Thread: Melanotan II Q&A

What is Melanotan II?

Melanotan II is a cosmetic product that stimulates a natural increase in melanin production. Melanin is the main determinant of skin color in humans, a brown pigment which causes skin to become darker in appearance, instead of red, when exposed to UV rays. Users of Melanotan II develop a gradual, natural looking tan with minimal sun exposure. It is particularly useful for fair-skinned individuals who find that they cannot tan simply by spending time in the sun; however, excellent cosmetic tanning results are achieved by all skin types.
What Melanotan II is not

Melanotan II is not a treatment or cure for any disease, nor should it be used with the aim of preventing skin cancer. While melanin is known to have excellent photo protectant properties, no clinical studies have ever indicated the efficiency of Melanotan II specifically in reducing UV damage, therefore the product should not be used solely as a replacement for sunscreen or other appropriate UV protection.


I am very fair skinned; will Melanotan II work for me?

Melanotan II works for very well for all skin types and you can expect your tan to darken several shades regardless of how fair your skin is to begin with. Those with very pale skin have the most to gain from Melanotan II usage and usually end up seeing the most significant degree of change in their tan compared to those who have darker skin to begin with.

How many vials should I purchase to start with and when will I see results?


Generally most people will see excellent results by the end of 20mg (2 vials) of Melanotan II, although some see results from as little as 5-10mg - which equates to being as quick as 7-10 days of beginning their injections. Those with extremely fair skin will need more Melanotan II to see initial results and most likely won’t see optimal results until 4-5 weeks of usage. The average time for great tanning results is 2-3 weeks assuming Melanotan II is combined with a sufficient amount of UV exposure.
Doses are weight dependant so those who weigh less (particularly women) can get away with purchasing less than those who are heavier. Your first Melanotan II vial will usually only last 2-3 weeks as daily injections are required. For maintenance (i.e. once you have a tan you are happy with), vials should last longer at 4-8 weeks depending on your dose.


What is the difference between Melanotan I & Melanotan II?


Although they both stimulate the release of melanin, their purposes and mode of action are vastly different. Melanotan I (Afamelanotide) is being clinically trialed for its therapeutic benefits in the treatment of rare skin conditions. It is not used to cosmetic purposes as a dose of 6-8 times more would be needed to achieve similar tanning results to Melanotan II – a product used solely to assist cosmetic skin tanning results.
Comparing these two products would be similar to comparing a prescription stimulant medication such as Ritalin to a Red Bull drink. Both work as stimulants, but the prescription stimulant is used to treat medical conditions such as ADHD while Red Bull is a product used simply to assist in boosting energy.


How much Melanotan II do I need to take each time?

The dosing guideline for Melanotan II is 1mg per 100kg of bodyweight. Generally for females this equates to around 0.5-0.65mg of Melanotan II per injection (meaning 15-20 doses per vial) and for males 0.65mg-1mg per injection (10-15 doses per vial).

How often do I need to take Melanotan II?

It is recommended to take your Melanotan II dose each day initially and go tanning 1-2 times a week if you wish to see results quickly (within 2-3 weeks). When you're happy with your color you can cut back to injecting your dose to every 2nd or 3rd day and go tanning just once per week for maintenance. Basically the darker your skin becomes the less Melanotan II and UV rays you will need to maintain the tan.

Why do I still need to get UV exposure on Melanotan II?


Clinical data indicates the tanning efficiency of Melanotan II without the need to combine it with any UV exposure, but results can achieved much faster, and usually with a nicer overall color, when you also incorporate 1-2 short tanning sessions per week with your Melanotan II usage.
The reason for this is that while Melanotan II does significantly raise levels of melanin in the body, UV rays play an important factor in the secretion of the your body’s melanin in to surrounding skin tissue – melanin is of course being the brown pigment responsible for giving your skin its tanned appearance.


How much water should I mix into the vial?

The amount of water you use makes no difference, it just means you will have 10mg of Melanotan II diluted in however much water you have used. For ease of dosing we recommend using just 1ml (100 units) of water. Therefore every 0.1ml (10 units) will be 1mg of Melanotan II. 0.05ml (5 units) will be 0.5mg of Melanotan II etc.

How do I store Melanotan II?

The manufacturer instructs that both mixed and unmixed vials of Melanotan II should be stored at refrigerator temperature at 2-8 degrees celcius. At this temperature mixed vials should be used within 2 months, while vials in powder form will remain stable for up to 1 year. To ensure no cross-contamination vials should always be stored away from food in an enclosed plastic satchel or container.

Are there any initial side effects?


For most users who take the appropriate dosage Melanotan II does not present any adverse side effects. Of those who do experience side effects they are generally those documented in the original clinical study of Melanotan II in humans, namely: flushing of the face, nausea and spontaneous erections in males. These side effects usually only last for 1-2 hours after the injection and usually only occur after the first 1-3 injections, after which they do not occur again unless a long break is taken between usage.
To reduce the occurrence of side effects its recommended to take your dose just before going to sleep at night and preferably having eaten 1-2 hours before (i.e. not on an empty stomach). If you are sensitive you should also take an anti-histamine 2 hours before injection.


Are there any long term side effects of Melanotan II?


While Melanotan II was developed by scientists in the 1980’s its usage in the general population is relatively new, with the earliest reports dating back to 2003. Unfortunately it’s impossible to know for certain the long term side effects of any product until it has been used by many individuals for a long period of time. Pleasingly though, reports and detailed logs from people using the product consistently for the past 5-6 years indicate that there are no documented long term side effects of Melanotan II usage.
This is not to say that we can guarantee the safety of Melanotan II, the information we present should not be mistaken as medical fact. As with any product (even licensed over the counter products) the safety and reaction of each individual cannot be 100% assured. So far though, no serious negative consequences have been reported by users. Furthermore, no hypothetical side effects or warnings reported in the media have been proven or substantiated with scientific fact – they are merely attempts not to get consumers to use an unlicensed product.

Originally Posted by Agentyes

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