Thread: More research on Toco-8

Originally Posted by Rodja

Check out this bitchin' study:

Vitamin E tocotrienols improve insulin sensitivity through activating peroxisome proliferator-activated receptors.

Abstract:
Vitamin E is comprised of two classes of compounds: tocopherols and tocotrienols. Tocotrienol-enriched palm oil has been shown to help reduce blood glucose levels in patients and preclinical animal models. However, the mechanistic basis for tocotrienol action is not well established. Peroxisome proliferator-activated receptors alpha, gamma, and delta (PPARalpha, PPARgamma, and PPARdelta) are ligand-regulated transcription factors that play essential roles in energy metabolism. Importantly, synthetic PPARalpha and PPARgamma ligands are currently used for treating hyperlipidemia and diabetes. In this study, we present data that tocotrienols within palm oil functioned as PPAR modulators. Specifically, both alpha- and gamma-tocotrienol activated PPARalpha, while delta-tocotrienol activated PPARalpha, PPARgamma, and PPARdelta in reporter-based assays. Tocotrienols enhanced the interaction between the purified ligand-binding domain of PPARalpha with the receptor-interacting motif of coactivator PPARgamma coactivator-1alpha. In addition, the tocotrienol-rich fraction of palm oil improved whole body glucose utilization and insulin sensitivity of diabetic Db/Db mice by selectively regulating PPAR target genes. These lines of evidence collectively suggested that PPARs represent a set of molecular targets of tocotrienols.PMID: 19866471

I swear, at least once a month I am reminded of why I take this supplement year round.

It's very pricey. . . For a placebo

Gotta love those placebos that have empirical evidence....

Originally Posted by theCaptn'

It's very pricey. . . For a placebo

A Vitamin product is placebo now?

Originally Posted by theCaptn'

It's very pricey. . . For a placebo

At 30 dollars for 2 months, it's twice as cheap as the next leading placebo!

lol...unreal

Nice post Rodja

Originally Posted by HereToStudy

I swear, at least once a month I am reminded of why I take this supplement year round.

Indeed. Toco 8 is actually getting a lot of love without us even mentioning it over at RX.

Originally Posted by theCaptn'

It's very pricey. . . For a placebo

this is the only placebo that works for me then!

bumpin' this up

yeah... def not a placebo.

Thanks for posting yet another study on toco

Besides the studies, Toco 8 has a solid reputation and its becoming more well known throughout the bb community.

Originally Posted by Good Grip

Besides the studies, Toco 8 has a solid reputation and its becoming more well known throughout the bb community.

I can understand why, helps with lipids, hair, skin, and a constant flow of additional support.

Originally Posted by |Z|

yeah... def not a placebo.

Thanks for posting yet another study on toco

I wouldn't go more than a week without toco-8 lol, it's kind of a sickness

Do you guys take vitamin C with your toco-8? I know vitamin E can deplete vitamin C.

Originally Posted by BigBlackGuy

Do you guys take vitamin C with your toco-8? I know vitamin E can deplete vitamin C.

I don't supplement with Vit C as it's so prevalent in every food that I eat.

Ahh got me some today on my rep order looking foward to this becomming a stapple. PP still making raves in their andro line now they need to stop teasing us and lets us now, as the "The Truth Will Set You Free" haha

Originally Posted by packers6211

Ahh got me some today on my rep order looking foward to this becomming a stapple. PP still making raves in their andro line now they need to stop teasing us and lets us now, as the "The Truth Will Set You Free" haha

In due time friend, in due time....

Originally Posted by Rodja

I don't supplement with Vit C as it's so prevalent in every food that I eat.

Its wise to supplement your vitamin C because it is readily excreted and cannot be stored in the body.

Originally Posted by TJTJ

Its wise to supplement your vitamin C because it is readily excreted and cannot be stored in the body.

Even if you get enough from food?

I use it post workout, that's about it

Originally Posted by TJTJ

Its wise to supplement your vitamin C because it is readily excreted and cannot be stored in the body.

Vit C is ubiquitous in produce, which I consume in vast quantities everyday (Paleo diet).

Originally Posted by ryansm

Even if you get enough from food?

I use it post workout, that's about it

I will use it post WO, but I do dose it heavy when I am getting sick, lol.

Originally Posted by TJTJ

Its wise to supplement your vitamin C because it is readily excreted and cannot be stored in the body.

Nice thank you for the advice.

Originally Posted by HereToStudy

I will use it post WO, but I do dose it heavy when I am getting sick, lol.

I notice Green Tea keeps me from getting sick

It's not a supplement, but I really think my consumption of blueberries and pineapple goes a long way to preventing illness.

Originally Posted by Rodja

It's not a supplement, but I really think my consumption of blueberries and pineapple goes a long way to preventing illness.

I try to be heavier with fruit consumption then I used to in general. Mostly berries though.

Originally Posted by HereToStudy

I try to be heavier with fruit consumption then I used to in general. Mostly berries though.

If berries were cheaper, I'd eat them exclusively.

I try to eat an apple a day but I really need to eat more fruits and veggis in my diet. Ive been looking more into anti-oxidants lately for cell health.

Originally Posted by Rodja

If berries were cheaper, I'd eat them exclusively.

I hear you on that.

Anyone using the toco for hair protection?