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Leptigen Hath Arrived


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Posted by: Twin Peak

Leptigen is now available for sale:

Earlier this week, the shipping of Avant Labs LeptiGen II, the long-awaited Cellular Metabolic Optimizer, has finally begun. For those of you who are unfamiliar, LeptiGen II is designed to deceive one’s body into thinking it is being fed without necessitating the calories traditionally required to elicit the hormonal response typified by the fed state. The dieter can now bypass the detrimental effects of the starvation response—metabolic downregulation and a in plateau fat loss, increased loss of Lean Body Mass, surge in appetite, fatigue, etc.—without the implementation of frequent, and often progress-hindering, refeeds. While other supplements offer only to camouflage the secondary effects of dieting, LeptiGen II prevents the actual genesis of these obstacles through the manipulation of their hormonal source, before they can become a hindrance to the realization of one’s goals.

For those interested in more information regarding this revolutionary product, there is a live chat tomorrow, July 24th, with the creator, Par Deus. For information regarding this chat, please refer to the thread on the Avant Forum. Please Note: Only registered board members may participate in this chat. We invite everyone to sign up today and pose your questions to the supplement designer.

As well, you might be interested in following DaMayor's journal where he will be tracking his dieting progress while using it.



Posted by: Twin Peak

Oh, and the dosing protocol:

Dosing:

Males

<6% BF = 5 tablespoons/day

6-9% BF = 4 tablespoons/day

9-12% BF = 3 tablespoons/day

12-15% BF = 2 tablespoons/day

15-20% BF = 1 tablespoons/day

>20% BF = 0



Females

Add 1 tablespoon to corresponding male dosages. Do not use until under 25% BF, unless you have dieted for at least 8 weeks.

This dosing protocol assumes a moderate (500 calorie) deficit. Add 2 tablespoons per 500 calories below this moderate deficit.


These are general dosing guidelines, and may vary depending on the length of ones diet, and ones geno and phenotypes.

Bottom line is the farther you are UNDER your setpoint the greater the dose you will need.

Also, each serving should be taken about halfway between each meal.



Posted by: DaMayor

This is going to be cool.



Posted by: Jodi

Good Luck DM! I'll be watching.

I can't wait to see the progress and results of this test.



Posted by: DaMayor

Quote:
Originally posted by Jodi
Good Luck DM! I'll be watching.

I can't wait to see the progress and results of this test.

Neither can I. I am really looking forward to an "after" pic......this "before" deal sucks!

For the record...we're taking this seriously.......



Posted by: dg806

Yeah good luck DM!!



Posted by: DaMayor

A Belated "thanks", DG.

I can't believe folks over here aren't raving about this product like the guys over at Avant......It's like a feeding frenzy over there.



Posted by: Dante B.

Quote:
I can't believe folks over here aren't raving about this product like the guys over at Avant......
My friend, it's only a matter of time



Posted by: Pepper

TP,

Not to sound like DaMayor but how quickly are orders shipping?



Posted by: Twin Peak

You do dound like him.

Generally, they ship the same or next day.



Posted by: DaMayor

Hey hey! Back off of DaMayor,would you? I can't help my enthusiasm, otherwise defined as "impatience" per TP.

You thinking about making a purchase, Pepper? I would strongly recommend it.....I think you would appreciate the appetite suppressant qualities, if nothing else.



Posted by: OceanDude

How about some general questions before hand?

What are active ingredients, is it absolutely safe in humans and where was it tested?



Posted by: Twin Peak

Quote:
Originally posted by OceanDude
How about some general questions before hand?

What are active ingredients, is it absolutely safe in humans and where was it tested?
There are about forty or fifty, they are posted at Avant.

It is currently being tested on one guniea pig named DaMayor. And about 150 other people who have paid for it.

All ingredients are naturally occuring and found in normal supplements and foodstuffs.

Many are things like:

BCAAs
Galactose
Creatine
glutamine

and on and on.

