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Why we should all use Exemestane

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  1. 10-10-2011, 12:06 PM #1
    Livebig14
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    Why we should all use Exemestane

    Heres an article I found on another website guys.


    Aromasin (exemestane) is a steroid-al AI - an irreversible aromatase inhibitor ... great for controlling estrogen "during cycle" and "PCT" ...

    But, what else does it do ???
    Good reading....

    ABSTRACT FROM JOURNAL OF CLINICAL ENDOCRONOLOGY AND METABOLISM

    Suppression of estrogen, via estrogen receptor or aromatase blockade, is being investigated in the treatment of different conditions. Exemestane (Aromasin) is a potent and selective irreversible aromatase inhibitor. To characterize its suppression of estrogen and its pharmacokinetic (PK) properties in males, healthy eugonadal subjects were recruited. In a cross-over study, 12 were randomly assigned to 25 and 50 mg exemestane daily, orally, for 10 d with a 14-d washout period. Blood was withdrawn before and 24 h after the last dose of each treatment period. A PK study was performed (n = 10) using a 25-mg dose.

    RESULTS :

    The 25- and 50-mg doses of daily exemestane had comparable effects in suppressing circulating estrogen concentrations, with 38 ± 24% (mean ± SD; P = 0.002 vs. baseline) and 32 ± 29% (P = 0.008) decreases in estradiol concentrations, 71 ± 12% (P < 0.0001) and 74 ± 12% (P < 0.0001) decreases in estrone concentrations, and 45 ± 27% (P = 0.004) and 51 ± 20% (P = 0.02)

    BUT THERE'S MORE

    There was an increase in circulating testosterone concentrations after both 25 mg (60 ± 58%; P = 0.001) and 50 mg (56 ± 48%; P = 0.003) exemestane. Androstenedione concentrations were increased as well after 25 mg (32 ± 36%; P = 0.004) and 50 mg (47 ± 59%; P = 0.052) exemestane, respectively (Fig. 1Go and Table 2Go).

    SHBG concentrations were decreased by 21 ± 7% (P = 0.0003) and 19 ± 39% (P = 0.18) at 25 and 50 mg exemestane, respectively.

    Free testosterone concentrations were increased by 117 ± 74% (P = 0.0001) and 154 ± 95% (P < 0.0001) at both doses, due to the decrease in SHBG and the increase in total testosterone.

    THE ICING ON THE CAKE !

    There were no changes in circulating serum triglycerides, cholesterol, or LDL or HDL cholesterol concentrations with either dose of exemestane.
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  3. 10-10-2011, 09:06 PM #2
    dwmer
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    I've always used arimidex. Is aromasin really better?
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  4. 10-10-2011, 09:36 PM #3
    ScottyMac710
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    Good post, have always gone with aromasin over adex - better overall, less chance of rebound, less sides, obvious choice overall IMO
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  5. 10-10-2011, 09:36 PM #4
    SFW
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    My Sponsored Kalpa Journal, courtesy of Neomeds.com
    http://www.ironmagazineforums.com/ne...taxyl-log.html



    hhttp://www.NeoMeds.com
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  6. 10-10-2011, 10:40 PM #5
    Vibrant
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    Quote Originally Posted by SFW View Post
    Looks like you need a cup of



    http://www.labpe.com/?referrer=CNWR_2221329406037
    Please use my coupon code: IMVibrant The more you use it the bigger the discount for you
    Planning a peptide order? talk to me and I may be able to get you some extras
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  7. 10-11-2011, 08:11 AM #6
    tballz
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    I prefer aromasin.
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  8. 10-11-2011, 12:18 PM #7
    ScottyMac710
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    Quote Originally Posted by tballz View Post
    I prefer aromasin.
    exemestane = aromasin
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  9. 10-11-2011, 12:34 PM #8
    Ahrnold
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    fo shizzle
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  10. 10-11-2011, 12:39 PM #9
    tballz
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    Quote Originally Posted by ScottyMac710 View Post
    exemestane = aromasin
    Yea...I know.
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  11. 10-14-2011, 08:21 PM #10
    coolrise
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    Adex on and aromasin after.
    Anything I post on this board is based on Fantasy and Science Fiction...and stuff I may or may not have read somewhere else...
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  12. 10-14-2011, 11:32 PM #11
    wisco
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    I used aromasin this time around (with clomid) I will never use anything else. I feel like I recovered so perfectly, it definitely did its job
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  13. 10-17-2011, 09:18 AM #12
    testosteronebaby
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    i like this stuff it's very good
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  14. 10-23-2011, 09:51 AM #13
    PappyMason
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    good info
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  15. 10-23-2011, 02:22 PM #14
    ldyzluvdis06
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    awesome, makes me glad i just ordered some!
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  16. 10-23-2011, 04:27 PM #15
    Wooll
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    Appreciate the info.
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  17. 10-23-2011, 05:25 PM #16
    8thangel
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    After doing a hood bit if studying on it I have only used Aromasin for my AI exclusively and have had excellent results with it.

