Comparisons with methyltest, winny, anadrol and test prop showed better mytropic effect on the castrates with Dimethazine.
Biological activity of dimethazine in the protein-anabolic field.
Matscher, R.; Lupo, C.; De, P. Ruggieri. Lab. Ric. Ormonoter. Richter, Milan, Bollettino - Societa Italiana di Biologia Sperimentale (1962), 38 988-90. CODEN: BSIBAC ISSN: 0037-8771. Journal language unavailable. CAN 58:34623 AN 1963:34623 CAPLUS
Abstract
Dimethazine (I), 2,17-dimethyl-5-androstan-17-ol-3,3'-azine, was compared to methyltestosterone, oxymethalone, androstanazole and testosterone propionate in its protein-anabolic activity. The tests were made on castrated rats with a single hypodermic injection of 250 , on young male and female rats with increasing daily oral doses from 100 to 1000 for 30 days, and on adult male rats with daily oral doses of 1000 for 25 days. It was shown that I did not interfere with the growth of young animals; that adult rats treated with I gained, on an av., 20 g. more in wt. than the controls; and that I had a greater myotropic effect on castrates than the other steroids, and induced a higher N retention than methyltestosterone in adult males.






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