Molecular Condom to Fight HIV

**goandykid** · 12-30-2006, 11:37 PM

http://news.bbc.co.uk/2/hi/health/6216197.stm

Last Updated: Sunday, 31 December 2006, 00:21 GMT
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'Molecular condom' to combat HIV
Dr Patrick Kiser
Dr Kiser hopes the gel will be long-lasting
A "molecular condom" to protect women against HIV is being developed by US scientists.

The liquid formulated by a University of Utah team turns into a gel-like coating when inserted into the vagina.

Then, when exposed to semen, it returns to liquid form and releases an anti-viral drug to attack HIV.

However, the technology, featured in the Journal of Pharmaceutical Sciences, is still around five years away from being tested in humans.

We're shooting for a microbicide delivery system that would be used once a day or once a month
Dr Patrick Kiser
University of Utah

And the researchers predict it will be around 10 years before it might be in widespread use.

Researcher Dr Patrick Kiser said: "The ultimate hope for this technology is to protect women and their unborn or nursing children from the Aids virus."

The Utah project is part of a worldwide research effort to develop "microbicides" - drug-delivery systems such as gels, rings, sponges or creams to prevent infection by HIV and other sexually transmitted diseases.

They are seen as a way for women to gain power by protecting themselves from HIV, particularly in impoverished nations where Aids is widespread, where rape is rampant, or, where conventional condoms are taboo, not reliably available or where men resist using them.

Short-term effect

First-generation microbicides now being tested are expected to be available within four years and to be 50-60% effective.

However, Dr Kiser said they lasted only for a short time, meaning they had to be used shortly before sex.

The potential advantage of his technology is that it would be much longer lasting.

Microbicides could put the power of preventing HIV into women's hands
Yusef Azad
National Aids Trust

"We're shooting for a microbicide delivery system that would be used once a day or once a month," he said.

Tests have already shown that their 'hydrogel' is unlikely to cause significant side effects, or discomfort.

It is designed not to dehydrate vaginal cells, which can trigger infections, and not to be diluted by other fluids.

The next stage will be to see whether anti-viral drugs incorporated into the hydrogel can be released with the same efficiency as in the lab.

Indeed the researchers are hopeful that because the gel would be much thinner inside a woman than it was in the lab tests, the release of drugs should be even more effective.

High hopes

Yusef Azad, of the National Aids Trust, said: "Millions of women currently have little control over their sexual health and microbicides could put the power of preventing HIV into women's hands.

"It is vitally important that sufficient funding is channelled into the development of effective microbicides so that women have a range of options of products such as gels, liquids and creams that could provide a barrier to contracting HIV during sex."

Roger Pebody, treatment specialist for the HIV charity Terrence Higgins Trust said microbicides were one of the biggest hopes for preventing new HIV infections in the near future.

He said: "This is one of many projects that are in the early stages of development, however other microbicides could be as little as five years away."

**fufu** · 12-31-2006, 12:17 AM

So are they going to be shipping this stuff to Africa?

**goandykid** · 12-31-2006, 12:42 AM

10 years before its in widespread use, but I hope so.

**DOMS** · 12-31-2006, 08:29 AM

Africans don't use condoms.

Besides, when the girl that's being raped is age 11 and under, there's really no need to worry about her getting pregnant.

**P-funk** · 12-31-2006, 08:35 AM

Originally Posted by DOMS

Africans don't use condoms.

Besides, when the girl that's being raped is age 11 and under, there's really no need to worry about her getting pregnant.

holy shit! that is so fucked up. Why do they actually think that would work....what a bunch of dumb mother fuckers.

**DOMS** · 12-31-2006, 08:37 AM

Originally Posted by P-funk

holy shit! that is so fucked up. Why do they actually think that would work....what a bunch of dumb mother fuckers.

My thoughts exactly.

"According to the latest report by South Africa's Police Service, children are the victims of 41 percent of all rapes and attempted rapes reported in the country. Over 15 percent of all reported rapes are against children under 11, and another 26 percent against children 12-17. For the year 2000, some 58 children were raped or the victims of rape attempts in South Africa every single day."

And these figures are out of date. It's gotten worse since 2000.

**P-funk** · 12-31-2006, 08:38 AM

Originally Posted by DOMS

My thoughts exactly.

"According to the latest report by South Africa's Police Service, children are the victims of 41 percent of all rapes and attempted rapes reported in the country. Over 15 percent of all reported rapes are against children under 11, and another 26 percent against children 12-17. For the year 2000, some 58 children were raped or the victims of rape attempts in South Africa every single day."

what a bunch of animals. Those people are pathetic.

**DOMS** · 12-31-2006, 08:57 AM

It gets better:

"Child and adult rape survivors interviewed by AI in August, all of whom were HIV positive, had access to emergency medical care. However, they had considerable difficulties in obtaining further medical treatment or psychological care because of the social stigma, unemployment, and their lack of secure housing and access to affordable transport. In one case the survivor and her mother were threatened with violence by the perpetrators, who had been released on bail."

So, every woman/child that has been raped has been given a death sentence.

**P-funk** · 12-31-2006, 09:03 AM

what is wrong with the people in that part of the world? What a bunch of fucking animals.

**joesmooth20** · 12-31-2006, 10:29 AM

Africa is a lost cause and it will never get better.

**BoneCrusher** · 12-31-2006, 10:45 AM

Wonder it is a lost cause over there?

**DOMS** · 12-31-2006, 10:47 AM

Originally Posted by BoneCrusher

Wonder it is a lost cause over there?

You seem to have forgotten to include a word or two.

**DOMS** · 12-31-2006, 10:48 AM

Originally Posted by joesmooth20

Africa is a lost cause and it will never get better.

**BoneCrusher** · 12-31-2006, 11:03 AM

Originally Posted by DOMS

You seem to have forgotten to include a word or two.

Wonder why it is a lost cause over there?

Okay ya got me ...

... repaired and reposted.

**DOMS** · 12-31-2006, 01:54 PM

Originally Posted by BoneCrusher

Wonder why it is a lost cause over there?

Because of their shitty culture.

Originally Posted by BoneCrusher

Okay ya got me ...

... repaired and reposted.

I wasn't picking on you, I just wanted to know what you meant.

**Little Wing** · 12-31-2006, 03:14 PM

like i said before, places in the world where children are born to and raised by people with shit for brains need to be brought into the light. one way or another. i'm all for a red, white and blue planet if it will help stem this shit. plenty of shit to stop the flow of right here too... step one should be getting rid of most of the people in our prisons overnight.

**DOMS** · 12-31-2006, 03:29 PM

Originally Posted by Little Wing

like i said before, places in the world where children are born to and raised by people with shit for brains need to be brought into the light. one way or another. i'm all for a red, white and blue planet if it will help stem this shit. plenty of shit to stop the flow of right here too... step one should be getting rid of most of the people in our prisons overnight.

I think I love you.

**Little Wing** · 12-31-2006, 04:06 PM

too bad some politician doesn't at least suggest it. no one has enough balls or common sense to clean this mess up.

**Witmaster** · 12-31-2006, 04:17 PM

I'm encouraged by this new technology. Although Africa does have a rampant problem with HIV/Aids it's important to remember that we do have an increasing problem here Stateside. Of course, this technology only works if people are willing to use it.

I'd still give anything to have 5 minutes alone with the sadistic motherfucking bastard who infected my friend.

**DOMS** · 12-31-2006, 04:45 PM

Originally Posted by Witmaster

I'm encouraged by this new technology. Although Africa does have a rampant problem with HIV/Aids it's important to remember that we do have an increasing problem here Stateside. Of course, this technology only works if people are willing to use it.

Not so.

"The rate of decrease in AIDS diagnoses slowed in the late 1990s. After reaching a plateau, the estimated number of diagnoses increased slightly each year from 2001 to 2005, reaching 45,669 in the last year. In total, an estimated 988,376 people have been diagnosed with AIDS."

And this is more impressive when you consider the mongrels coming up with from Mexico that do horrible things to all of our statistics.

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