Liquid Glutamine any signifigance?

**andyo** · 12-21-2004, 03:33 AM

Hello all,

I have been trying out a new supplement from Sci-fit called 'Glutamine Fusion', which is a liquid glutamine supp.

Question: Although I don't notice any change, will it cause water retention at all, or make a 'heavy' feeling?

Any input would help
Andy

**LAM** · 12-21-2004, 10:10 AM

I don't think that L-Glutamine remains stable in suspension...

**Robboe** · 12-21-2004, 12:52 PM

What does it break down into?

**redspy** · 12-21-2004, 02:54 PM

In liquid solutions, L-glutamine is unstable at 4°C or higher temperatures. The molecule dissociates and toxic ammonium is created as a waste product of that reaction. This limits the stability of cell culture media; as a consequence, stock solutions of L-glutamine or solutions containing L-glutamine should be stored frozen. In addition, cell culture media should be changed frequently to ensure availability of this amino acid.

Dipeptides containing L-glutamine are extremely well suited to replace L-glutamine. They are stable over long periods of time, even when stored at room temperature. Cells can retrieve L-glutamine by cleaving the peptide bond. PromoCell offers several media with stable L-glutamine in the form of N-acetyl-L-Ala-L-Glu. The amount of available L-glutamine corresponds to that of L-glutamine normally present in the equivalent medium after the addition of the appropriate amount of L-glutamine.

Source: http://www.promocell.com/en/Page0502_TE_02_LC.htm