Thread: Igf-LR3 vs igf DES

DES is about 1000x more potent. Something to do with they remove the last 3 Amino's on the chain to make the 'key' fit that many more receptors??

LR3 much longer half/life - so great in the AM

DES is still fairly new, not much out there about it. - Great Post workout, or pre-workout depending on what research you follow

I'm currently about 4 days deep into DES use.


If I'm wrong at all here, I hope I get corrected.

There is so much info out there sometimes you buy into bad info as true. I've been researching this alot lately myself.

I feel great on the DES however.

What's the pinning protocol with DES? I know lr3 is immediate post workout, like3-5 minutes max


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Same.

If stacking the 2 the DES should be Post workout and LR3 can be a morning job...

I think DES (being so many times more potent) sounds most beneficial post workout to aid in recovery.

There is also speculation that it may cause muscle hyperplasia (cell division) down the road. Which means MORE muscle, not just bigger muscles. Time frame for this I have no idea.

Once again, I don't want to get slammed if I'm wrong I'm just trying to get my facts straight too. Not many seem to know much about it, so I want to share what I have researched.

iam using the des version right now pre workout bilat in muscles worked that day and getting sick ass pumps feel stronger and i feel like iam recovering faster in between sets i have been doing this for about 3 weeks now and definitely see a decrease in bf and a increase in vascularity and also on a side note i started the des when i was coming of blast and going back to cruising

from what everyone tells me, i'm using igf for about 6 weeks and then i start des for a few weeks

If DES is more potent and it's cheaper, why the he'll bother using L3?

Good question^^^^

Originally Posted by Chino0823

Good question^^^^

Just been bothering me for sometime now.

Can we get some input Twist?

Now I'm confused.

Is DES a potency form of IGF-LR3, or is it's halflife closer to that of straight IGF-1 which is a VERY VERY SHORT half life??

I've heard shorter half life, 8 hours I believe but don't quote me. You just inject into your muscles post workout. I've heard because of the shorter half life it can't float around and go to unintended places, so that would make it safer?

Originally Posted by Thresh

I've heard shorter half life, 8 hours I believe but don't quote me. You just inject into your muscles post workout. I've heard because of the shorter half life it can't float around and go to unintended places, so that would make it safer?

No, IMO it means it's healing and growth properties are more isolated to the inj site.

I do like the idea of a longer 1/2 life so it does its healing magic all over.

I guess why there is research going on with stacking the both together.

DES has about 1/10th the half life of lr3, and has been altered to fit into receptors that have been misshapen by acidosis, making it more "potent" because it will bind with more receptors in selected tissue sample. Lr3 is normal IG3 that has a longer half-life and will remain systemically longer in test systems such as rats.

Remember, this is only in research and tissue samples, and use in humans is strictly prohibited and discouraged.

-T

I remember when IGF-1 first came on the scen. Or atleat my scen back in 2000. We were banging 20mcg every 2-3 hours, lol...
Made me sick as hell the first week. but worked great.