Looks pretty solid, though i dont know much of the merits of this orotic acid, nor the NAC
Anyone try it? http://www.bulknutrition.com/?products_id=1784
Search feature brought up only one previous thread and it had zero responses. I have heard funny things about the "tingling" sensation this supplement supposedly has. I have also heard that it's got a weird taste. Would anyone care to comment? I plan to start using this supplement soon.
Supplement Facts
Serving Size: 1 scoop (10.5g)
Servings per Container: 50
Amount Per Serving
OROTINE™ (Tricreatine Orotate)
3,000mg +
N-Acetyl-Cysteine
2,000mg +
Beta-Alanine
1,600 mg +
MAG-MALATE™ (Magnesium Malate)
560.5mg +
Orotic Acid
500mg +
Vinpocetine
8mg +
PHOSPHA-DRIVE™
Magnesium Phosphate, Dibasic
351.5mg +
Potassium Phosphate, Dibasic
220mg +
Sodium Phosphate, Monobasic
216mg +
+ Daily Value not established
Other Ingredients: Natural and Artificial flavors, Maltodextrin, Citric acid, sucralose, Red#40, Acesulfame Potassium.
"Recommended Use: To optimize uptake and absorption of CLOUT™ take one serving twice daily, one immediately preworkout and one with food separated by at least a 4-5 hour period. Following this routine for 28 days will optimize concentrations of the ingredients in CLOUT™ in muscle tissues. Noticeable effects should be experienced within the first 3 days of use with 80% of total effectiveness achievable by day 12-14 and total effects at 28 days and longer. CLOUT™ can be combined with BODYOCTANE™ and SCORCH™."
Looks pretty solid, though i dont know much of the merits of this orotic acid, nor the NAC
This is my journal. Click it and such
"tried and true theory on one's self is probably the only non-biased proof that something works for someone." - juggernaut
http://www.ronpaul.com/
Thanks for the reply Fish, it makes me feel more comfortable with my decision to order Clout. Have you tried any other supplements comparable to Clout in terms of ingredients? How were they for you?
I don't know much about orotic acid or N-Acetyl-Cysteine. Bulk Nutrition has this description (likely from MAN Sports):
CLOUT™ also provides the exact level of Orotic Acid shown to work effectively on two levels:
1. Enhancement of performance. This may have been achieved by a selection of mechanisms but of most importance is as a precursor for carnosine synthesis. In fact research proves that Orotic Acid is very much a nutrient that can increase muscle carnosine levels11.
2. Orotic Acid has been shown to increase muscle Uridine levels. Work by Rosenfeldt et al. (1998) showed under hypoxic (lack of oxygen) conditions (found following anaerobic exercise) elevation of intramuscular Uridine levels increased muscle phosphocreatine and creatine levels 38% and 3%, respectively12.
Elevated Uridine levels, a RNA base, has been shown to increase muscle contractile capacity.
That not all…Orotic Acid has been proven to:
1. Enhance and Maintain ATP pools
2. Increase Glucose Uptake
3. Increase Ribose Moieties (R-1-P & R-5-P) Leading to Enhanced Ribose Formation
4. Increased Muscle Carnosine Stores
5. Support and Enhance Muscle Hypertrophy (via RNA synthesis support during growth)
AND
BIOACTIVE #4 N-Acetyl Cysteine (NAC)
WHAT IS IT?
Acetyl group donation as mentioned earlier a donor of acetyl groups could radically impact performance by activating the PDH complex. One such acetyl donating nutrient is the antioxidant N-Acetyl cysteine. However, the great effects of NAC don't stop at delivering acetyl groups.
HOW DOES IT WORK?
N-Acetyl cysteine again is a powerful antioxidant and its main influence on muscle damaging free radicals is its influence at enhancing muscle and other cell glutathione levels[15]. Secondly, it can also provide acetyl groups which could be used for entry into the Krebs cycle and energy generation overcoming deficiencies in the PDH complex.
WHAT EVIDENCE FOR PERFORMANCE EFFECT?
There are two immense supplementation studies that show the influence of cysteine donors on performance. Sen et al. (1994) gave 200 x 4mg/day of NAC and an 800mg bolus before a maximal bike test16. CLOUT™ delivers probably the highest amounts of NAC in any sports supplement many times above the cysteine and acetyl groups delivered in these studies! OK back to the outcome of the Sen study, NAC resulted in a higher net post exercise antioxidant capacity16. But can elevating oxidative capacity through cysteine donation influence performance? The answer is simply YES! A study presented at the ACSM on whey protein delivering similar cysteine levels to those in CLOUT™ improved muscle fatigue during fatiguing leg extension exercise17.
DISCLAIMER: