Thread: SYTENHANCE product testers wanted

For those of you not familiar with Dave and Xtreme, Xtreme is an excellent company who has products such as ICE and Vendetta (two I love).

Dave is also the owner of proteincustomizer, who many of you are familiar with.

Until I get the real write-up done, at the end of the week, here is some info on the general theory:

"Androgens exert much of their effects locally, at the cell level, be it in muscle, fat, the brain, liver, etc. They are taken up by the cells in those tissues, they bind to the AR in those cells, and subsequently activate transcription, thus protein synthesis, glycogen storage, etc., in those cells.

IOW, high androgen concentrations (and binding), in a cell in the muscle, does not activate transcription in the hypothalamus

That is pretty straightforward, but it tells us that if we could get high concentrations in one tissue over the other, we could achieve a stronger effect in that tissue over the other (all else being equal)

As to getting higher concentrations in one versus the other, that is all about delivery, and I would point to LipoDerm in support of that -- both the science I presented in my write-up (which showed much higher ratio of active in muscle compared to systemic vs. oral or another topical) as well as anecdotal evidence (people who can't take 10mg, orally, who can do 200mg/day dosing for weeks at a time (meaning it is not just a time-release thing, because levels would build-up).

The mechanism for local delivery is the same in both products, what differs is the additives for increasing total delivery, because of the different physical properties of the active (lipophillic vs. hydrophillic), which changes the rate limiting step for total flux (particularly in the real world, where one showers)

As to adipose vs. fat -- i.e. that they are different tissues, so the pharmacokinetics might be different (I assume this is your concern, as you did not specify) -- the main difference is blood flow, which means the active is more likely to be taken up, in the muscle, than the fat -- and this is reflected by lower concentrations in the muscle vs. adipose -- but, as mentioned, the ratio and total concentration in muscle vs. systemic, was still much higher than vs. oral or a different delivery vehicle.

Androgens are metabolized locally, in all of these same tissue I mentioned earlier -- both Phase I and Phase II metabolism takes place, thus by the time the steroids are taken up by the blood, and delivered systemic, most of it has been metabolised to inactive compounds, which would be excreted, thus it would not activate negative feedback in the hypothalamus and testes.

As a bit of an aside, androgen are also quite lipolytic in SubQ fat, so might see some localized fat loss as well."

u gotta be 21?no exceptions???

yes!

Originally posted by XtremeFormula
respected on this board

Damned...that sure narrows it down!! lol

Its a great chance you are offering though! Look forward to watching this.....

Hmmmmm? (DG has wheels turning - thinking)

I Pm'ed you Xtremeformula, are there any side effects?

Everyone interested, post info here.

I want to try it on my calves and side delts. These are the two areas that lag behind the rest of my physique. I am willing if Xtreme is.

Originally posted by BabsieGirl
Why does it have to be a male? Why not study both male and female? You'd think the study would involve more women, since it's harder for us to put muscle on.

Why the age of 21?

Sorry for ?'s. Just curious.

Because the active ingredients are androgens -- i.e. they are male hormones, or convert to male hormones.

Come on people, this stuff truly is excellent.

If you'll allow women to try, I'm game.

Originally posted by Twin Peak
Come on people, this stuff truly is excellent.

I already Pm'ed Xtreme, I am interested.

so what's the verdict, who's it going to be????????

Impatient.

Give Dave a chance, also, give the members a chance to volunteer.

Excuse me if this is common knowledge, but which androgen is present in the design?

Originally posted by Twin Peak
Impatient.

Give Dave a chance, also, give the members a chance to volunteer.

Well, there is me, and then one other person

Originally posted by The_Chicken_Daddy
Excuse me if this is common knowledge, but which androgen is present in the design?

Its a combo of 1-test and 4-diol. I don't know what the ratio is, or whether its a proprietary blend.

Gravy.

Cheers, Ste.

Who has Avant got testing Lipo ODB & ODC?

sorry if this is a stupid question, but does Super One+ have any effects on the application site?

Originally posted by The_Chicken_Daddy
Gravy.

Cheers, Ste.

Who has Avant got testing Lipo ODB & ODC?

We had a couple people test a formula that was a mix of the 2, on bb.com -- both lost over 1 inch on waist -- one guy was about 9% and the other was 6%, so we were pleased.

Not sure how much more testing we will do, as people have been waiting for Ultra for about 1.5 years, and regular Lipo is already very well established, so generating sales is not likely to be much of a problem.

BTW, I finished the write-up on Sytenhance, about 1 hour ago, so it should be up, somewhere, fairly soon.

Lipo Ultra/ODB write-up should be up, on our site, today, as well.

Originally posted by Prince
sorry if this is a stupid question, but does Super One+ have any effects on the application site?

You feel ignored Prince???

Replying to youre own questions...

yeah, it was a simple fricking question.

Im fairly new to the board, but I would be interested .....

jdpearce4@earthlink.net

Let me know

From what Ive read, your supposed to put Super One + on a thin area of skin, such as the top of your feet. I hear it can get a bit stingy, and you want to wash your hands throughly when your done, because if it gets in your eyes, or any cuts or your balls for that matter, it can sting.

Hope that helps.

Originally posted by Prince
yeah, it was a simple fricking question.

No. It is systemic.