (phytoestrogens) suggest that they may have anticancer potential. Flaxseed, the richest source of mammalian lignan precursors, has previously been shown to reduce the mammary tumor number and growth of established tumors in rats. The aim of this study was to examine, in a randomized double blind, placebo controlled, prospective clinical trial, the effects of dietary flaxseed on tumor biology, urinary lignan excretion and side effects in patients with newly diagnosed breast tumors. Patients were randomized to either a 25g flaxseed containing muffin (6 pre-, 17 post-menopausal) or a control (placebo) muffin (4 pre-, 12 post-menopausal). At initial diagnostic core biopsy and at definitive surgery, (a) tissues were analyzed for rate of tumor cell proliferation(Ki67 labeling index and score), c-erB-2 expression, and estrogen (ER) and progesterone (PR) receptor levels, (b) 24-hr urine samples were collected and analyzed for lignans, and (c) 3-day diet records were analyzed for nutrient intake. Side effects were monitored. Mean treatment times were 39 and 38 days in the placebo and flaxseed groups, respectively. In postmenopausal women, significant reductions (21-33%) in Ki67 labeling index (p<.036) and scores (p<.029) and in the c-erB-2 expression (p<.040) were observed in the flaxseed group but not in the placebo group. These changes are comparable to those seen with tamoxifen using similar study protocol. No significant differences in the ER and PR levels and in caloric and macronutrient intakes were seen between groups and between pre- and post- treatment periods. Significantly higher post-treatment urinary lignan excretion was observed in the flaxseed group compared with placebo and with pre-treatment levels. No significant adverse effects of flaxseed were reported. This study showed, for the first time, the potential of dietary modification with flaxseed and its components such as the lignans, in reducing tumor growth in patients with breast cancer comparable to the effects seen with preoperative tamoxifen. They used ground flaxseeds in this study (flax meal). You can buy flax meal but it goes bad quickly so the best way in my opinion is grind them in a coffee grinder and throw them in your oatmeal. Before grinding the seed's shell protects it and it will keep that way for a long time--once ground I think you only have roughly 48 hours (could be wrong on that--its something like that) before they go rancid--its cheaper and easier to just buy the seeds and grind them then to buy flaxseed meal Will Brink:" The implication of the above study is obvious for women, but men reading this should see the clear potential benefits: flax seeds and high lignan flax oil may be a natural anti estrogen as powerful as Nolvadex and would explain why I have seen reductions in gyno in men taking high amounts of flax oil" |
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Originally posted by Dr. Pain 1) Went to 12 whites, with jumbos, this is a whackload of eggwhite, but it made no sense to leave 2 in the box...now I have to find the research on avidin or biotin or whatever...to see if this is a bad idea (no yolks) |
Thanks but don't you think I know that by now.
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Originally posted by Jodi Thanks but don't you think I know that by now. |
LOL
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Originally posted by The_Chicken_Daddy Only if they're raw. Cooked eggs have the avidin protein deactivited so doesn't hinder biotin absorption. But be aware of the sodium intake from that many whites - especially if you're eating other salty foods and have a family history of high BP. |
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Originally posted by Fit Freak DP...I started to follow this...I'm getting some gr8 info from it...VERY NICE journal
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