Thread: Strong natural anti-oestrogens in Brassaiopsis glomerulata

Strong natural anti-oestrogens in Brassaiopsis glomerulata

As designer supplements containing synthetic steroid compounds are being withdrawn from the market, more and more supplements with exotic extracts are being launched. One of these new extracts is Brassaiopsis glomerulata. A study by cancer researchers suggests that it blocks the enzyme aromatase.

Extracts of Brassaiopsis glomerulata are found in Triazole, an anti-oestrogen supplement/testosterone booster produced by Driven Sports. Brassaiopsis glomerulata is not the only ingredient in Triazole, but it is the one that the manufacturer trumpets about most in the publicity material. Other ingredients include extracts of Prunella vulgaris [common name self-heal, found along waysides], propolis and turmeric.

The manufacturer got 7 human guinea-pigs to use Triazole. According to the advertising claims the subjects' free testosterone levels went up by 146 percent and their estradiol level dropped by 45 percent.

Brassaiopsis glomerulata is a shrub found in the Far East, which local healers use to cure all sorts of complaints – from rheumatism to back pain to constipation. Healers in China use the plant to stimulate urine production.

Because little was known about the components of Brassaiopsis glomerulata, American cancer researchers subjected it to examination. They are searching for naturally occurring compounds that inhibit the conversion of androstenedione and testosterone into estradiol. Pharmacologists may be able to use compounds like this for new medicines against hormone-sensitive forms of cancer.

The researchers discovered that extracts of the leaves of Brassaiopsis glomerulata have an anti-oestrogenic effect. They isolated the ingredients in the extract and determined the anti-oestrogenic effect of each one. The researchers looked at whether the compounds were capable of inhibiting the aromatase enzyme that converts androstenedione into female hormones in test tubes [non-cellular], and whether they inhibited the conversion in live human cells [cellular].

The researchers tested the plant ingredients in a concentration of 20 micrograms per millilitre. They compared their anti-oestrogenic effect with that of cytadren [AG] [50 micrograms] and letrozole [20 nanomols].

Strong natural anti-oestrogens in Brassaiopsis glomerulata

IIRC this is an ingredient in DS's Triazole.... you guys going to add it to a formula or something? Triazole works well and I'd love to see what you guys can come up with using this and your other anti-e formulations!

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