Thread: non-steroidal anti-inflammatory and with steriod.. what's different ??

steroidal anti-inflamm. are stronger of course...it has to do with how they block prostaglandin synthesis which is responsible for the inflammatory and pain response.

although they are stronger, they also have a much higher incidence of side effects so i would stick to the NSAIDS or a more natural alternative unless it is absolutely neccessary to use the steroidal anti-inflammatoy meds.

Don't forget that cortisone / prednosone etc (corticosteroids) are all fairly catabolic, wasting protein and storing fat. I would think that localized cortisone injections would be more efficient than the more systemic prednosone / orals. Even the local injects will travel through the body, but it seems you could get away with a lower well placed dose. Just MHO, I'm no doc, but i've read up on and had to use anti inflamatories in the past. Many times 800-1200 mg of motrin (NSAID) works pretty well for simple tendonitis.