I was in Peru recently, and every dollar changed was heavily scrutinized.
In neighboring Ecuador entire towns with many banks that were big banks refused to take 100s.
Ecuador uses the US Dollar by the way, which was a pain in the arse and made prices more expensive.
Now, it's the greenback. The Sacajewia coin is widely used for 1 dollars and there are nickels and dimes.
This has caused prices to creep up.
The current President, Rafeal Correa says making the switch was a mistake because it prevents monetary policy, etc. But there are no plans to dump the USD.
Peru was cheaper than Ecuador. Not a lot cheaper but cheaper enough to notice. Bolivia was more affordable than Peru. Bogota was cool.
If I didn't like to chat in bars with cervezas at night I would have spend $25 per day total which = $750 per month.