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Better than Tamoxifen



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Old 12-09-2004, 11:36 AM   #1
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Better than Tamoxifen

This talks about Arimixdex being better than Tamoxifen. One paragraph that really gets my attention is:

"Arimidex, known generically as anastrozole, is one of three newer drugs called aromatase inhibitors, which prevent estrogen from being made in the first place instead of just keeping it from entering cells."

http://www.freep.com/news/nw/cancer9e_20041209.htm

Thoughts on what this could mean for the bodybuilding community?



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Old 12-09-2004, 11:43 AM   #2
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Prolly nothing, some estrogen is good.

A good example is DHT and hairloss. You have DHT inhibitors and DHT Blockers. Inhibitors will prevent DHT from being made which is good for your hair, but it is bad in that other things use DHT, such as your wang. Now, a blocker, such as nolvadex with estrogen, would block the binding at the site, allowing the hormone to exert it's effects elsewhere. This is why people take spiro over propecia, it is not systemic so it will have fewer sides.

Nolvadex is different in that it is tissue specific and not topical, but you get the idea.



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Old 12-09-2004, 12:03 PM   #3
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someone recommended this for me on my test/dbol cycle, i haven't done any research on it yet so i wouldn't want to recommend it myself, be interesting to see what the others say
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Old 12-09-2004, 12:48 PM   #4
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It's not new. Not good for post cycle. It's basically used on cycle to combat estrogen.



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Old 12-09-2004, 03:31 PM   #5
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Different compounds...different actions...different uses.



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Old 12-09-2004, 03:38 PM   #6
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Quote:
Originally Posted by young d
someone recommended this for me on my test/dbol cycle, i haven't done any research on it yet so i wouldn't want to recommend it myself, be interesting to see what the others say
You could also use Femara, which is a very effective AI.
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Old 12-09-2004, 04:41 PM   #7
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apparently you can't use arimidex and nolva together, but i've heard you can use something called letrozole and nolva, got a friend who recommends letro on cycle then adding in nolva if gyno symptoms start occuring, anyone else used letrozole and recommend it?
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Old 12-09-2004, 04:51 PM   #8
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Letrozole and femara are the same thing. I've used it to reduce bloat and it's very effective. Use a low dose though, otherwise it can dry out your joints and reduce libido.
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Old 12-09-2004, 05:53 PM   #9
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Quote:
Originally Posted by redspy
Letrozole and femara are the same thing. I've used it to reduce bloat and it's very effective. Use a low dose though, otherwise it can dry out your joints and reduce libido.


how much is a low dose? you take it on cycle i assume for how long? do you just use it for gear or with certain PH's too? where can I find it, chemist or is it illegal?
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Old 12-09-2004, 05:58 PM   #10
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im going to run 1/2 mg EOD with a test/dbol cycle
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Old 12-09-2004, 06:07 PM   #11
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Quote:
Originally Posted by dg806
It's not new. Not good for post cycle. It's basically used on cycle to combat estrogen.
yup, what he said^

it's an aromatase inhibitor as opposed to an anti-estrogen.

godjs is using the correct mg of rimi for a cycle of test dbol.



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Old 12-09-2004, 06:55 PM   #12
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I'm going to do .25 mg ed of femera (letro) and 20 mg nolva with test/d-bol. 10 mg/nolva with 12.5mg d-bol twice daily. I'll probably drop the nolva down to 10 mg/day after the d-bol phase. I'll let you know how its working in about a week. I'm using tamoxifen pills--makes twice daily dosage not so bad.
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Old 12-09-2004, 08:02 PM   #13
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Quote:
Originally Posted by PirateFromHell
I'm going to do .25 mg ed of femera (letro) and 20 mg nolva with test/d-bol. 10 mg/nolva with 12.5mg d-bol twice daily. I'll probably drop the nolva down to 10 mg/day after the d-bol phase. I'll let you know how its working in about a week. I'm using tamoxifen pills--makes twice daily dosage not so bad.
I assume your running a 10-12 week cycle, are you planning on running the nolva throughout? Why not run the nolva until the femera has time to get into your system? Just wondering because dbol is already hard on the liver and nolva can possibly be as well. Also are you going to run any HCG?
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Old 12-09-2004, 08:58 PM   #14
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Quote:
Originally Posted by PirateFromHell
I'm going to do .25 mg ed of femera (letro) and 20 mg nolva with test/d-bol. 10 mg/nolva with 12.5mg d-bol twice daily. I'll probably drop the nolva down to 10 mg/day after the d-bol phase. I'll let you know how its working in about a week. I'm using tamoxifen pills--makes twice daily dosage not so bad.
do you really need both the letro and the nolva on cycle? i was just gonna run the letro then get on the nolva if i see any gyno, wouldn't the nolva just be a waste of money if your estrogen is under control? (and the point golcocs mentioned about the liver being put under extra stress)

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Old 12-09-2004, 09:11 PM   #15
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Quote:
Originally Posted by gococksDJS
I assume your running a 10-12 week cycle, are you planning on running the nolva throughout? Why not run the nolva until the femera has time to get into your system? Just wondering because dbol is already hard on the liver and nolva can possibly be as well. Also are you going to run any HCG?
12 weeks, nolva throughout, femera doesn't take much time to get into your system as far as I understand it, not worried about nolva stessing the liver. HCG is a must.
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Old 12-09-2004, 09:54 PM   #16
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I believe that taking AIs and SERMs simultaneously will reduce the effectiveness of the AI by around 20%. Personally I'd only take Nolva on cycle to control gyno issues. Each to their own
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Old 12-09-2004, 09:56 PM   #17
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I can always adjust if necessary. I just want to take some nolva with the d-bol.
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Old 12-09-2004, 09:57 PM   #18
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Quote:
Originally Posted by young d


how much is a low dose? you take it on cycle i assume for how long? do you just use it for gear or with certain PH's too? where can I find it, chemist or is it illegal?
Pirate's suggestion of 25 mg ed sounds good to me. You can buy AIs as research chems. Failing that you could buy from an online pharmacy. If you need more info PM me.
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Old 12-09-2004, 10:16 PM   #19
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I'll look for AI's later... looking for pill form Tamoxifen now... my mice can't stand the taste of this research chemical!



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Old 12-10-2004, 07:40 PM   #20
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what about Proviron? that any good?

my main worry is gonna be gyno, just read about a buddy of mine who got it and i really don't want that shit happening to me, he was running nolva and something else during cycle and it still got him before the end of 8 weeks! might cut my 1st cycle down to an 8 weeker

i've decided on nolva pct, just not sure what to prevent gyno + bloat whilst on... letro+nolva or proviron+nolva by the looks of things

sound alright?
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Old 12-10-2004, 07:49 PM   #21
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Quote:
Originally Posted by young d
what about Proviron? that any good?

my main worry is gonna be gyno, just read about a buddy of mine who got it and i really don't want that shit happening to me, he was running nolva and something else during cycle and it still got him before the end of 8 weeks! might cut my 1st cycle down to an 8 weeker

i've decided on nolva pct, just not sure what to prevent gyno + bloat whilst on... letro+nolva or proviron+nolva by the looks of things

sound alright?
I'd recommend letro while on cycle to reduce bloat, but have Nolva ready in case you get gyno symptoms. For PCT use Nolva.
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