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Is Intermittent Fasting The Cure For Aging Brains?



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Old 06-17-2009, 01:29 PM   #1
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Is Intermittent Fasting The Cure For Aging Brains?



This study may be of interest to those who are beyond the half century mark.
Ageing Res Rev. 2006 Aug;5(3):332-53. Epub 2006 Aug 8.Click here to read Links
Caloric restriction and intermittent fasting: two potential diets for successful brain aging.
Martin B, Mattson MP, Maudsley S.
Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA. martinbro@grc.nia.nih.gov
The vulnerability of the nervous system to advancing age is all too often manifest in neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases. In this review article we describe evidence suggesting that two dietary interventions, caloric restriction (CR) and intermittent fasting (IF), can prolong the health-span of the nervous system by impinging upon fundamental metabolic and cellular signaling pathways that regulate life-span. CR and IF affect energy and oxygen radical metabolism, and cellular stress response systems, in ways that protect neurons against genetic and environmental factors to which they would otherwise succumb during aging. There are multiple interactive pathways and molecular mechanisms by which CR and IF benefit neurons including those involving ’slin’slin’slin’slin’slin’slin’slin-like signaling, FoxO transcription factors, sirtuins and peroxisome proliferator-activated receptors. These pathways stimulate the production of protein chaperones, neurotrophic factors and antioxidant enzymes, all of which help cells cope with stress and resist disease. A better understanding of the impact of CR and IF on the aging nervous system will likely lead to novel approaches for preventing and treating neurodegenerative disorders.

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Old 06-18-2009, 04:02 PM   #2
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How about keeping the brain active instead of watching so much TV as many people do. How about a good diet, which most people do not have.



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Old 06-18-2009, 05:27 PM   #3
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Wow, they needed a study to figure that shit out?



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Old 06-19-2009, 12:36 AM   #4
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Hay, Don't shoot me! I am just the messenger.



QUIET IS MIGHT. SOLITUDE IS STRENGTH. INTROVERSION IS POWER.
Words of a Wise Woman - We don't all get to have all things. I have been given more than most, not as much as others.
I enjoy the gifts that I have, I share what I can, and try not to begrudge others for having things that I don't have.
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Power House became my hospital and the iron became my medicine.
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Old 06-19-2009, 05:07 AM   #5
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No shooting of messengers here.



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Old 06-19-2009, 10:15 AM   #6
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I heard a couple years ago that fasting extends your life. I never understood it.. starve yourself and live a little while longer. I'd rather eat & and enjoy myself.. I'm pretty sure I'm going to die one day.
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Old 06-19-2009, 10:30 AM   #7
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We all are....anyways.


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I .. I'm pretty sure I'm going to die one day.



QUIET IS MIGHT. SOLITUDE IS STRENGTH. INTROVERSION IS POWER.
Words of a Wise Woman - We don't all get to have all things. I have been given more than most, not as much as others.
I enjoy the gifts that I have, I share what I can, and try not to begrudge others for having things that I don't have.
Quote:
Originally Posted by KelJu View Post
Power House became my hospital and the iron became my medicine.
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Old 06-19-2009, 07:07 PM   #8
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Quote:
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I heard a couple years ago that fasting extends your life. I never understood it.. starve yourself and live a little while longer. I'd rather eat & and enjoy myself.. I'm pretty sure I'm going to die one day.
Lower caloric consumption. Rodents fed diets doubled in calories live almost exactly half as long, although in humans I'm sure the correlation is more complex (especially since we don't eat standardized pellet food).

A scientist working off of this approach I think is consuming 1300 calories a day, weighs around 137 pounds? At that weight and being bald he looks pretty terrible though, someone may remember this guy.



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