Curlingcadys

I don't think there would be a problem but I want to be sure being I have a lil keg gathering this weekend; is there any issues know with drinking and being on a s1+ cycle? I know you're not sapposed to with m1t but obviously there is quite the difference between m1t and s1+.

Cold Iron

you shouldnt drink on any ph's or AAS

Tha Don

obviously you shouldn't drink when on steroids as the alcohol is gonna totally wipeout the benefit of the increased nitrogen balance and higher protein synthesis n' all of that technical stuff

its even more risky when taking orals such as m1t and dbol as you'll be putting a lot of additional strain on an already overworked liver but obviously with topicals and injectables this won't be as much of an issue

my advice is do not drink full stop! but if you MUST (like going for a drink with a woman... so you really haven't got much choice unless you want to look like a vien unsociable prick! - which we all are anyway ) stick to 1 glass then go back to your pints of water

Cold Iron

haha young D.... hes talking about throwing a kegger. A little different than having 1 glass of wine

Tha Don

man alcohol should be avoided whether on cycle or off cycle, it totally shuts down growth, raises BP, increases risk of disease and other illnesses not to mention the liver and kidney problems it causes, i know its hard to cut down but if you were that serious you wouldn't drink at all, i never drink unless i'm on a date and it will be stricly 1 glass

peace

Tha Don

a kegger? wtf is that?

Curlingcadys

yeah I know but I'm not a lush like a few years ago, I maybe throw a few back on occasion maybe 4-5 times a year tops. I just wasn't sure if the mix from s1+ and alcohol would be hard on me, such as if I were to take m1t and drink. But if its really gonna work against the cycle then screw it, I'll be sober and laugh at the drunks!

and wish I could be one of them...

Curlingcadys

one great saturday! lotso beer!

topolo

dont drink the s1....it will burn your throat

Curlingcadys

glad you told me I was just making a mixer with it! whew!

bigss75

Is a keg 18 gallons?

Tha Don

Curlingcadys

thats a mighty fine question, not sure...

Curlingcadys

so is there any other opinions on this, not that I don't hold yours valuable young d I just like to hear/read from a couple people.

Question being: Will I totally screw up my s1+ cycle or hurt myself medically with 1 night of drinking? FYI: I just started the cycle Monday.

Now yes I know in general drinking isn't wise but in my opinion a night here and there isn't going to destroy you persay. But however I don't want to severely screw my cycle.

PreMier

Each drink, will decrease protein synthesis by 20%. So after 5, you will totally fuck up your cycle for the next few days.. I wouldnt do it, unless you thought that S1+ was cheap.

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"the post-workout high is more profound than any drug-induced rush imaginable." -Dante B.

Curlingcadys

no no, blue collar worker here every penny counts!
It is my lil bro's bachelor party but if its going to set my progress back that dramaticly then he'll just have to understand...Thanks for the feedback everyone.

stikyicky

fuck a keger wow.. i threw a freakin 5 keger it was bomb! haha..skeet skeet! haha..but curli is to young to drink he is gonna die!

thatguy

Brits...

Curlingcadys

you remind me of that fly that keeps landing on your face when you're trying to take a nap in the summer time, you just wont go away will ya. Your like a fucking bad case of herpes, you know, like your mom had. Don't you have some flash cards to go practice or something? And I highly doubt you through a 5 keger you're barley old enough to drive

Stu

In british terms, its a few warm-up drinks before you go out

Curlingcadys

Pirate!

I don't know about percentages, but obviously alcohol will lessen your potential gains. I've hung out with my friends while they are drinking and it isn't really much fun for me or them. There is little harm in one drink. If it is a kegger, then you are likely drinking some domestic lager. If you are going to drink, have one every other hour with water in between. You won't get drunk or saturate your system enough to cause problems or setbacks, and you will get to participate with the boys. BTW, we used to get kegs of Bass, Guinness, Heineken, Sierra Nevada Pale Ale, Anchor Steam Liberty Ale etc.... Now, I know better.

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Robboe

Where did you get that figure from?

Being held down by The Man

sawastea

I'm pretty sure a full size keg is 180 cups...

I'm Trying

I wouldn't drink at all.

The beatings will continue until morale improves!!

Personal Goal: I WILL be playing "C" tournament ball next year!!!

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Du

That sounds like a voice of experience.

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sawastea

4 years at the Univ of Florida will do it to you

MANY nights of late night drinking and binge eating. I paid the price (weight) but have learned my lesson

Curlingcadys

wow we have totally different taste buds!! Were having miller light and bud light

PreMier

From my ass.. oh, and it has a brain.


Alcohol impairs protein synthesis and degradation in cultured skeletal muscle cells.

Hong-Brown LQ, Frost RA, Lang CH.

Department of Cellular and Molecular Physiology, Pennsylvania State College of Medicine, Hershey, Pennsylvania 17033, USA. lqh10@psu.edu

BACKGROUND: Acute and chronic alcohol intoxication decreases skeletal muscle protein synthesis under in vivo conditions. We investigated whether ethanol (EtOH) and its major metabolites, acetaldehyde and acetate, can directly modulate protein balance under in vitro conditions. METHODS: Human myocytes were incubated with different doses of EtOH for varying periods of time (i.e., 4-72 hr). Alternatively, cells were incubated with acetaldehyde, acetate, insulin, insulin-like growth factor-I (IGF-I), or with a combination of EtOH plus insulin or IGF-I. Rates of protein synthesis or degradation were determined by 35S-methionine/cysteine incorporation into or release from cellular protein. RESULTS: A significant, 15% to 20%, decrease in basal protein synthesis was observed after 24 hr, but not at earlier time points, in response to 80 mM EtOH. Incubation of myocytes for 72 hr decreased synthesis in cells incubated with EtOH ranging between 60 and 120 mM. The ability of IGF-I or insulin to stimulate protein synthesis was impaired by 30% and 60%, respectively, in cells incubated with 80 mM EtOH for 72 hr. Exposure of cells to 200 microM acetaldehyde or 5 mM Na-acetate also decreased basal protein synthesis. In contrast, neither EtOH, acetaldehyde, nor acetate altered the basal rate of protein degradation. However, EtOH completely impaired the ability of insulin and IGF-I to inhibit proteolysis. Finally, EtOH did not impair IGF-I receptor autophosphorylation, but inhibited the ability of insulin to phosphorylate its own receptor. EtOH also did not alter the number of insulin or IGF-I receptors or the formation of insulin/IGF-I hybrid receptors. CONCLUSIONS: We have demonstrated that EtOH can directly inhibit muscle protein synthesis under in vitro conditions. Neither EtOH nor its metabolites altered basal protein degradation, although EtOH did compromise the ability of both insulin and IGF-I to slow proteolysis. This impairment seems to be mediated by different defects in signal transduction.

PMID: 11584159 [PubMed - indexed for MEDLINE]

P-side Inc.

"the post-workout high is more profound than any drug-induced rush imaginable." -Dante B.

LAM

1/2 keg = 7 cases of beer

Dumbest statement made in the Anabolic Zone for Nov

TBD

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What you talking about Willis ?