Fast-aging mice live longer and stay on the ball on a diet with relatively large amounts of polyunsaturated fatty acids. Read: fish fatty acids.
SAMP8 mice age more quickly than ordinary mice. They live for 10-17 months. The letters SAMP stand for senescence-accelerated-prone mice. SAMP-8 mice are a favourite with Alzheimer's researchers because these lab animals quickly start to develop problems with gathering and retaining information. At a young age amyloid-beta peptides start to form in their brains. These are the building blocks of the plaques that are also found in the brains of human Alzheimer's patients.
Nutritionists at the Nara Women's University in Taiwan wanted to know whether playing with the fatty acid composition of the mice's diet would increase their lifespan and learning capacity. They divided their lab animals into 4 groups, and gave each group a slightly different diet for their entire lifespan.