12.22 Goofy "Muscle-building" Supplements Busted

oaktownboy · 12-23-2006, 03:50 AM

http://www.musculardevelopment.com/content/view/329/51/

"A recent study at the Baylor University's Exercise & Sport Nutrition Laboratory (ESNL) investigated whether some supposed "muscle-building" supplements, namely methoxyisoflavone, 20-hydroxyecdysone and sulfo-polysaccharide, affect training adaptations and/or markers of muscle anabolism/catabolism. Forty-five male gym rats were matched according to fat-free body mass and randomly assigned to ingest in a double-blind manner either an inactive fake supplement, 800 milligrams per day of methoxyisoflavone, 200 milligrams per day of 20-hydroxyecdysone or 1,000 milligrams per day of sulfo-polysaccharide for eight weeks during training....the results strongly suggest that these "muscle-building" supplements are absolutely useless. In other words, the investigators reported that these products didn't affect anabolic/catabolic markers (e.g., cortisol), body composition or training adaptations. Thus, I feel you shouldn't spend any money on such products. Stick with proven sports supplements, such as creatine monohydrate, leucine and beta-alanine. "

i don't think anyone believed methoxyisoflavone was actually effective in building muscle; not at the rate it costs the consumer for one bottle anyways.

Bernie2 · 12-23-2006, 10:39 AM

I learned that methoxy was worthless from experience. It is amazing how much false information is out there saying it is great.

**Mudge** · 12-23-2006, 07:15 PM

What is even more amazing are their profit margins!

Good lookin out Oak!

depaul · 12-23-2006, 10:26 PM

Very interesting...just shows why studies on most supplements (creatine and a few others excluded, since they are actually backed up by studies) don't ever get done - they'll just provide evidence that the supplements are basically ineffectual.

Wonder who sponsored the study you are citing; certainly not any of the supplement companies :P

AKIRA · 12-23-2006, 11:30 PM

What products contain these? Maximum Pump?

**Prince** · 12-24-2006, 09:07 PM

Quote:

Originally Posted by oaktownboy

"A recent study at the Baylor University's Exercise & Sport Nutrition Laboratory (ESNL) investigated whether some supposed "muscle-building" supplements, namely methoxyisoflavone, 20-hydroxyecdysone and sulfo-polysaccharide, affect training adaptations and/or markers of muscle anabolism/catabolism.

I did not know that Methoxyisoflavone was being sold as a "muscle builder"?
I thought is was for preventing osteoporosis, reducing cholesterol and other "health benefits'.

depaul · 12-25-2006, 11:56 AM

Quote:

Originally Posted by Prince

I did not know that Methoxyisoflavone was being sold as a "muscle builder"?
I thought is was for preventing osteoporosis, reducing cholesterol and other "health benefits'.

You are absolutely correct though, it was used for osteoporosis first. It was latched onto by the bodybuilding community, not sure why. Do a quick google search on "methoxyisoflavone" and a bunch of bodybuilding sites come up. From supplementwatch.com:

"Ipriflavone is more commonly thought of as a "bone health" supplement due to the ability of this synthetic isoflavone to slow bone loss in postmenopausal women. Among body-builders, however, ipriflavone is now thought of as a way to build muscle and lose body fat - though credible research evidence for this effect is lacking. "

http://supplementwatch.com/reviews/d...templateId=101
if you want to read the whole article.

Twin Peak · 12-26-2006, 02:06 PM

Quote:

Originally Posted by Keven95

Food is the best "supplement."

This is such a stupid post. I would have berated you, but I like your avatar.

bludevil · 12-26-2006, 02:26 PM

Quote:

Originally Posted by Twin Peak

This is such a stupid post. I would have berated you, but I like your avatar.

12-23-2006, 03:50 AM	#1
oaktownboy Registered User Join Date: Jun 2003 Location: smog and fog Posts: 4,392	12.22 Goofy "Muscle-building" Supplements Busted http://www.musculardevelopment.com/content/view/329/51/ "A recent study at the Baylor University's Exercise & Sport Nutrition Laboratory (ESNL) investigated whether some supposed "muscle-building" supplements, namely methoxyisoflavone, 20-hydroxyecdysone and sulfo-polysaccharide, affect training adaptations and/or markers of muscle anabolism/catabolism. Forty-five male gym rats were matched according to fat-free body mass and randomly assigned to ingest in a double-blind manner either an inactive fake supplement, 800 milligrams per day of methoxyisoflavone, 200 milligrams per day of 20-hydroxyecdysone or 1,000 milligrams per day of sulfo-polysaccharide for eight weeks during training....the results strongly suggest that these "muscle-building" supplements are absolutely useless. In other words, the investigators reported that these products didn't affect anabolic/catabolic markers (e.g., cortisol), body composition or training adaptations. Thus, I feel you shouldn't spend any money on such products. Stick with proven sports supplements, such as creatine monohydrate, leucine and beta-alanine. " i don't think anyone believed methoxyisoflavone was actually effective in building muscle; not at the rate it costs the consumer for one bottle anyways.

12-23-2006, 10:39 AM	#2
Bernie2 Registered User Join Date: Dec 2006 Posts: 48	Thanks for the info! I learned that methoxy was worthless from experience. It is amazing how much false information is out there saying it is great.
Bernie2 Registered User Join Date: Dec 2006 Posts: 48

12-23-2006, 07:15 PM	#3
Mudge Pizza the Hut Super Moderator Join Date: Jun 2002 Posts: 23,074 Photos: 1	What is even more amazing are their profit margins! Good lookin out Oak!
	Kinesiology Vote @ Top 25 Deads Comp Bench Motivation Bench form MaxCalc Charles Poliquin When I let go of what I am, I become what I might be. Lao-Tzu I don't know any sources so don't ask - thanks

12-23-2006, 11:30 PM	#5
AKIRA I am Rollo Tomassee.. Elite Member Join Date: Jul 2005 Location: Outside the box Posts: 7,918 Photos: 3	What products contain these? Maximum Pump?
	6' 209lbs (8/16) Bench 360 (11/29) Weighted Pullups 80lbs 3x3 (3/19) Squat 370 Deadlift after herniation 385lbs 3x3 (3/17) NASM certified 2/06 Journal

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12-23-2006, 10:26 PM	#4
depaul Registered User Join Date: Dec 2006 Location: Wichita, KS Posts: 56	Very interesting...just shows why studies on most supplements (creatine and a few others excluded, since they are actually backed up by studies) don't ever get done - they'll just provide evidence that the supplements are basically ineffectual. Wonder who sponsored the study you are citing; certainly not any of the supplement companies :P