It is the proprietary blend, and specific quantities that make it what it is.



Posted by: freeman1504

I'd love to try this stuff but just can't afford it right now. I'll be a guinea pig if you'd like

or I'll just take free samples hahaha god damn I hate being a broke-ass college student!



Posted by: Twin Peak

Freebees have officially ended, but thanks for trying.



Posted by: freeman1504

haha gotta give it a shot



Posted by: OceanDude

Quote:
Originally posted by Twin Peak
There are about forty or fifty, they are posted at Avant.

It is currently being tested on one guniea pig named DaMayor. And about 150 other people who have paid for it.

All ingredients are naturally occuring and found in normal supplements and foodstuffs.

Many are things like:

BCAAs
Galactose
Creatine
glutamine

and on and on.

It is the proprietary blend, and specific quantities that make it what it is.
Sounds pretty basic then - no fancy thryoid hormonal precursors? And I am not so confident DaMayor counts as "Human"




Posted by: Twin Peak

I suppose the ingredient list may be "basic" but it ain't anything "typical" or "average." Here is the full list:

http://www.avantlabs.com/product.php?productID=5

galactose
BCAA's
IP6
Betaine HCl
glucosamine HCl
Glutamine
creatine pyruvate
Lecithin
sodium acetate
histadine
arginine
Leucine
Taurine
Magnesium citrate
calcium lactate
n-acetyl-cysteine
d,l Phenylalanine
d-mannose
Acetyl-l-cartinine
n-acetyl-glucosamine
vitamin E acetate
l-carnitine
inositol
Glycine
salt (iodized, K+)
calcium pantothenate
Proline
Citrulline
n-acetyl-tyrosine
vit C/ascorbate
GABA
simmondsin
5-HTP
alpha lipoic aicd
synephrine
Zinc
folic acid 10% w/tmg
biotin 1%
selenomethionine



Posted by: OceanDude

Thanks.
Reminds me of a super reincarnation of the old original formula "Hot Stuff" - everything but the kitchen sink. I find the inclusion of the following interesting:
histadine
n-acetyl-cysteine
d,l Phenylalanine
n-acetyl-glucosamine
n-acetyl-tyrosine
simmondsin
5-HTP
synephrine
selenomethionine

Will keep my eye out for published results.



Posted by: Twin Peak

Please don't ever again compare it to hotstuff.

That took various supplements and chaotically threw them together, in insufficient doses, to produce the product.

These macro and micro nutrients were each individually selected, for a specific reason or reasons at a specific dosage to achieve specific results.



Posted by: Par Deus

[quote]Originally posted by OceanDude
Thanks.
Reminds me of a super reincarnation of the old original formula "Hot Stuff" - everything but the kitchen sink. I find the inclusion of the following interesting:

histadine

>>> Histamine precursor -- increases leptin sensitivity -- H1 antagonism prevents the effects of leptin on appetite and energy expenditure

n-acetyl-cysteine

>> Thiol -- necessary for cellular REDOX mediation, which is necesary for proper signal transduction (basically, keeps the oxidation from high cellular metabolism from shutting things down (to prevent cell damage)

d,l Phenylalanine

>>>> neurotransmitter precursor -- dopamine and endorphin systems -- signals the fed state, particularly in the CNS


n-acetyl-glucosamine

>>>> hexosamine pathway -- probably the stongest nutrient signalling pathway mediating leptin expression.

n-acetyl-tyrosine

>>> higher uptake version of tyrosine -- dopamine and NE precursor -- signals the fed state, particularly in the CNS


simmondsin

>>> works via CCK, which is synergistic with leptin, in regard to energy expenditure and appetite.


5-HTP

>>> serotonin precursor -- increases leptin


synephrine

>>> increases leptin sensitivity

selenomethionine

>>> thiol -- see NAC



Posted by: DaMayor

Since nobody else said it....Thanks Par.