    I'm on on doctor rx'd trt anyhow and had higher levels of e2 even at trt doses of test. After going round and round with my doc about rx'ing me an AI for it (and him saying no) I finally procured some from a source and have since had perfect e2 levels for my last two lab draws.

    I finished a 16 week blast recently and thought maybe my e2 was gonna be author high as a result but it was perfect, 25. My total test was pretty high considering I dropped my dose significantly in an effort to get back to an acceptable level so my doc wouldn't freak out. Additionally my free test was actually very high, which thankfully the doc didn't care about but it seems to go with what was states in the study above as previously it was just in the normal range.

    Anyhow, Aromasin is the only way I will fly from now on!
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  18. 11-10-2011, 03:31 PM #17
    jojojojo
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    Quote Originally Posted by 8thangel View Post
    After doing a hood bit if studying on it I have only used Aromasin for my AI exclusively and have had excellent results with it.

    I'm on on doctor rx'd trt anyhow and had higher levels of e2 even at trt doses of test. After going round and round with my doc about rx'ing me an AI for it (and him saying no) I finally procured some from a source and have since had perfect e2 levels for my last two lab draws.

    I finished a 16 week blast recently and thought maybe my e2 was gonna be author high as a result but it was perfect, 25. My total test was pretty high considering I dropped my dose significantly in an effort to get back to an acceptable level so my doc wouldn't freak out. Additionally my free test was actually very high, which thankfully the doc didn't care about but it seems to go with what was states in the study above as previously it was just in the normal range.

    Anyhow, Aromasin is the only way I will fly from now on!
    i am kinda doing the same thing but with .5mill letro twice a week my doc has me on axiron and is working out pretty well but was thinking about going to aromasin...afraid of using letro long term
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  19. 11-11-2011, 04:33 PM #18
    TJTJ
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    When will you have exemestane back in stock?
    It doesn't matter how you find the pot of gold, so long as you beat the leprechauns.
    TJTJ is fictional character and purely theoretical.
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  20. 11-15-2011, 01:11 PM #19
    Ahrnold
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    aromasin, first time user here...killed my libido, dont even think about s*x...Im tapering to 300mg test C per week now maybe I can just stop taking it and just do my usual pct with nolva and clomid?
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  21. 11-15-2011, 01:30 PM #20
    TJTJ
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    Quote Originally Posted by Ahrnold View Post
    aromasin, first time user here...killed my libido, dont even think about s*x...Im tapering to 300mg test C per week now maybe I can just stop taking it and just do my usual pct with nolva and clomid?

    What was your dosage of the aromasin? ED or EOD? When did you start it and for how long? IMO it could be the Test youre running killing your libido. How long have you been running test?
    It doesn't matter how you find the pot of gold, so long as you beat the leprechauns.
    TJTJ is fictional character and purely theoretical.
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  22. 11-15-2011, 01:37 PM #21
    Ahrnold
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    around 10 weeks, no higher than 500mg per week, did aromasin eod to start out and now doin ed
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  23. 11-15-2011, 01:45 PM #22
    TJTJ
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    Quote Originally Posted by Ahrnold View Post
    around 10 weeks, no higher than 500mg per week, did aromasin eod to start out and now doin ed
    what is the dosage of the aromasin?
    It doesn't matter how you find the pot of gold, so long as you beat the leprechauns.
    TJTJ is fictional character and purely theoretical.
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  24. 11-16-2011, 08:07 AM #23
    Ahrnold
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    25mg
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  25. 11-16-2011, 01:43 PM #24
    TJTJ
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    Quote Originally Posted by Ahrnold View Post
    25mg

    Try it at 25/25/12.5/12.5mgs ed
    It doesn't matter how you find the pot of gold, so long as you beat the leprechauns.
    TJTJ is fictional character and purely theoretical.
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