If you have acne and you want it to go away while your on a cycle, do not take tetracyclines. Tetracycline and anabolic steroids do not go well together. Tetracycline is a broad spectrum antibiotic that has many purposes. It works primarily by inhibiting protein synthesis. Since Tetracycline does exhibit this anti-anabolic effect, it is working in the opposite direction of the anabolic steroids. Anabolic steroids increase protein synthesis and can encourage bacteria growth which often aggravates acne. Tetracycline may inhibit the functions of the anabolic steroids, or the anabolic steroids may inhibit the effects of the Tetracycline. Rather than try to examine which drug would come out on top, it seems the easiest solution is to not use Tetracycline while taking anabolic steroids. Other ways that you can be able to control acne that is caused by the use of steroids include: showering more frequently, using prescription soaps, using tanning beds, by using Retin-A and the last course might involve using Accutane.