And Welcome to IM, by the way.



Posted by: Molehonea

I am about 18% body fat. Will this help and is there any results from testing?



Posted by: DaMayor

IMO, I think it would.

We're currently in the Beta testing mode.....check out my jounal. It's boring, but it might answer your questions.



Posted by: Par Deus

People have only had it about 7-10 days, but we have collected quite a bit of the initial feedback here:

http://www.mindandmuscle.net/feedbac...hp?productID=5



Posted by: Jodi

I can't find this answer and I'm not sure if its been asked so.

Is there any harm in mixing the LeptiGen in some crystal light the night before to be packed with my food and that way have it all ready to go?



Posted by: Par Deus

That is fine.



Posted by: Pepper

Quote:
Originally posted by Jodi
I can't find this answer and I'm not sure if its been asked so.

Is there any harm in mixing the LeptiGen in some crystal light the night before to be packed with my food and that way have it all ready to go?
Good question...I have one too...are there any supps that should not be taken with LeptiGen? Specifically ephedra?



Posted by: Jodi

Pepper did you order some?

BTW - Ab-solved Rocks!



Posted by: Pepper

I did. Drinking my second portion right now.

I am ordering Ab-solved for my wife. I think she is exactly the person it is made for. If it works, I will be "THE MAN" around here! I am still a little far away to expect Ab-solved to do me much good.



Posted by: Twin Peak

Quote:
Originally posted by Pepper
Good question...I have one too...are there any supps that should not be taken with LeptiGen? Specifically ephedra?
No.



Posted by: Jodi

Quote:
Originally posted by Pepper
I did. Drinking my second portion right now.

I am ordering Ab-solved for my wife. I think she is exactly the person it is made for. If it works, I will be "THE MAN" around here! I am still a little far away to expect Ab-solved to do me much good.
Ab-solved worked great for me. 1" in 3 weeks.

That's what I'm going to do for Christmas, buy my sisters each a bottle of Ab-Solved. J/K

but might not be a bad idea come to think about it.

Good Luck Pepper, I just took my first dose tonight



Posted by: freeman1504

I think I'm giving this stuff a try when I get my next paycheck...to make sure I have enough $$ to cover it.

I think I may pick up some ab-solved too.



Posted by: Tkarrde

Quote:
Originally posted by Pepper
Good question...I have one too...are there any supps that should not be taken with LeptiGen? Specifically ephedra?
Ephedra and the like should be fine.

The only thing you should be mindful of is that, full 60gram LeptiGen dosing contains:
Synephrine: 40mg
Simmondsin: 400mg



Posted by: blinkboy99

when do u guys take ur doeses?

also what r the main beinfets? ive read it will increase leptin, reduce hunger....



Posted by: Jodi

You can read about it Here



Posted by: Pepper

TP asked for my Leptigen feedback..so here goes...

I started taking the product on Thursday, 7/31. I have been taking 2 doses a day at 2 TBLS each. I have mixed it with diet iced tea, rasperry crystal light and pink lemonade crystal light. The taste of this product is hard to miss in ANYTHING it is mixed into. I think though, that the smell of the product is so bad, that the foul taste is exagerated as I have "flash backs" to the smell. In any event, the taste is not so bad as to prevent me from taking my dose when the time comes.

I spent the weekend thinking that the product was NOT helping my appetite. However, yesterday I was looking at my totals as logged in Pocket Diet Tracker software and was surpised to see how low my calories were. I was at about 75% of my typical calories on each day.

Today I noticed a complete lack of appetite. I almost forgot breakfast and, for the first time since I went on this diet, I forgot meal 2. Meal three...I finally decided that I simply had to have something so I made a SANS Infusion shake, drank half of it and put it in the frig. Unbelievable.

I have noticed the rumbling in my stomach after taking it. Yes, the reported increase in gas has happened too. However, these side effects are very minor.

I think the main thing I learned from reviewing my macros is the drastic drop in carbs. I simply do not crave them and therefore do not seek them out. My carb totals were ridiculously low Saturday. So low, I intentioally ate a slice of bread at Outback to get the % up a bit.

So, after about five days, I'd have to say this product works. The only real negative is the taste, but that is a price worth paying.

More later in the week.

For those of you who do not know me, I am 6-4, 290 lbs, down from 335 or so. Normally cals are around 2800 with a 50/30/20 split. (However, my "cheat" day Saturday barely hit 2800.)



Posted by: OceanDude

Pepper, would you say the taste is worse than the taste of the predigested proteins and good amino acids or better than? I can barely down the full predigested proteins if I drink it in one full swallow, don't breath and then drink a lot of fresh water right behind it.

I am not sure that I need any kind of hunger suppression though since I do not have a carb addiction at all and already have to force myself to eat my full 6 meals since I pretty much feel full all the time now. I do this with super high fiber foods and 20-25% EFA poured in to the food as a supliment. I think the EFA produces a fair number of lipids in the bloodstream and it signals the brain to produce "no hungry" hormones .



Posted by: Pepper

Oh, OD reminded me, I started taking Fish Oil at about the same time. I wonder if this is not helping with the appetite suppression.

OD, I have not taken the products you describe, so I can't help you there.



Posted by: Par Deus

Fish oil is great stuff, and increases leptin sensitivity, but PPAR-alpha agonism increases uptake of FFA's into the cell (also increases glucose uptake), so unless you are taking a ton, it is not going to elevate plasma FFA's, much, if at all.

Plus, I have never heard of anyone noticing any sort of drastic reductions in appetite and hunger from fish oil.



Posted by: Jodi

Pepper I have to had very lack of appetite. Yesterday was my high carb day and I took in 1/2 of what I ate pre-Leptigen. I also have the slight abdominal discomfort. I do however feel bloated but its managable so far. Also I've notice regular bowel movements when I'm normally not regular due to IBS.

Since I've been taking Leptigen, my last few workouts have been kick ass and made a few personal gains.



Posted by: dg806

Quote:
Originally posted by Jodi
not regular due to IBS.
IBS??? Just curious, not trying to be nosey!



Posted by: Jodi

Your going to make me say it.

irritable bowel syndrome



Posted by: dg806

Sorry!



Posted by: gopro

TP, does this HAVE to be taken with water, or can it be mixed with anything else? Can it be mixed with anything containing protein, or does it have to be a non-caloric beverage?



Posted by: freeman1504

....appetite supression?!?! but I LOVE eating!!!!




Posted by: Tkarrde

Quote:
Originally posted by gopro
TP, does this HAVE to be taken with water, or can it be mixed with anything else? Can it be mixed with anything containing protein, or does it have to be a non-caloric beverage?
You could certainly mix this with a protein drink of some type, if you wished.



Posted by: gopro

Quote:
Originally posted by Tkarrde
You could certainly mix this with a protein drink of some type, if you wished.
Thanks Tkarrde



Posted by: Twin Peak

I often mix it with the Nectars, or with Xtreme's ICE.

When I want a low calorie version, crystal light works best.

Stay away from diet soda (its bad).

We are testing flavors now, and the retail version will be flavored.



Posted by: gopro

Quote:
Originally posted by Twin Peak
I often mix it with the Nectars, or with Xtreme's ICE.

When I want a low calorie version, crystal light works best.

Stay away from diet soda (its bad).

We are testing flavors now, and the retail version will be flavored.

Thanks for the info.



Posted by: Twin Peak

GP, are you, or do you plan on, using it?



Posted by: CaptainDeadlift

How long does it usually take to ship it?



Posted by: Twin Peak

It usually ships within a day or two, depending on backorders.



Posted by: gopro

Quote:
Originally posted by Twin Peak
GP, are you, or do you plan on, using it?
Perhaps in the future, but right now I have a client about to use it.



