Pages: 1
Aktibol???
(CLICK HERE here to view the original thread with full colors/images)
Posted by: Blumpkin
Aktibol (cobamide B12) 1000 mcg caps (same as Maxibol)
anyone ever heard of these? I need to know if this is a steroid or one of those "Gray market" supps
Posted by: Mudge
Injectable Vitamin B12.
Vitamin B12 is a water-soluble nutritional supplement.
Chemical Formula: C63H88CoN14O14P
Other names: Beta-cyano-(5',6'-dimethylbenzimidazolyl)-cobamide
Explanation: Vitamin B12 (cyanocobalamin) has many uses as a nutritional supplement in both humans and livestock. It is used in humans to treat pernicious anemia, hepatitis, cirrhosis of the liver, and to help maintain the body s metabolism. In its long-effect form (hydroxocobalamin), vitamin B12 is used to treat anemia, growth impediment, improvement in the function of the heart, liver, kidneys and nerves, and general strengthening of the body. In livestock, it is used to improve feed production.
Keywords: Cyanocobalamin, Hydroxocobalamin, antianemic, nutritional supplement
---
New function of vitamin B12: cobamide-dependent reduction of epoxyqueuosine to queuosine in tRNAs of Escherichia coli and Salmonella typhimurium.
Frey B, McCloskey J, Kersten W, Kersten H.
Institut fur Biochemie, Universitat Erlangen-Nurnberg, Federal Republic of Germany.
Queuosine (Q), 7-[(4,5-cis-dihydroxy-2-cyclopentene-1-yl)-amino)methyl)-7- deazaguanosine, and Q derivatives usually replace guanosine in the anticodon of tRNAs(GUN) of eubacteria and of cytoplasmic and mitochondrial tRNAs of lower and higher eucaryotes except yeasts. Q appears to be synthesized de novo exclusively in eubacteria, and the free-base queuine serves as a nutrient factor for eucaryotes. Recently, a Q derivative, oQ, containing a 2,3-epoxy-4,5-dihydroxycyclopentane ring, has been identified in Escherichia coli tRNA(Tyr). Here we show that oQ is formed when E. coli or Salmonella typhimurium is grown in glucose-salt medium. The formation of oQ was independent of molecular oxygen, and oQ-tRNAs were converted to Q-tRNAs by adding cobalamin to the growth medium. Under strictly anaerobic conditions, considerable amounts of Q were present in E. coli and S. typhimurium tRNAs when the bacteria were grown in the presence of cobalt ions with glycerol as the carbon source and fumarate as the electron acceptor. Under these conditions, the biosynthesis of cobalamin was induced. The results suggest that oQ is derived from ribose and that oQ is finally reduced to Q by a cobamide-dependent enzyme.
PMID: 3129401 [PubMed - indexed for MEDLINE]
(CLICK HERE here to view the original thread with full colors/images)
Aktibol???
Article Archives