Posted by: DaMayor

Re: Flavoring........In addition to my previous choices of orange and/or lemon, I would like to add Orange Cream. I'm thinking this would blend well with the acidity and mask that funky assed smell/taste.....whatever it is.



Posted by: Twin Peak

We are testing tropical punch, lemonade, and lime. We'll pick the best one for our first round of retail product to be ready in September.



Posted by: Jodi

I think lemon or lime would hide the taste very well.



Posted by: DaMayor

Maybe a nice Bourbon flavor...Whiskey Sour? Nah, screwdriver, definately screwdriver. Make mine a double.



Posted by: OceanDude

Well I just ordered ab-solved and the lipoderm-y to give it a try. Where can you get Leptigen - no one seems to have it.



Posted by: Twin Peak

LG is not yet available retail (will be in a month or so). Its only available at avantlabs.com -- unflavored.



Posted by: katie64

Quote:
Originally posted by Twin Peak
Leptigen is now available for sale:

Earlier this week, the shipping of Avant Labs LeptiGen II, the long-awaited Cellular Metabolic Optimizer, has finally begun. For those of you who are unfamiliar, LeptiGen II is designed to deceive one’s body into thinking it is being fed without necessitating the calories traditionally required to elicit the hormonal response typified by the fed state. The dieter can now bypass the detrimental effects of the starvation response—metabolic downregulation and a in plateau fat loss, increased loss of Lean Body Mass, surge in appetite, fatigue, etc.—without the implementation of frequent, and often progress-hindering, refeeds. While other supplements offer only to camouflage the secondary effects of dieting, LeptiGen II prevents the actual genesis of these obstacles through the manipulation of their hormonal source, before they can become a hindrance to the realization of one’s goals.

For those interested in more information regarding this revolutionary product, there is a live chat tomorrow, July 24th, with the creator, Par Deus. For information regarding this chat, please refer to the thread on the Avant Forum. Please Note: Only registered board members may participate in this chat. We invite everyone to sign up today and pose your questions to the supplement designer.

As well, you might be interested in following DaMayor's journal where he will be tracking his dieting progress while using it.
Congratulations TP, Par Deus, Tkarrade and all of you, great work

Good Luck DaMayor...........



Posted by: DaMayor

Quote:
Originally posted by katie64
Congratulations TP, Par Deus, Tkarrade and all of you, great work

Good Luck DaMayor...........
Luck? This is Science, woman!


Thanks Dear.



Posted by: freeman1504

...AND hard work, don't forget that my man!



Posted by: DaMayor

I won't.



Posted by: Par Deus

Quote:
Originally posted by freeman1504
...AND hard work, don't forget that my man!
Indeed, I worked very hard to design LeptiGen



Posted by: freeman1504





Posted by: DaMayor

Oh, you were talkin' to Par!

Silly me.





Posted by: freeman1504

No, DM, I was talking to you!!!



Posted by: Jenny

I am very impressed by Avant's service and commitment! Ordered my Lipoderm and Leptigen in the end of last week and got my Lipo today! And I live in friggin' SWEDEN!

Thank's Avant ppl!



Posted by: Tkarrde

Quote:
Originally posted by Jenny
I am very impressed by Avant's service and commitment! Ordered my Lipoderm and Leptigen in the end of last week and got my Lipo today! And I live in friggin' SWEDEN!

Thank's Avant ppl!
Keep us posted on how the LeptiGen works for you



Posted by: Jenny

Quote:
Originally posted by Tkarrde
Keep us posted on how the LeptiGen works for you
Oh I will!



Posted by: nikegurl

very good news! i ordered mine late last week so maybe it'll get here by the end of this week. can't wait to get started.

no sure if i told you before jenny but your abs are looking good!



Posted by: Jenny

I don't have my Leptigen yet, the products were shipped separetly, custom reasons I think.

Thanks Nike!




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